Filetype
Ribosomal protein S19 (RP S19) possesses ribosomal function as RP S19 monomer and extraribosomal function as cross-linked RP S19 oligomers which function as a ligand of the complement 5a (C5a) receptor (CD88). We have generated a Gln137Glu-RP S19 knock-in (KI) mouse, which is shown to possess the weakened extraribosomal function of RP S19. Because whether the extraribosomal function of RP S19 has
Aim: Respiratory distress syndrome (RDS) is a major cause of mortality and morbidity in premature infants. By the time symptoms appear, it may already be too late to prevent a severe course, with bronchopulmonary dysplasia or mortality. We aimed to develop a rapid test of lung maturity for targeting surfactant supplementation. Methods: Concentrations of the most surface-active lung phospholipid di
The latest study of the millimeter wave (mmWave) phased array in user device (UE) for 5G communication is presented in this paper. Particularly, the body effect on the phased array in a UE/mobile terminal at 15 GHz is investigated with the 3D measured data. Its impact on the recently introduced parameter for phased array in mobile terminal, the total scanning pattern, body loss and the coverage ef
The author spent seven years teaching and tutoring basic media use to liberal arts students. During this time, the author noted that liberal arts students differ in their use of technology, both in basic technical comprehension and computer skills levels, as compared to technical and computer science students. Different pedagogical approaches for the liberal arts students for the period of 2003-20
Increasing evidence supports the benefit of identifying BRCA1 and BRCA2 germline mutations in early breast cancer. Selection of patients for genetic testing is based on defined criteria taking individual and family history related factors into account. It is important to make a distinction between efficacy and effectiveness of BRCA testing criteria. Efficacy can be defined as the performance under
Aim: To estimate the effects of targeted elimination of environmental barriers (EB) in the ordinary housing stock in Sweden, and to explore the estimated effects on accessibility at a population level in relation to (a) residents with different functional profiles, (b) different housing types and (c) building periods. Method: Data on dwellings from existing Swedish research databases were utilized
The present article elaborates on struggles over the inclusion and exclusion of undocumented children and young people in the Swedish school system. Through conducting an in-depth case study on the issue of access to school in the city of Malmö in Sweden, our analysis demonstrates how the right to education for undocumented migrant children is subject to a process of struggle between divergent dis
FeCo nanoparticles exsolved from Co-doped Sm0.9FeO3 nanofibers with abundant oxygen vacancies (Vos) are proposed as an efficient electrocatalyst to promote nitrate reduction reaction (NITRR). Such catalyst achieves a maximum Faradaic efficiency (FE) of 90.3 % and a large NH3 yield of 17.2 mg h−1 mg−1cat. at a negatively shifted potential of −0.9 V in 0.1 M PBS with 0.1 M NaNO3, and the alloy nanop
India has positioned itself as a leader in transitioning its energy sector to renewable sources, with ambitious targets and policies in place. Large-scale grid-integrated renewable energy plants have been identified as the most efficient option. Scholarly arguments differ regarding the impacts of renewables-led transitions, with some emphasizing positive environmental, economic, and social outcome
Oestrogen receptor alpha (ER; gene symbol ESR1) is the most important prognostic and treatment-predictive biomarker in breast cancer. Drugs targeting oestrogen and ER for endocrine therapy of breast cancer include aromatase inhibitors, the selective ER modulator tamoxifen and the selective ER degrader fulvestrant. Tumours can develop resistance to endocrine therapy through several mechanisms, whic
Background: Infants in the neonatal intensive care unit (NICU) are subjected to different types of stress, including sounds of high intensity. The sound levels in NICUs often exceed the maximum acceptable level recommended by the American Academy of Pediatrics, which is 45 decibels (dB). Hearing impairment is diagnosed in 2% to 10% of preterm infants compared to only 0.1% of the general paediatric
Precise epitope determination of therapeutic antibodies is of great value as it allows for further comprehension of mechanism of action, therapeutic responsiveness prediction, avoidance of unwanted cross reactivity, and vaccine design. The golden standard for discontinuous epitope determination is the laborious X-ray crystallography method. Here, we present a combinatorial method for rapid mapping
Utilizing green hydrogen produced by water electrolysis offers a viable strategy to mitigate the global energy crisis. In the present work, a high-performance, readily synthesized, and cost-effective anion exchange membrane (AEM) for alkaline water electrolyzers has been developed and studied. Glycidyl trimethyl ammonium chloride (GTA) was grafted onto poly(oxindole biphenylene) (POB) through
Generalist plant-feeding insects are characterised by a broad host repertoire that can comprise several families or even different orders of plants. The genetic and physiological mechanisms underlying the use of such a wide host range are still not fully understood. Earlier studies indicate that the consumption of different host plants is associated with host-specific gene expression profiles. It
Many services have become digitized in society, including health services. Although there are many advantages to eHealth services, some segments of the population cannot reap those benefits. Objectives: This study aimed to: 1- describe how people with intellectual disability use the internet in Sweden; and 2- understand the nature of the contextual and personal barriers these users face when tryin
Climate change and land degradation menace ecosystem sustainability. This study assessed the effectiveness of integrating nature-based solutions (NBSs); soil and water conservation techniques, agroforestry, and reforestation, to mitigate these impacts. Focusing on carbon storage and sediment retention at the watershed level (Sidi Barrak), the InVEST model quantified changes from 1990 to 2050 under
Breast cancer has a profound affect on society. The survival for women in low- and middle-income countries (LMICs) is poor compared to in high-income countries (HICs). The lack of timely diagnosis is one of the main factors contributing to the poor outcomes for women in LMICs. Point-of-care ultrasound (POCUS) combined with a deep learning (DL) classification network could potentially be a suitable
