Filetype
Purpose: Diabetic retinopathy is the most common eye complication in patients with diabetes. The purpose of this study is to identify genetic factors contributing to severe diabetic retinopathy. Methods: A genome-wide association approach was applied. In the Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS) datasets, cases of severe diabetic retinopathy were defined as type 2 d
This article examines how intensive care staff navigated the emotional and temporal complexities of the COVID-19 pandemic, drawing on qualitative data from two Swedish ICUs. Rather than treating emotional responses as secondary reactions to crisis, the analysis shows that emotions were deeply embedded in professional feeling rules, organizational hierarchies, and the poly-temporal unfolding of the
Populärvetenskaplig sammanfattning: Rassepautasjtjåkka är ett litet bergsmassiv beläget i norra Lappland. I massivet återfinns fyra stora nischer strax under glaciationsgränsen. Dessa nischer har en gång blivit uteroderade av glaciärer, men idag återfinns endast perenna snölegor i området. Skillnaden mellan en glaciär och en perenn snölega är att en glaciär har intern rörelse. En tjocklek på cirkaSince the mid 1970s the general retreating trend for glacier in Scandinavian have ceased and some glaciers have even started to advance. This is due to a more maritime influence on the climate, which means increased precipitation in winter and lower summer temperature. A more maritime climate can be said to be favourable for glacier growth. Under such climate conditions is it possible that new gla
Purpose The EPHOR-NIGHT cohort was established to investigate how night shift work influences biological pathways and chronic disease risk using a comprehensive working-life exposome approach, focusing on cardiometabolic, mental health, cognitive and biological ageing outcomes. Participant The cohort includes 937 workers aged 20–65 years (88%female), primarily from the healthcare sector (96%) in S
Background: Few longitudinal studies investigate predictors of substance use incidence among immigrants. The current study describes substance use disorders in immigrants to Sweden, focusing on drinking culture in the country of origin and socioeconomic status (SES), and how these intersect with generational status to influence risk. Methods: Using pseudonymized Swedish population registry data, w
Background: While discontinuation of COPD maintenance medication is a known problem, the proportion of patients with discontinuation and its geographical and sociodemographic distribution are so far unknown in Sweden. Therefore, we analyse this question by applying an innovative approach called multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA). Patients and Metho
Background: Digital breast tomosynthesis (DBT) is considered superior to digital mammography (DM) for women with dense breasts. Purpose: To identify differences in screening outcomes, including rates of recall, false-positive (FP) findings, biopsy, cancer detection rate, positive predictive value of recalls and biopsies, and histopathologic tumor characteristics by density using DBT combined with
Summary: Background: Diabetes mellitus (DM) is a risk factor for peripheral arterial disease (PAD). Indications for open surgery in infrainguinal intermittent claudication (IC) are limited, and reports are lacking regarding outcomes in DM patients. Study aims were to compare short and long-term effects on major adverse cardiovascular events (MACE), acute myocardial infarction (AMI), stroke, major
Introduction: Fast-track referral pathways for patients with nonspecific, serious symptoms have been implemented in several countries. Our objective was to analyze time intervals in the diagnostic routes of patients diagnosed with cancer at Sweden’s first Diagnostic Center (DC) for nonspecific symptoms and compare with time intervals of matched control patients. Methods: Adult patients with nonspe
Befolkningen växer och andelen som vill bo i städer ökar stadigt vilket skaparbehov av ny mark att bygga bostäder på. Tidigare har de flesta städer och orterutvecklats genom att växa utåt, vilket har lett till förlust av naturområden ochjordbruksmark och ökat beroendet av bilar. Att bygga staden inåt istället, så kallad förtätning, är numera en populär strategi för att minska bostadsbristen. I denThe proportion of people living in densely built up areas is gradually increasing,forcing cities to generate new land to build homes upon. In this process there is a risk for an inexplicit decrease of green space. The green features ofneighbourhoods help to create a supportive environment for health and physicalactivity, thus a reduction of greenness may reduce the general well-being in thepopulat
In this study, a novel macroporous composite biomaterial consisting of gelatin-hydroxyapatite-calcium sulphate for delivery of bone morphogenic protein-2 (rhBMP-2) and zoledronic acid (ZA) has been developed. The biomaterial scaffold has a porous structure and functionalization of the scaffold with rhBMP-2 induces osteogenic differentiation of MC3T3-e1 cells seen by a significant increase in bioch
The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors. One genetic possibility involves patients having mutations in multiple high-risk PC-related genes; however, no systematic examination has yet been conducted. We used next-generation sequenc
IL-5 is a Th2 cytokine which activates eosinophils and is suggested to have an atheroprotective role. Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to identify genetic variants associated with IL-5 concentrations and apply a Mendelian randomisation approach to assess IL-5 levels for causal effect on intima-media thickn
Ageing societies are facing major housing challenges. Understanding and addressing older adults' diverse housing needs and preferences are crucial. Having access to suitable and sustainable housing options can improve social cohesion, independence, health, and well-being. Participatory processes in housing development can enhance inclusion and democratic participation. This study uses Ramlösa Port
När forskare blickar ut i universum ser de överallt spåren av en stor mängd osynlig massa. Massan finns där men det går inte att se den. Ungefär 80% av all massa i universum beräknas bestå av denna "mörka materia". Det är som att mänskligheten står på stranden och blickar ut över havet utan att veta vad vatten är. I partikelfysik studeras universums minsta beståndsdelar, elementarpartiklarna, för The high event rate delivered by the Large Hadron Collider (LHC) provides experiments with opportunities for new discoveries as well as challenges related to the large amounts of data recorded. Overcoming this requires innovative techniques in the three topics of this thesis: Data acquisition, data analysis, and data compression.In the data taking period of 2015-2018, the ATLAS experiment received
Objective: To screen a general pediatric population for type 1 diabetes (T1D), celiac disease (CD), and autoimmune thyroid disease (AITD) after home capillary sampling. Methods: Swedish schoolchildren between 6–9 years and 13–16 years of age were invited to screening by taking a capillary sample at home. Samples were returned by mail and assessed for autoantibodies associated with T1D, CD, and AIT
HUMANISTISKA OCH TEOLOGISKA FAKULTETERNA PROTOKOLL 2021-02-17 kr. 8.30-9.30 AU-ledamot, prodekan AU-ledamot, doktorand AU-ledamot, prodekan AU-ledamot, dekanus AU-ledamot, student AUledamot, prodekan huvudskyddsombud studentrepresentant prefekt fakultetskoordinator Företagshälsovården arbetsmilj ösamordnare kanslichef ekonomichef chef Driftsenhet HT AUledamot, student 1(4) ffijxèõz LuNns UNIVERSIT
https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/arbetsmiljo/LSK_protokoll_2021.pdf - 2026-06-29
Popular Abstract in Swedish Den gynekologiska hälsokontrollen har medfört att incidensen av invasiv cervix-cancer kunnat halveras på 20 år i Sverige. Trots detta inträffar fortfarande mellan 5 - 600 nya fall av invasiv cervix-cancer årligen. Dessvärre tillhör en icke så litendel av dessa patienter tidigare cytologiskt kontrollerade kvinnor. Ralf Richard, New York, har på 70-talet ingående studera3,100 non-pregnant women and 85 pregnants were miniconized during the 15-year period ending 1994 . The outpatient procedure of minimal conization using a freehand-guided, high power 60W carbon dioxide laser focused to 0.1 mm in spot-size, giving high power density 165,000 W/cm2, produces single-piece tissue specimens for histological examination. The procedure is performed under local anaesthesia
