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Context: Several drugs are approved and available for the treatment of lower urinary tract symptoms (LUTS) in men and women. However, the vast majority of available data, upon which the approval and recommendation in guidelines are based, considered only the role of the monotherapies and did not evaluate possible combination therapies. Objective: This systematic review analyzes the efficacy and ad
Background: Criteria for electrocardiographic detection of acute myocardial ischemia recommended by the Consensus Document of ESC/ACCF/AHA/WHF consist of two parts: The ST elevation myocardial infarction (STEMI) criteria based on ST elevation (ST↑) in 10 pairs of contiguous leads and the other on ST depression (ST↓) in the same 10 contiguous pairs. Our aim was to assess sensitivity (SE) and specif
In this work, we investigated muonic atoms and molecules from a quantum chemist's viewpoint by incorporating muons in the CASSCF model. With the aim of predicting muonic X-ray energies, primitive muonic basis sets were developed for a selection of elements. The basis sets were then used in CASSCF calculations of various atoms and molecules to calculate muonic excited states. We described the influ
GCMs (general circulation models) are main tools for generating climate projections for climate change research in hydrology and water resources. Accordingly, evaluating the performance of these models in simulating future climate is very important for choice of proper models. In this study, performance of 20 Coupled Model Intercomparison Project Phase 5 (CMIP5) model series was assessed using a t
A framework is proposed for modelling the uncertainty in the measurement processes constituting the dosimetry chain that are involved in internal absorbed dose calculations. The starting point is the basic model for absorbed dose in a site of interest as the product of the cumulated activity and a dose factor. In turn, the cumulated activity is given by the area under a time–activity curve derived
Background: Reproducible quantification of drug transporter protein expression in tissues is important for predicting transporter mediated drug disposition. Many mass-spectrometry based transporter protein quantification methods result in high variability of the estimated transporter quantities. Therefore, we aimed to evaluate and optimize mass spectrometry-based quantification method for drug tra
In the last decades, nanotechnology has played a key role in the electrochemical biosensor development based on the mediated and direct electrochemical communication between the biorecognition elements and the electrode surface. In particular, graphene and 2D-like nanomaterials (e.g., boron nitride nanosheets, graphitic carbon nitride (g-C3N4) nanosheets, and various transition metal dichalcogenid
This paper elucidates a disciplinary context for an emergent buildingtype dubbed Accessory Dwelling Unit, or ADU. Today, ADU developmentsadd density to metropolitan Los Angeles by undermining the low densityprinciples of single-family residential zoning. Surfacing withinthe jurisdiction formally known as the City of Los Angeles, the ADUsupplements city planning in the transformation of suburbia. T
A reduction in the number of postoperative bed days for patients who underwent appendectomy led to a study of changes in hospital costs of appendectomies for the years 1955, and 1965, and 1975. No significant changes were found in the total hospital costs. However, the postoperative costs decreased by 36 percent from 1955 to 1975 due to a decrease in the mean duration of hospital stay. During the
The effect of loperamide on faecal control after Stephens rectoplasty for high imperforate anus was studied in eight patients more than 8 years after surgery. Clinical assessment and anorectal manometry were performed before and after administration of loperamide for 6 to 8 weeks. Decreased faecal soiling was noted in seven of the eight cases. Obstipation forced two patients to stop the medication
In recent years, there has been an increasing interest in innovation studies towards grand challenges, and in how demand-side policy instruments can supplement traditional supply-side policy measures. To contribute to an improved understanding of how demand-side policy requires new governance responses, this article presents a case study of trialling assisted living technologies to address the gra
Very strong Sc i lines have recently been found in cool M giants in the Nuclear Star Cluster (NSC) in the Galactic center. Interpreting these as anomalously high scandium abundances in the Galactic center would imply a unique enhancement signature and chemical evolution history for NSCs, and a potential test for models of chemical enrichment in these objects. We present high resolution K-band spec
This chapter presents a brief summary and state-of-the-art overview of computational methods in heat transfer equipment, that is, computational fluid dynamics (CFD) methods for thermal problems and turbulence modeling for single-phase applications in the design, research, and development of heat exchangers. Some examples for real heat exchangers are shown to demonstrate how CFD methods can be used
En kvarstående abdominell rektusmuskeldiastas hos kvinnor efter förlossning är vanlig och kan medföra försämrad bålmuskelfunktion och hos en del patienter avsevärt nedsatt livskvalitet.Den vetenskapliga evidensen för val av behandling av abdominell rektusmuskeldiastas är svag. Fysioterapi med bålstabiliserande träning bör vara förstahandsval.Hos en liten grupp med mer uttalade besvär där fysiotera
