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The present minireview of the place of cystatin C in clinical medicine emphasizes, and discuss the evidence, that cystatin C-based GFR-estimating equations do not require the use of vague terms like race and sex, that cystatin C-based GFR-esti mating equations are useful for both children and adults, including the elderly, that the best GFR-estimation requires simultaneous use of both cystatin C-

Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune processes and β-cell dysfunction are known to occur in type 1 diabetes, a complete understanding of the cell-to-cell interactions that support pancreatic function is still lacking. To characterize the pancreatic endocrine compartment, we stu

Objectives: To find variables associated with outcome following thrombolytic treatment for acute lower limb ischemia. Design: Re-analysis of a prospective multicentre study. Material and methods: One hundred and twenty-one patients with acute lower limb ischemia previously included in a randomised study comparing high- with low-dose thrombolysis were re-analysed ignoring the mode of lytic treatmen

There is compelling evidence to suggest that estrogen administration to women of climacteric age reduces subsequent myocardial infarction by some 50%. Accumulating data also suggests estrogens confer substantial protection from stroke. Given this rationale, it is prudent to suggest to regulatory bodies that estrogen treatment would have this indication. Estrogens have other well-defined, and less

BACKGROUND: Elevated plasma levels of heparin-binding protein (HBP) are associated with risk of organ dysfunction and mortality in sepsis, but little is known about causality and mechanisms of action of HBP. The objective of the present study was to test the hypothesis that HBP is a key mediator of the increased endothelial permeability observed in sepsis and to test potential treatments that inhi

Within the circular economy, alternatives to fast-fashion include second-hand clothing consumption. The narratives surrounding second-hand clothing have shifted from the stigma of old, dirty, smelly clothing to trendy, sustainable, and bargain items. The environmental benefits of second-hand are realised through the increased use-intensity and avoided production of new garments. However, these ben

Purpose: The aim of this paper is to find out how the PMM system can be used to remain resilient to a change in the environment and so continue to provide appropriate guidance to managers in real time. Methodology: The paper is based on a qualitative research method with primarily an abductive approach to derive insight about a PMM system’s use to remain resilient to a change in the environment.

Halvledarindustrin har en form av immaterialrätter avsedd särskilt för dem: Kretsmönsterrätter. Dessa introducerades i USA 1984 i syfte att skydda den amerikanska halvledarindustrin från konkurrens från östra Asien, huvudsakligen Japan. Den ersatte principen om nationell behandling med den materiella ömsesidighetsprincipen, som är normen inom immaterialrätt. Detta tillät USA att tvinga andra ländeThe semiconductor industry has a sui generis IP type dedicated to it: the semiconductor topography right. This right was introduced in 1984 with the purpose of protecting the U.S. semiconductor industry from East Asian, mainly Japanese, competition. It replaced the principle of treatment on a national basis that is the norm in IP law with one of material reciprocity, which allowed the U.S. to stro

This research investigates global adoption and suitability of phased evacuation strategies in multi-purpose residential buildings, blending a review of 33 codes and standards in 11 nations with simulation-based analysis of 30 phased evacuation scenarios. Findings from the review reveal a varied level of importance of phased evacuation worldwide, with Europe, particularly the United Kingdom, showin

The performed study is a qualitative case study of the company Business Sweden. An inductive research approach has been used where we started by observing Business Sweden and subsequently applied suitable theories. The aim with the paper is to describe and analyze the aspects of management control in a multinational hybrid organization, by observing the process of centralizing the responsibility o

Drowning is the second global leading cause of unintentional injury death for children ages 1 to 14 years, and the fifth leading cause for people of all ages (excluding flood disasters and water transport incidents). Why is the risk of drowning so high? It is important to investigate existing situation: what are the reasons that create a danger, is there a main risk group, how the risk of drownin

When live theatre is broadcast in real time at cinemas around the world, there is a gap in the current terminology. ’Mediatised live’ is a new expression, established in this thesis, to name the media form which has revolutionised the way of experiencing live theatre by broadcasting theatre live to venues around the world. By asking the question ‘Is the need for liveness dying?’ this thesis invest

Abstract While outcome studies in pediatric obesity have received considerable attention, research on different components of effective interventions remains limited. Little is known which psychological method (i.e., behavior modification, cognitive behavior therapy and family therapy) is most useful or how the choice of program delivery (group/individual) influences the intervention outcomes. Gro