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BACKGROUND: Intraperitoneal chemotherapy has an established role in the treatment of selected patients with colorectal peritoneal metastases. Oxaliplatin is highly suitable as a chemotherapeutic agent for hyperthermic intraperitoneal chemotherapy (HIPEC), but its use to date has been limited because of the morbidity caused by severe electrolyte and glycemic imbalances associated with 5% glucose as
In this paper, we present a study of Swedish inhabitants' preferences for distribution in three dimensions in the context of transport investments. Using choice experiments, we study the respondents' preferences for the distribution of benefits in the geographical, gender, and income dimension in relation to aggregate benefits. We find that they have quite strong preferences for equality in all di
Let M be a compact, connected C∞ manifold with a C∞ Riemannian metric or let M=Rn with Euclidean metric. Let g denote the metric. On M consider the 2×2 system of Schrödinger operators[TeX:] \[P=-h^{2}\Delta +V+h^{2}\mathcal{W},\qquadV=\left(\begin{array}[cc]v_{1}&0\\0&v_{2}\end{array}\right)\]where v1,v2∈C∞(M) are non-negative, and W is a C∞, first order formally selfadjoint differential o
PoxtA and OptrA are ATP binding cassette (ABC) proteins of the F subtype (ABCF). They confer resistance to oxazolidinone and phenicol antibiotics, such as linezolid and chloramphenicol, which stall translating ribosomes when certain amino acids are present at a defined position in the nascent polypeptide chain. These proteins are often encoded on mobile genetic elements, facilitating their rapid s
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There is a pressing need to capture and track subtle cognitive change at the preclinical stage of Alzheimer's disease (AD) rapidly, cost-effectively, and with high sensitivity. Concurrently, the landscape of digital cognitive assessment is rapidly evolving as technology advances, older adult tech-adoption increases, and external events (i.e., COVID-19) necessitate remote digital assessment. Here,
Camelina sativa (Camelina) is an oilseed crop that in recent years has gained importance due to its closeness to the plant model organism Arabidopsis thaliana (Arabidopsis), its low agronomical requirements, and the ability to grow under temperate conditions. To explore all the agronomical and biotechnological possibilities of this crop, it is important to evaluate the usability of the molecular p
Of concern are traveling wave solutions for the fractional Kadomtsev–Petviashvili (fKP) equation. The existence of periodically modulated solitary wave solutions is proved by dimension-breaking bifurcation. Moreover, the line solitary wave solutions and their transverse (in)stability are discussed. Analogous to the classical Kadmomtsev–Petviashvili (KP) equation, the fKP equation comes in two vers
Den antiamerikanska vänstern har fått en märklig ny sängkamrat efter Rysslands invasion av Ukraina: den ”realistiska” skolan inom internationella relationer, företrädd av den amerikanske professorn John Mearsheimer. Detta trots att realismen visat sig usel som prognosverktyg och att tron på den starkes rätt över den svage är något som annars brukar leda till protester – åtminstone mot USA, skriverDen antiamerikanska vänstern har fått en märklig ny sängkamrat efter Rysslands invasion av Ukraina: den ”realistiska” skolan inom internationella relationer, företrädd av den amerikanske professorn John Mearsheimer. Detta trots att realismen visat sig usel som prognosverktyg och att tron på den starkes rätt över den svage är något som annars brukar leda till protester – åtminstone mot USA, skriver
Over the last decades, dramatic improvements in combinatorialoptimisation algorithms have significantly impacted artificialintelligence, operations research, and other areas. These advances,however, are achieved through highly sophisticated algorithms that aredifficult to verify and prone to implementation errors that can causeincorrect results. A promising approach to detect wrong results is tous
This paper documents the development of a sustainable greenhouse system which incorporates a greenhouse, reverse electrodialysis (RED), reverse osmosis, and a dehumidification desalination system aiming to support water and energy self-sufficient agriculture in arid regions with a saline groundwater feed. The system is referred to as the sustainable greenhouse (SGH). The aim is to generate enough
Purpose: Gender dysphoria is commonly conceptualized as a mental disorder in gender-diverse people who do not identify with the gender assigned to them at birth. Direct support for well-being tends to be delegated to the field of mental health (MH), whereas speech-language pathology (SLP) practice is charged with modifying gender-diverse people's voice and communication in the belief that well-bei
The stability of relaxation techniques has been studied for strongly coupled fluid-structure interaction (FSI) with application to a cantilever immersed in channel flow. The fluid is governed by Navier–Stokes equations for incompressible flow condition using turbulence modeling, and the solid is governed by the equation of motion with compressible material modeling. The applied kinematic descripti
Research on the efficacy of hypnosis applications continues to grow, but there remain major gaps between the science and clinical practice. One challenge has been a lack of consensus on which applications of hypnosis are efficacious based on research evidence. In 2018, 6 major hypnosis organizations collaborated to form the Task Force for Establishing Efficacy Standards for Clinical Hypnosis. This
Urban flood damage leads to major costs for private house owners, insurance companies, and water and wastewater utilities. Analysis of flood damage claims can be used to improve the understanding of the details of flood damage characteristics and reasons for drainage system failures. However, few studies have used data of this kind to investigate urban flood characteristics. We examined 3113 damag
Joint time-frequency representations are important tools when estimating the instantaneous frequency. The widely used spectrogram is known to have poor energy localisation, which the reassignment method improves. However, the reassignment method is sensitive to noise. In this paper we present a multitaper reassigned spectrogram (MTRS) that is robust to noise and tailored to short duration transien
