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Renin from plasma, kidney, and recombinant sources was previously demonstrated to cleave C3 to C3a and C3b. C3a was generated at a similar rate to that by C3 convertase, and C3 cleavage was inhibited by the renin inhibitor aliskiren. Renin endogenously produced by Calu6 cells also led to C3 deposition on cells. These results have been challenged by another group suggesting that recombinant renin d
Huvudhandledning. Översikt över de nationella minoriteterna, deras historia samt om hur filmen kan utgöra ett verktyg i undervisningen.
BACKGROUND: The advent of PD-1/PD-L1 inhibitors has revolutionized lung cancer treatment, necessitating accurate PD-L1 immunohistochemical (IHC) assessment. While standardized for formalin-fixed paraffin-embedded (FFPE) histological samples, PD-L1 testing on cytology remains challenging. This review aims to address the complexities of PD-L1 IHC in cytology, focusing on validation guidelines, quali
Svensk Kolinlagring och Lunds universitet (LUCSUS) samlade 19 personer för en workshop på Torsåker gård i syfte att diskutera styrmedel och strategier för att öka kolinlagringen i jordbruksmark, och hur dessa verktyg skulle kunna utformas för att stödja en omställning till ett socialt och ekologiskt hållbart matsystem. Deltagarna representerade olika delar och nivåer av matsystemet och bidrog med
Årligen upptäcks nya kärlväxter i Sverige. Det kan vara arter som etablerar sig i Sverige i klimatförändringarnas spår, som följer med internationella transporter, och inte minst trädgårdsrymlingar. Det finns flera skäl till att dokumentera dessa, inte minst för att förebygga spridning av invasiva arter. Biologiska museet i Lund tar emot belägg och listar här de arter som var nya för Sverige 2023.
We study an information design problem to reduce congestion in transportation networks. In presence of an uncertain network state, the central planner may sends private signals to the users, with the goal of steering the user equilibrium towards the system optimum flow. We consider private signals and provide sufficient conditions under which optimality may be achieved by information provision in
This is the first of three chapters (this chapter and Chapters 7 and 8) on diffusion MRI acquisition for tractography. For tractography, the acquisition is optimized for the estimation of fiber orientation. This chapter covers the creation of diffusion contrast. This is largely independent of the image encoding part of the MRI sequence, which is covered in Chapter 7. Unless explicitly stated, this
This is the second of three chapters on diffusion MRI acquisition for tractography. This chapter covers image formation, which is largely independent of the creation of diffusion contrast (Chapter 6). The Stejskal-Tanner diffusion experiments in the 1960s were bulk NMR measurements of diffusion; the addition of spatial localization, i.e., imaging, would follow decades later. The excitation and rea
To effectively navigate out of the climate crisis, a new interdisciplinary approach is needed to guide and facilitate research that integrates diverse understandings of how transitions evolve in intertwined social–environmental systems. The concept of tipping points, frequently used in the natural sciences and increasingly in the social sciences, can help elucidate processes underlying major socia
Aquaglyceroporins are channels that facilitate the flux of glycerol and water across lipid bilayers. Although structural information is available for several aquaglyceroporins, the details of how water and glycerol selectivity are maintained and how protons are excluded remain elusive. An approach to obtaining data on the hydrogen atom positions is to apply neutron macromolecular crystallography.
We study the Pauli operator in a 2-dimensional, connected domain with Neumann or Robin boundary condition. We prove a sharp lower bound on the number of negative eigenvalues reminiscent of the Aharonov-Casher formula. We apply this lower bound to obtain a new formula on the number of eigenvalues of the magnetic Neumann Laplacian in the semiclassical limit. Our approach relies on reduction to a bou
This study explores a collaborative project between various levels of public administration in southern Sweden, designed to encourage companies to adopt sustainable transportation practices. Conducted with the participation of researchers from Lund University, the project supports companies in developing and annually revising action plans that include specific sustainability goals, assigned respon
In this paper, we present a summary of fractal calculus and propose the use of Lagrange multipliers for both fractal calculus and fractal variational calculus with constraints. We examine the application of these methods across various branches of physics. By employing fractal variational calculus with constraints, we derive fundamental equations such as the fractal mechanical wave equation, the f
Avoiding severe global warming requires large-scale removals of atmospheric carbon dioxide. Forest regeneration offers cost-effective carbon removals, but annual rates vary substantially by location and forest age. Here we generate grid-level (~1-km2) growth curves for aboveground live carbon in naturally regrowing forests by combining 109,708 field estimates with 66 environmental covariates. Acro
In this paper, we present an experiment that shows conflicting findings from truth-value judgments and eye-tracking data for testing reference assignment of proper names. We argue that if eye-tracking is a more reliable method than truth-value judgment tasks, then our eye-tracking data provide stronger empirical support for Kripke’s causal-historical theory of reference for proper names. We also a
In a world where the concept of just-in-time has been lifted outside of the manu-facturing world and onto the market, the increasing demand of luxury wares like cars is accompanied only by tougher industrial conditions and no room for error. Loss of productivity and decrease in efficiency can be devastating to any manufac-turing company in today’s market climate. One of the largest causes of these
Researchers, from various academic departments, are increasingly undertaking studies of phenomena by way of practices considered to be within the sub-field of emotional geography. Emotional geographers, in an attempt to imbue research with the intensely subjective experiences of events and spaces, seek to uncover feelings by way of emotions, yet cautiously avoids the non-representational by workin
I den senaste versionen av kommunikationsprotokollet Transport Layer Security (TLS 1.3), introducerades en funktion som möjliggör att sessioner återupptas i ``zero round-trip time'' (översatt: noll tur- och returtid, förkortat 0-RTT) vilket innebär att snabbare uppkoppling är möjlig eftersom krypterad applikationsdata kan skickas redan med det första dataflödet från klient till server. FörThe latest version of the Transport Layer Security protocol (TLS 1.3) introduces a pre-shared key zero round-trip time (0-RTT) mode. This enables session resumption with no latency before the first application data can be sent, at the cost of losing forward secrecy and replay protection. There is high demand from Internet companies for this performance-enhancing feature, and some service providers
