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Neurogenin 2 (Ngn2) is a proneural gene involved in neuronal differentiation and subtype specification in various regions of the nervous system. In the ventral midbrain, Ngn2 is expressed in a spatiotemporal pattern that correlates with the generation of mesencephalic dopaminergic (mesDA) neurons. We show here that lack of Ngn2 impairs the development of mesDA neurons, such that less than half of
The aim of the study was to determine how significance indicators assigned to different Web page elements (internal metadata, title, headings, and main text) influence automated classification. The data collection that was used comprised 1000 Web pages in engineering, to which Engineering Information classes had been manually assigned. The significance indicators were derived using several differe
The soluble form of the urokinase receptor, suPAR, has been suggested as a novel biomarker of low-grade inflammation. Activation of the immune system has been proposed to contribute to the development of depression and suicidal behavior. In order to identify depressed and suicidal individuals who could benefit from an anti-inflammatory treatment, a reliable biomarker of low-grade inflammation is v
A critical edition of a hymn of the Epiphany (inc. "Maria candens lilium") in the manuscript AM 76, 8o of the Arnemagnæan collection, University of Copenhagen. The text has no known parallels and is in a corrupt state. Conjectures and interpretations are offered, as well as a translation of a tentatively emendated textual shape.
Labour and employment law, industrial relations in Sweden
En redogörelse för och diskussion av debattklimatet (olika positioner) i Saudiarabien mot bakgrund av terrorvågen i början av 2000-talet.
The volume analyzes the reasons behind, and consequences of, the growing involvement of transnational actors in established international institutions. It provides comparative analyses of varying international organizations and issue-areas. Combining normative democratic theory and empirical research, it offers innovative interpretations of the democratic legitimacy of current arrangemants.
Artikeln diskutera konservatismens etos som en specifik mänsklig grundhållning. Fyra aspekter lyfts fram: 1. Avsked från det principiella. 2. Anknytning till det redan förefintliga. 3. En pluralistisk etik. 4. En institutionell etik.
Accessibility throughout society has been gaining interest at the international as well as the national level. According to Swedish legislation, public environments should be accessible to all citizens by the year 2010. This paper focuses on older pedestrians, and aims at investigating how accessibility is dealt with and carried out in the municipal process of traffic planning: “accessibility in p
Context: The questions of how many individuals and how much time to use for a single testing task are critical in software verification and validation. In software review and usability evaluation contexts, positive effects of using multiple individuals for a task have been found, but software testing has not been studied from this viewpoint. Objective: We study how adding individuals and imposing
The galectins are known to be able to recognize and cross-link beta-D-galactopyranoside-containing glycoconjugates as a result of presenting multiple binding sites. This review summarizes efforts in our group for the last ten years towards low-molecular weight chemically modified carbohydrate derivatives. In addition to providing an avenue for improved affinity and galectin-selectivity, we have fo
Mesenchymal stem cells (MSC) have not only been implicated in the development of lung diseases, but they have also been proposed as a future cell-based therapy for lung diseases. However, the cellular identity of the primary MSC in human lung tissues has not yet been reported. This study therefore aimed to identify and characterise the 'bona fide' MSC in human lungs and to investigate if the MSC n
Bacteria appeared on the Earth millions years before us and human evolution was triggered by the constant presence of pathogenic and symbiotic microorganisms in our surroundings. Interplay occurred between higher organism and microbial consortia residing in the host organs and on the epithelial surfaces; another natural space of bacteria human interaction is the indoor environment where we spend t
The dynamic range is an important quantity used to describe an image sensor. Wide/High/Extended dynamic range is often brought forward as an important feature to compare one device to another. The dynamic range of an image sensor is normally given as a single number, which is often insufficient since a single number will not fully describe the dynamic capabilities of the sensor. A camera is ideall
The DEK oncogene is highly expressed in cells from most human tissues and overexpressed in a large and growing number of cancers. It also fuses with the NUP214 gene to form the DEK-NUP214 fusion gene in a subset of acute myeloid leukemia. Originally characterized as a member of this translocation, DEK has since been implicated in epigenetic and transcriptional regulation but its role in these proc
