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Uncontrollable events such as adverse weather and volatile prices present considerable risks for arable farmers. Soil natural capital, which views the capacity of soil biodiversity to generate ecosystem services as a component of farm capital, could be important for the stability and resilience of arable production systems. We investigate therefore whether managing soil natural capital could be an

Asthma patients who continue to experience symptoms despite taking regular inhaled corticosteroids represent a management challenge. Leukotrienes play a key role in asthma pathophysiology, and since pro-inflammatory leukotrienes are poorly suppressed by corticosteroids it seems rational to add a leukotriene receptor antagonist (LTRA) when a low to moderate dose of inhaled corticosteroids does not

Objective: Metformin has been reported to reduce alpha-dicarbonyls, which are known to contribute to diabetic complications. It is unclear whether this is due to direct quenching of alpha-dicarbonyls or to an improvement in glycemic control. We therefore compared the effects of metformin versus repaglinide, an antihyperglycemic agent with an insulin-secreting mechanism, on the levels of the alpha-

In this study we describe the morphological and genetic analysis of the Drosophila mutant gurtelchen (gurt). gurt was identified by screening an EMS collection for novel mutations affecting visceral mesoderm development and was named after the distinct belt shaped visceral phenotype. Interestingly, determination of visceral cell identities and subsequent visceral myoblast fusion is not affected in

The success of breast cancer therapies targeting the human epidermal growth factor receptor-2 (HER2) is limited by the development of drug resistance by mechanisms including upregulation of HER3. Having reported that HER2 expression and resistance to HER2-targeted therapies can be regulated by Junctional Adhesion Molecule-A (JAM-A), this study investigated if JAM-A regulates HER3 expression. Expre

Assessing the relative contribution of Land Use and Cover Changes (LUCC) and climate changes on runoff still represents a great challenge for water resources management. This issue is particularly critical for the Upper Paraná River Basin (UPRB), one of the most important basins in South America and responsible for most of the production of food, ethanol, and electricity generation in Brazil. In t

The Earth system model EC-Earth3 for contributions to CMIP6 is documented here, with its flexible coupling framework, major model configurations, a methodology for ensuring the simulations are comparable across different high-performance computing (HPC) systems, and with the physical performance of base configurations over the historical period. The variety of possible configurations and sub-model

While many projects have demonstrated the potential of single Nature-based Solutions (NbS) to contribute to urban climate change adaptation, the challenge now lies in moving from demonstration projects to a full-scale deployment. The aim of this research is to assess the potential for a full-scale implementation of NbS in Malmö (Sweden), and the expected benefits and co-benefits. We developed six

The properties of iron (Fe) complexes and compounds in the environment influence several central processes, e.g., iron uptake, adsorption/desorption of contaminants and nutrients, and redox transformations, as well as the fate of of natural organic matter (NOM). It is thus important to characterize Fe species in environmental samples. Synchrotron-based extended X-ray absorption fine structure (EXA

Detective stories are a common part of our society today through literature and television, and the most famous detective of all is undoubtedly Sherlock Holmes. The Sherlock Holmes stories narrate several mysteries set in the late 19th to mid 20th century, and through the mysteries a large number of men and women are presented. During the late 19th century, the women’s movement for more equal righ

This thesis investigates the social structures and discourse behind a culture of free love in a rural community in Portugal called Tamera. It describes how emotions and communication regarding personal romantic and sexual relationship are dealt with, as well as the incentives behind creating such a culture. Throughout the analysis I describe the political theory and vision behind the project Tamer

The United States and the European Union operate under the similar design of a federal structure and their labor markets face similar tax discrimination challenges. Case law illustrates how the goal of a common market present in both unions is highly influential on the respective Courts and provides a flexible structure to protect individuals against discriminatory tax legislation. It is the centr

Agricultural soils contribute to human welfare through their generation of manifold ecosystem services such as food security, water quality and climate regulation, but these are degraded by common farming practices. We have developed a roadmap for evaluating the contribution of both private- and public-good ecosystem services generated by agricultural soils to societal welfare. The approach consid

PurposeThe reuse of timber building parts, when designing new buildings, has become a topic of increasing discussion as a proposed circular solution in support of sustainable development goals. Designers face the difficulty of identifying and applying different design strategies for reuse due to multiple definitions, which are used interchangeably. The purpose of this study is to propose a taxonom