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Background: Under inflammatory conditions, T cell-dependent (TD) protein antigens induce proinflammatory T-and B-cell responses. In contrast, tolerance induction by TD antigens without costimulation triggers the development of regulatory T cells. Under both conditions, IgG antibodies are generated, but whether they have different immunoregulatory functions remains elusive. Objective: It was shown

With cross-border ecommerce transactions growing increasingly common in 2026, retailers struggle to ensure that their websites persuade members of foreign cultures to make purchases. This study examines a specific example of this phenomenon, in which Danish ecommerce platforms attempt to encourage purchases among customers from the USA. Ethnographic methodological practices are employed, including

Emission source functions are extracted from correlation functions constructed from charged pions produced at midrapidity in Au+Au collisions at s(NN)=200 GeV. The source parameters extracted from these functions at low k(T) give first indications of a long tail for the pion emission source. The source extension cannot be explained solely by simple kinematic considerations. The possible role of a

Very intense neutrino beams and large neutrino detectors will be needed in order to enable the discovery of CP violation in the leptonic sector. We propose to use the proton linac of the European Spoliation Source currently under construction in Lund, Sweden, to deliver, in parallel with the spoliation neutron production, a very intense, cost effective and high performance neutrino beam. The basel

Introduction People with anterior cruciate ligament (ACL) reconstruction (ACLR) are at high risk of sustaining a graft rupture and/or contra-lateral ACL injury. The main factors that may predispose individuals for subsequent ACL injuries are, however, not established. To reduce the risk of reinjuries, it is of particular interest to identify modifiable risk-factors, for instance, those related to

Human cathelicidin antimicrobial protein hCAP18/LL-37 is an effector molecule of the nonspecific innate immune system. hCAP18/LL-37 is present in leukocytes and is expressed in skin and other epithelia, where it is upregulated in association with inflammation and injury. In addition, antimicrobial proteins including cathelicidins have been proposed to play a role in the nonspecific defense against

Trade and World Power: A Time-Space Appropriation Assessment of an 18th Century Swedish-Chinese-Spanish(-American) Trade Exchange Was China rather than Europe the center of the early modern world system, as claimed by so-called new world historians such as Kenneth Pomeranz and Andre Gunder Frank? Can structural position within the hierarchy of the world system be revealed through assessment of ec

This thesis is dedicated to the design and analysis of superconductingelliptical cavities. Elliptical cavities play a central role in modern particle ac-celerators due to their high efficiency. After an introduction to the EuropeanSpallation Source project, the thesis goes through the design of the medium-βcavity. The RF design of the inner cell and end cell are presented in sequencein paper I . T

We present a 200 kHz XUV source driven by an optical parametric chirped pulse amplification system. The advantage for photoemission electron microscopy of this high-repetition rate will be discussed.

Building the European Spallation Source (ESS), the most powerful neutron source in the world, requires significant technological advances at most fronts of instrument component design. Detectors are not an exception. The existing implementations at current neutron scattering facilities are at their performance limits and sometimes barely cover the scientific needs. At full operation the ESS will y

Design science research is an essential part of IS research since the field should not only try to understand how the world is, but also how to change it. We argue that the aim of IS design science research should be to develop practical knowledge not only for the design of novel information technology (IT), but also for IS governance and management. Whereas at least some methodological support ex

The European Spallation Source (ESS) linac will consist of three families of superconducting RE cavities to accelerate protons to a final beam energy of 2.5 GeV for collision with the target. Beam induced HOMs in these cavities may drive the beam unstable and increase the cryogenic load, severely limiting the operation of the linac. The effect of these modes on the beam quality is investigated in

This work is aimed at presenting a design for the proposed HIBEAM beamline which seeks to perform neutron oscillation measurements at the European Spallation Source (ESS). The design is informed by beamline simulations performed with PHITS 3.33 and detector simulations performed with both PHITS and Geant4 11.2. The shielding, consisting of 45 cm of steel and 85 cm of heavy concrete at its thickest

We investigate the enrichment patterns of several delivery scenarios of the volatiles to the atmospheres of ice giants, having in mind that the only well constrained determination made remotely, namely the carbon abundance measurement, suggests that their envelopes possess highly supersolar metallicities, i.e., close to two orders of magnitude above that of the protosolar nebula. In the framework

ODIN (Optical and Diffraction Imaging with Neutrons) is a general purpose imaging in- strument under construction at the European Spallation Source (ESS). The instrument will provide the scientific community with a wide array of neutron imaging techniques, including neutron tomography. Coupled with an integrated X-ray source, the instrument will feature multi-modal capabilities. The complementary

Dark matter remains a largely elusive phenomenon, particularly its composition. Several candidate particles have been proposed, including axions and axion-like particles (ALPs). Detection of axions and ALPs have been attempted but none so far have yielded positive results. The High Intensity Baryon Extraction and Measurement instrument (HIBEAM) at the European Spallation Source (ESS) will be used