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Initiation of protein synthesis and heat-shock protein-72 expression in the rat brain following severe insulin-induced hypoglycemia

Following stress such as heat shock or transient cerebral ischemia, global brain protein synthesis initiation is depressed through modulation of eucaryotic initiation factor (eIF) activities, and modification of ribosomal subunits. Concomitantly, expression of a certain class of mRNA, heat-shock protein (HSP) mRNA, is induced. Here we report that the activity of eucaryotic initiation factor-2 (eIF

Changes in insulin-like growth factor 1 receptor density after transient cerebral ischemia in the rat : Lack of protection against ischemic brain damage following injection of insulin-like growth factor 1

Binding of 125I-insulin-like growth factor-1 (125I-IGF-1) to rat brain slices was studied after 15 min of two-vessel occlusion ischemia and 1 h to 4 days of recirculation. Ligand binding in the hippocampus increased at 6 h post ischemia in the CA1 and CA3 regions and the dentate gyrus, suggesting that the IGF-1 receptors were up-regulated, while no change was seen in neocortex and striatum. Intrac

Effects of ischemia on regional ligand binding to adrenoceptors in the rat brain

Changes in ligand binding to adrenoceptors ([3H]prazosin to α1-receptors, [3H]idazoxan to α2-receptors and [125I]cyanopindolol to β-receptors) following transient cerebral ischemia were investigated using autoradiographic methods. The binding was quantified in brain sections from control rats, rats subjected to 15 min of 2-vessel occlusion ischemia, and rats with recirculation times of 1 h, 1 week

Activation of p53 and its target genes p21(WAF1/Cip1) and PAG608/Wig-1 in ischemic preconditioning

A brief, 3 min period of global forebrain ischemia in the rat, induced by bilateral common carotid occlusion combined with hypotension, confers resistance to hippocampal pyramidal neurons against a subsequent 10 min ischemia, which is normally lethal to these cells. The molecular mechanisms underlying this ischemic preconditioning, or tolerance, are poorly understood. The tumor suppressor p53 is a

The distribution of hypoglycemic brain damage

Rats were exposed to insulin-induced hypoglycemia resulting in periods of cerebral isoelectricity ranging from 10 to 60 min. After recovery with glucose, they were allowed to wake up and survive for 1 week. Control rats were recovered at the stage of EEG slowing. After sub-serial sectioning, the number and distribution of dying neurons was assessed in each brain region. Acid fuchsin was found to s

Vt13-kp-ksmc22-2012-12-18

1. Fastställande Kursplanen är granskad av Styrelsen för institutionen för service management 2012-11-13 och senast reviderad 2012-12-18. Den reviderade kursplanen gäller från och med 2013-01-01. Utbildningsområde: Samhällsvetenskapligt 100% Ansvarig institution: Inst för Service Management 2. Allmänna uppgifter Kursen ingår inte i ett huvudområde. Kursen ingår i kandidatprogrammet för Service Man

https://www.ses.lu.se/sites/ses.lu.se/files/vt13-kp-ksmc22-2012-12-18.pdf - 2026-05-28

Asp-sociologi-20250424

Allmän studieplan för utbildning på forskarnivå i sociologi Sida 1 av 9 Fakultetsstyrelsen ALLMÄN STUDIEPLAN SOCIOLOGI Diarienummer U 2025/221 Datum 2025-04-24 Allmän studieplan för utbildning på forskarnivå i sociologi Allmän studieplan för utbildning på forskarnivå i sociologi är fastställd av Samhällsvetenskapliga fakultetsstyrelsen 2025-04-24, dnr U 2025/221. Studier enligt denna allmänna stud

https://www.soc.lu.se/sites/soc.lu.se/files/2025-05/asp-sociologi-20250424.pdf - 2026-05-28

Tracking environmental changes of the Baltic Sea coastal zone since mid-Holocene

Popular Abstract in Swedish I min avhandling har jag studerat marina sedimentkärnor från två kustområden i SE Sverige, dels från Gåsfjärden, strax söder om Västervik i Småland, och dels från kusten utanför Karlskrona i Blekinge. Med syftet att studera hur Östersjöns kustmiljö har förändrats sedan mitten av Holocen (~5000 år sedan). Resultaten visar att kustmiljön har påverkats av flera stressfaktoIn this thesis, I used two coastal sediment sequences from SE Sweden to study how Baltic Sea coastal environment has changed since the mid-Holocene. The results show the coastal environment has been influenced by multi-stressors, such as climate change, shoreline regression and anthropogenic activities. Using the sediment sequence from Karlskrona Bay, past coastal environment between 7300 and 350

Hemorrhage after ischemic stroke - relation to age and previous hemorrhage in a nationwide cohort of 58 868 patients

Background In randomized controlled trials of secondary prevention after stroke, the risk of hemorrhage varies between 1% and 5% per year in patients with antithrombotic therapy, i.e. anticoagulants and antiplatelets. Aim To explore the rate and the risk of hemorrhage after stroke in a nationwide cohort. Methods We identified 58 868 first ever ischemic stroke patients in the Swedish Stroke Registe

A bad start : The combined effects of early onset substance use and adhd and cd on criminality patterns, substance abuse and psychiatric comorbidity among young violent offenders

