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A kinetic model for quantitative evaluation of the effect of hydrogen and osmolarity on hydrogen production by Caldicellulosiruptor saccharolyticus

Background: Caldicellulosiruptor saccharolyticus has attracted increased interest as an industrial hydrogen (H2)producer. The aim of the present study was to develop a kinetic growth model for this extreme thermophile. The model is based on Monod kinetics supplemented with the inhibitory effects of H2 and osmotic pressure, as well as the liquid-to-gas mass transfer of H2. Results: Mathematical exp

The emergence and spread of tick-borne encephalitis virus in scandinavia

Tick-borne encephalitis virus (TBEV) is a high-impact pathogen with approximately 12,000 diagnoses annually in Eurasia. The virus causes a variety of clinical manifestations, with neurological symptoms in up to 30% of the patients. Lethality in Europe is <2% but post-encephalitis syndrome is seen in over 40% of the infected patients and results in substantial impairment in quality of life. Over th

A non-linear model of hydrogen production by Caldicellulosiruptor saccharolyticus for diauxic-like consumption of lignocellulosic sugar mixtures

Background: Caldicellulosiruptor saccharolyticus is an attractive hydrogen producer suitable for growth on various lignocellulosic substrates. The aim of this study was to quantify uptake of pentose and hexose monosaccharides in anindustrial substrate and to present a kinetic growth model of C. saccharolyticus that includes sugar uptake on defined and industrial media. The model is based on Monod

Solvability of subprincipal type operators

In this paper we consider the solvability of pseudodifferential operators in the case when the principal symbol vanishes of order k ≥ 2 at a nonradial involutive manifold Σ2. We shall assume that the operator is of subprincipal type, which means that the kth inhomogeneous blowup at Σ2 of the refined principal symbol is of principal type with Hamilton vector field parallel to the base Σ2, but trans