Filetype
Purpose: To study the effectiveness of Exergames in communal psychiatry for persons with severe mental illness, a randomized cluster study was performed. The hypothesis was to increase physical activity habits to improve somatic health. To identify factors promoting or impeding the use of the Exergames. Methods: Assessments of BMI, blood pressure, physical fitness, SF36, GAF and social interaction
A new health surveillance protocol for work-related upper-extremity musculoskeletal disorders has been validated by comparing the results with a reference protocol. The studied protocol, Health Surveillance in Adverse Ergonomics Conditions (HECO), is a new version of the reference protocol modified for application in the Occupational Health Service (OHS). The HECO protocol contains both a screenin
Volatile organic compounds (VOCs) in biological samples have gained popularity for disease monitoring and diagnosis. Celiac disease (CD) is one of the many prevalent health conditions which are challenging to diagnose. The aim of this study was to optimize a solid phase microextraction followed by gas chromatography-mass spectrometry, for quantitative analysis of a wide range of VOCs in the urine
Partially premixed combustion aims to reduce NOx and particulate matter emission without fuel consumption penalty. Low temperature heat release (LTHR) is an important process to be investigated. A novel motoring pressure prediction algorithm based on variable polytropic exponents was introduced and utilized to estimate average heat transfer coefficient as well as heat dissipation for real-time app
Fragmin and heparin were studied in pigs during 120 min of cardiopulmonary bypass (CPB) and up to 240 min postoperatively, with respect to clotting, bleeding and the effects of protamine. Thirty-three pigs received bolus injections of 300 IU/kg with or without additional dosage during CPB and with or without subsequent protamine sulphate. Doses of Fragmin 60% higher were necessary to prevent clott
OBJECTIVE: To analyze the association between rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis and hospitalization for psychiatric disorders, as well as the association between hospitalization for dementia or delirium and systemic lupus erythematosus, by using a novel, large-scale approach.DESIGN: Cohort study with follow-up between 1973 and 2004.PARTICIPANTS: The ent
BACKGROUND: The aim of this study was to investigate the possibility of using extended-wavelength diffuse reflectance spectroscopy (EW-DRS) to measure tissue response related to blood perfusion. The study was performed on a model that we have previously found to be useful for studying techniques for perfusion monitoring following the injection of epinephrine in a local anesthetic in the human fore
Industrial Symbiosis (IS) is a collective approach to competitive advantage in which separate industries create a cooperative network to exchange materials, energy, water and/or by-products. By addressing issues related to resource depletion, waste management and pollution, IS plays an important role in the transition towards sustainable development. In the literature, two conceptual perspectives
Magnetoliposomes (MLs) were synthesized and tested for longitudinal monitoring of transplanted pancreatic islets using magnetic resonance imaging (MRI) in rat models. The rat insulinoma cell line INS-1E and isolated pancreatic islets from outbred and inbred rats were used to optimize labeling conditions in vitro. Strong MRI contrast was generated by islets exposed to 50 µg Fe/ml for 24 hours witho
This work investigates the stability of emulsions prepared by using octenyl succinic anhydride (OSA)-modified waxy maize starch in the form of granules, dissolved starch, and non-solvent precipitated starch as Pickering emulsion stabilisers. The aim of this study was to investigate the effects of different forms of starches on the stability of emulsion using light microscopy, light scattering, and
Background: There exist few recovery and occupation-based interventions for mental health service users. Balancing Everyday Life (BEL) is a new occupation-based lifestyle intervention that was created to fill this need. Aim: To gain group leaders’ and participants’ perspectives of the BEL intervention content and format, including factors that helped, hindered, and could be improved. Methods: A co
Background: Metronidazole is the preferred empirical anti-anaerobic agent for patients with suspected anaerobic infection. The balance between benefits and harms of empirical metronidazole is unclear. We aimed to assess patient-important benefits and harms of empirical metronidazole vs placebo/no treatment in adult patients with severe bacterial infection of any origin. Methods: We conducted a sys
The sharing economy is a new form of resource distribution that is affecting traditional markets, cities and individuals, and challenging the prevalent regulatory frameworks, social norms and belief systems. While studies have examined some of its disruptive effects on institutional actors, there has been less focus on the ways in which sharing economy organisations work to create new or disrupt p
Accurate histological classification and identification of fusion genes represent two cornerstones of clinical diagnostics in non-small cell lung cancer (NSCLC). Here, we present a NanoString gene expression platform and a novel platform-independent, single sample predictor (SSP) of NSCLC histology for combined, simultaneous, histological classification and fusion gene detection in minimal formali
Migraine is a common, severe disease, affecting the brain and blood vessels, causing much pain, time missed from work and family, and severe disability. It affects approximately 12% of most Western populations studied and affects women three times more than men. Cluster headache is a much less common dysfunction of the hypothalamus, involving the sphenopalatine ganglion and other areas; it causes
Purpose: The small molecule inhibitors larotrectinib and entrectinib have recently been approved as cancer agnostic drugs in patients with tumours harbouring a rearrangement of the neurotrophic tropomyosin receptor kinase (NTRK). These oncogenic fusions are estimated to occur in 0.1–3 % of non-small cell lung cancers (NSCLC). Although molecular techniques are most reliable for fusion detection, im
Loss of forest naturalness challenges the maintenance of green infrastructure (GI) for biodiversity conservation and delivery of diverse ecosystem services. Using the Convention on Biological Diversity's Aichi target #11 with its quantitative and qualitative criteria as a normative model, we aim at supporting landscape planning through a pioneering assessment of the extent to which existing amount
The comparative study of planetary systems is a unique source of new scientific insight: following the six “key science questions” of the “Planetary Exploration, Horizon 2061” long-term foresight exercise, it can reveal to us the diversity of their objects (Question 1) and of their architectures (Question 2), help us better understand their origins (Question 3) and how they work (Question 4), find