Substance abuse, conduct disorder (CD) and attention deficit/hyperactivity disorder (ADHD) are all known risk factors for developing aggressive behaviors, criminality, other psychiatric comorbidity and substance use disorders (SUD). Since early age of onset is important for aggravating the impact of several of these risk factors, the aim of the present study was to investigate whether young adult

The fate of fixed nitrogen in marine sediments with low organic loading : An in situ study

Over the last decades, the impact of human activities on the global nitrogen (N) cycle has drastically increased. Consequently, benthic N cycling has mainly been studied in anthropogenically impacted estuaries and coasts, while in oligotrophic systems its understanding is still scarce. Here we report on benthic solute fluxes and on rates of denitrification, anammox, and dissimilatory nitrate reduc

Internationalisering policy 2008 11

Lunds universitets internationella policy för 2008 – 2011 utgår från den strategiska planen 2007 – 2011 BESLUT Dnr RÄ 2007/357 Styrelsen 2007-12-17 Policy för internationalisering vid Lunds universitet 2008-2011 I denna policy1 för internationalisering formuleras gemensamma visioner, värderingar, mål och strategier för universitetets verksamheter.2 Internationaliseringsarbetets yttersta syfte är a

https://www.lu.se/sites/www.lu.se/files/internationalisering_policy_2008_11.pdf - 2026-05-28

Uppdrag-som-avdelningsforestandare-n-fak 190403

Postadress Box 117, 221 00 Lund Besöksadress Sölvegatan 27, Lund Telefon +46 46 222 48 54, 046-222 00 00 Mobil +46 72 704 70 70 E-post maria.ovesson@science.lu.se Webbadress www.naturvetenskap.lu.se Fakul te tss tyre lsen Uppdrag som avdelningsföreståndare Bakgrund Lunds universitets anger i Föreskrifter om ledningsuppdrag vid Lunds universitet (STYR 2018/1070), de chefs- och ledningsuppdrag som s

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/uppdrag-som-avdelningsforestandare-n-fak_190403.pdf - 2026-05-28

Projektplan-kvalitetsgranskning-s-fak-beslut

1 Kvalitetsgranskning och uppföljning av utbildning vid Samhällsvetenskapliga fakulteten Projektansvarig: Prodekan, Lena Eskilsson Projektledare: Lena Örnberg Projekttid: 2018-01-18 – 2019-01-17 Budget: Motsvarande 30% arbetstid, samt kostnader för studiebesök och ev piloter -------------------------------------------------- Underskrift av projektledare SYFTE Ta fram ett kvalitetssäkringssystem fö

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/projektplan-kvalitetsgranskning-s-fak-beslut.pdf - 2026-05-28

Strandfeldt evelina 2012020

LUCSUS Lund University Centre for Sustainability Studies “This will not be a problem in the future, when we all have electric cars” A sustainability perspective on planning practice of external commercial areas. A case study of three municipalities in Stockholm, Sweden. Evelina Strandfeldt Master Thesis Series in Environmental Studies and Sustainability Science, No 2012:020 A thesis submitted in p

https://www.lumes.lu.se/sites/lumes.lu.se/files/strandfeldt_evelina_2012020.pdf - 2026-05-28

Policy-brief-2019-final-draft barry ness

Solid Waste Management RECOMMENDATIONS FOR KISUMU, KENYA Mistra Urban Futures Policy Brief 2019:1 Kisumu City generates approximately 400 tonnes of solid waste per day, 20%- 25% of which is collected to the open dump site. Of the total municipal solid waste that is collected, 65% is organic and another 27% is recyclable (County of Kisumu, 2015). The collection and handling of municipal solid waste

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/policy-brief-2019-final-draft_barry_ness.pdf - 2026-05-28

Hsu hsin-chiang lukas

Negotiating the Climate Regime: The Process and Its Dynamics lukas LUMES Master’s Thesis 2004 Institutional Bargaining for the Climate Regime The Process and Its Dynamics Lukas Hsin-Chiang Hsu Graduate Institute of Diplomacy National Cheng-Chi University 116 Taipei, Taiwan E-mail:lukas866@hotmail.com Supervisor Karin Bäckstrand, PhD, Wallenberg Research Fellow Department of Political Science Lund

https://www.lumes.lu.se/sites/lumes.lu.se/files/hsu_hsin-chiang_lukas.pdf - 2026-05-28

Larsson maria

Master Thesis Lumes 1999/2000 LundUniversity Application of "Best Possible Technology" in Sweden with respect to Heating Systems in Buildings A study initiated by the Environmental Unit at Skanska Teknik AB By: Maria Larsson Richertsgatan 16 41260 Göteborg Sweden 031-126392 mala@hem.utfors.se Scientific Supervisor: Prof. em. Bo Adamson Lund Institute of Technology Department of Building Science Bo

https://www.lumes.lu.se/sites/lumes.lu.se/files/larsson_maria.pdf - 2026-05-28

Perez emili thesis 2011

Microsoft Word - EMILI PEREZ_LUMES_Thesis Sustainability Transition Nicaragua_SEP2011 Thesis submitted in partial fulfillment of the requirements of Lund University International Master’s Program in Environmental Studies and Sustainability Science Sustainability Transitions Exploring the Transformation of Nicaragua’s Electricity System from Fossil Fuels to Renewable Sources E E-MAIL Lund Universit

https://www.lumes.lu.se/sites/lumes.lu.se/files/perez_emili_thesis_2011.pdf - 2026-05-28