Filetype
Objective: This study examined whether previously reported results, indicating that prostate-specific antigen (PSA) screening can reduce prostate cancer (PC) mortality regardless of sociodemographic inequality, could be corroborated in an 18 year follow-up. Materials and methods: In 1994, 20,000 men aged 50–64 years were randomized from the Göteborg population register to PSA screening or control
We use crystal-phase tuning during epitaxial growth of InAs nanowires to create quantum dots with very strong confinement. A set of gate electrodes are used to reproducibly split the quantum dots into even smaller pairs for which we can control the populations down to the last electron. The double quantum dots, which are parallel-coupled to source and drain, show clear and stable odd-even level pa
We develop a coupled electronic charge and photon transport simulation model to allow for deeper analysis of our recent experimental studies of intracavity double diode structures (DDSs). The studied structures consist of optically coupled AlGaAs/GaAs double heterojunction light emitting diode (LED) and GaAs p–n-homojunction photodiode (PD) structure, integrated as a single semiconductor device. T
Semiconductor nanowire arrays are a promising candidate for next generation solar cells due to enhanced absorption and reduced material consumption. However, to optimize their performance, time consuming three-dimensional (3D) opto-electronics modeling is usually performed. Here, we develop an accurate one-dimensional (1D) modeling method for the analysis. The 1D modeling is about 400 times faster
Objective: To determine the level of agreement of disease flare severity (distinguishing severe, moderate, and mild flare and persistent disease activity) in a large paper-patient exercise involving 988 individual cases of systemic lupus erythematosus. Methods: A total of 988 individual lupus case histories were assessed by 3 individual physicians. Complete agreement about the degree of flare (or
Many B-cell neoplasms are associated with autoimmune diseases (AIDs) but most evidence is based on a personal rather than a family history of AIDs. Here we calculated risks for non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL) and multiple myeloma (MM) when family members were diagnosed with any of 44 different AIDs, or, independently, risk for AIDs when family members were diagnosed with a neopla
Mechanical forces exists in many cellular processes, including cell proliferation, migration, rearrangement and differentiation. The transformation of cancer cells from normal cells, cancer metastasis and cell rearrangement during morphogenesis all involve changes in cellular mechanical forces. Although there are some studies about normal cell and cancer cell force measurements, a direct compariso
Semiconductor nanowires have great potential for realizing broadband photodetectors monolithically integrated with silicon. However, the spectral range of such detectors has so far been limited to selected regions in the ultraviolet, visible, and near-infrared regions. Here, we report on the first intersubband nanowire heterostructure array photodetectors exhibiting a spectrally resolved photoresp
Background: In patients with systemic lupus erythematosus (SLE) there is no serological test that will reliably distinguish neuropsychiatric (NP) events due to active SLE from those due to other causes. Previously we showed that serum levels of nitrated nucleosomes (NN) were elevated in a small number of patients with NPSLE. Here we measured serum NN in samples from a larger population of patients
We studied the association between neighborhood socioeconomic status (SES) and incidence of coronary heart disease (CHD) or ischemic stroke in the total population and in full- and half-siblings to determine whether these associations are causal or a result from familial confounding. Data were retrieved from nationwide Swedish registers containing individual clinical data linked to neighborhood of
The photothermoelectric (PTE) effect uses nonuniform absorption of light to produce a voltage via the Seebeck effect and is of interest for optical sensing and solar-to-electric energy conversion. However, the utility of PTE devices reported to date has been limited by the need to use a tightly focused laser spot to achieve the required, nonuniform illumination and by their dependence upon the See
Immunoglobulin light chain (AL) amyloidosis is characterized by tissue deposition of amyloid fibers derived from immunoglobulin light chain. AL amyloidosis and multiple myeloma (MM) originate from monoclonal gammopathy of undetermined significance. We wanted to characterize germline susceptibility to AL amyloidosis using a genome-wide association study (GWAS) on 1229 AL amyloidosis patients from G
De svenska riktade ränteavdragsbegränsningsreglerna infördes år 2009 i syfte att förhindra oönskad skatteplanering där den svenska skattebasen urholkas genom ränteupplägg med lån mellan bolag inom samma intressegemenskap. Regelverket återfinns numera i 24 kap. 18–20 §§ IL och begränsar avdragsrät-ten för räntekostnaderna på koncerninterna lån. Regelverket ändrades först år 2013 och sedan igen år 2The Swedish targeted interest deduction rules were introduced in 2009, aim-ing to prevent unwanted tax planning that erodes the Swedish tax base through interest schemes involving loans between intra-group companies. The rules are now located in Chapter 24, Sections 18–20 of the Income Tax Act (ITA) and limit the right to deduct interest costs on intra-group loans. The rules were modified in 2013,
The objective of this thesis is to provide answers to how a method can be designed to gain better knowledge of how collaboration looks between different critical societal activities in a preparing and preventive stage related to the management of transboundary risks. The designed method consists of two parts; a technique for data acquisition, and a method for data analysis. In order to evaluate th
Increasing climate change is causing a rise in natural disasters. One of the most common natural disasters in Sweden is flooding. Vulnerability is increasing due to urbanization and the removal of green spaces in Swedish cities. In the acute phase of a flooding, the municipal Fire and Rescue Services (FRS) are generally first to respond. In this thesis, the FRS’ management of flooding is reviewed
The aim of this thesis is to study the flammability and fire spread for textile membranes for weather protection. This thesis includes literature studies to determine current standards and recommendations available. Main focus however have been on the European classification system EN 13501-1 and construction site safety. Two types of experimental tests have been done, cone calorimeter test and te
Antalet rättsfall gällande oönskad publicering och spridning av andra människors privata material på Internet har ökat betydligt de senaste åren, med de s.k. Instagramupploppen 2012 som en sorts uppmärksamhetskulmen. Inget svenskt samlingsnamn som passar i alla dylika sammanhang har uppkommit och även om specifika detaljer skiljer sig åt från fall till fall, förefaller ärekränkningar förekomma somThe legal cases concerning unwanted online publishing of private material have experienced a significant rise in the last few years peaking around 2012 in Sweden, with initial assiduities around the issue being brought about by the “Instagram riots”. Up to this day, there is yet to be a collective term to entirely encompass these cases, and although the specific details differ between each case, t
Female survivors of childhood central nervous system (CNS) tumors experience an increased risk of infertility and various pregnancy complications. We aimed to explore whether the incidence of inguinal hernia could be higher in offspring of female CNS tumor survivors as compared to the general population. Girls who were younger than 15 years of age and diagnosed with CNS tumors between 1958 and 201
