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BACKGROUND: By gating image acquisition in myocardial perfusion SPECT (MPS) to ECG, left ventricular (LV) volumes and function can be determined. Several previous studies have shown that existing MPS software packages underestimate LV volumes compared to cardiac magnetic resonance (CMR). The aim of this study was therefore to develop a new LV segmentation algorithm for gated MPS using CMR as refer
Overproduction of membrane proteins can be a cumbersome task, particularly if high yields are desirable. NADH:quinone oxidoreductase (complex I) contains several very large membrane-spanning protein subunits that hitherto have been impossible to express individually in any appreciable amounts in Escherichia coli. The polypeptides contain no prosthetic groups and are poorly antigenic, making optimi
This research presents the modeling of the anaerobic digestion of cane-molasses vinasse, hereby extending the Anaerobic Digestion Model No. 1 with sulfate reduction for a very high strength and sulfate rich wastewater. Based on a sensitivity analysis, four parameters of the original ADM1 and all sulfate reduction parameters were calibrated. Although some deviations were observed between model pred
A search for new charged massive gauge bosons, called W', is performed with the ATLAS detector at the LHC, in proton-proton collisions at a centre-of-mass energy of root s = 8 TeV, using a dataset corresponding to an integrated luminosity of 20.3 fb(-1). This analysis searches for W' bosons in the W' -> t (b) over tilde decay channel in final states with electrons or muons, using a multivariate me
Background: Many patients with aggressive B-cell lymphomas and high clinical risk score still die of lymphoma after conventional R-CHOP chemoimmunotherapy. We hypothesized that intensified chemoimmunotherapy including systemic central nervous system (CNS) prophylaxis improves outcome and reduces the incidence of CNS-related events. Patients and methods: Inclusion criteria were age 18-65 years, pri
Intellectual property is a very important type of asset in today’s business world. Since business in the Western World grows increasingly based and dependent on know-how and technological development, intangible assets such as trademarks, copyrights and patents plausibly represent greater economic value to economic actors here than other, physical, assets do. Although it is comparatively unknown
Just nu finns det en möjlighet för politikerna att lägga om stadsplaneringen så att det blir möjligt att nå FN:s hållbarhetsmål. Det skriver åtta forskare som arbetar med miljö- och hälsofrågor.
It is frustrating for every reasonable human being to observe scenes of exploitation around the world in respect of children, because of their either naivety or vulnerability. It is unacceptable that still in the 21st century, children do not benefit from the protection, attention and love they deserve. An estimated 300 million children worldwide are subject to violence, exploitation and abuse inc
By 2050, seven billion people will be living in cities. In 2020 itself, these cities dumped a whopping 29 trillion tonnes of carbon dioxide into the atmosphere. This carbon dioxide along with other greenhouse gases poses a serious health hazard. It also manifests as extreme weather events, leading to the loss of lives, livelihoods, assets, and social wellbeing.Given the significant impact that cit
This study explores the relative interest in various mental-health topics among adolescents. The results of this study will be used to develop relevant information material for the age-group and for interested mental-health practitioners as well as teachers. The participating adolescents were between 13-19 (N = 2058) recruited through social media. In the sample 922 participants attended lower sec
Aim To examine the associations between individual- and disease-related factors and the odds of reaching a clinically relevant pain reduction in people with knee and/or hip osteoarthritis (OA) who underwent a first-line self-management program. Materials and methods An observational registry-based study including people with knee (n = 18,871) and hip (n = 7,767) OA who participated in a self-manag
A search for dark matter produced in association with a Higgs boson decaying to b-quarks is performed using pp collisions at a centre-of-mass energy of √s=13 TeV. The dataset has an integrated luminosity of 79.8 fb−1 and was recorded with the ATLAS detector at the Large Hadron Collider. Selected collision events comprise large missing transverse momentum and either two b-tagged small radius jets o
A search for an invisibly decaying Higgs boson or dark matter candidates produced in association with a leptonically decaying Z boson in proton–proton collisions at s=13 TeV is presented. This search uses 36.1 fb−1 of data collected by the ATLAS experiment at the Large Hadron Collider. No significant deviation from the expectation of the Standard Model backgrounds is observed. Assuming the Standar
Landscape, process and economy in the bloomery iron production during AD 400–1000 are all integrated in this paper initiated by an archaeological exca-vation of a bloomery site in Motala in Östergötland, southeast Sweden. This site is one among other contemporaneous sites with similar features, such as long-term iron production and a location in the landscape within easy reach of communication rou
Socioeconomic status (SES) differences in health are well known. Both material and psychosocial hypotheses regarding these SES differences have been forwarded. Social capital (trust, social participation) may be seen as a contextual and social extension of this debate with access to healthcare as one of the four hypothesized mechanisms between high social capital and health. This thesis investigatSocioeconomic status (SES) differences in health are well known. Both material and psychosocial hypotheses regarding these SES differences have been forwarded. Social capital (trust, social participation) may be seen as a contextual and social extension of this debate with access to healthcare as one of the four hypothesized mechanisms between high social capital and health. This thesis investigat
BACKGROUND: The dual-mobility acetabular cup (DMC) has an additional bearing consisting of a mobile polyethylene component between the prosthetic head and the outer metal shell. This design has gained popularity in revision total hip arthroplasty (THA) and in primary treatment of femoral neck fractures with the anticipation of a reduced risk of THA instability. Our primary aim was to evaluate the
Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. Previous work fro
