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Största delen av det svenska vägnätet består idag av belagd väg. Med det i åtanke så krävs det därför att vägarna vid sin anläggning respektive när underhållsåtgärd sker blivit väl dimensionerade samt blivit korrekt utförda. Under en tid i Sverige har Trafikverket med sitt dokument TRVK väg numera TRVINFRA styrt hur de statliga vägarna skall dimensioneras med sina tre dimensioneringsklasser. I dirThe largest part of the Swedish state roads are today paved. With this in mind it is therefore demanded when a road in question is constructed respectively when a maintenance measure is taken place that the dimensioning of the road from the start was done properly. Since a while back in Sweden it has been upon the Swedish Transport Administration to regulate with their document “TRVK Väg”, now TRV

Introduction: Cytostatic pharmaceuticals are increasingly detected in the aquatic environment, raising concerns due to their persistence and toxicity. Background: Conventional wastewater treatment processes do not effectively remove these compounds. Advanced oxidation processes, such as ozonation, are needed to degrade cytostatic pharmaceuticals during wastewater treatment. However, these process

BACKGROUND/OBJECTIVES: Iron deficiency has been suggested as a potential mechanism for attention-deficit hyperactivity disorder (ADHD) development due to involvement in neurotransmitter synthesis and transporter expression. As iron deficiency is particularly common in women of reproductive age, often due to heavy menstrual bleeding (HMB), we aimed to explore the relationship between iron deficienc

Studier visar på att ljudnivån på en intensivvårdsavdelning är hög. I många studier har man kommit fram till att en stor del av ljudet orsakas av samtal mellan personal. Samtal svarar för 26% av allt ljud på en intensivvårdsavdelning. Sömn är en grundläggande komponent för att återställa energi och fysisk hälsa efter sjukdom. Upp till 58 % av alla patienter som sover vaknar på grund av oljud inne

Introduction: The objective of the study was to investigate the impact of newer biologic treatments including rituximab, abatacept and tocilizumab on antibody response following pneumococcal vaccination using a 7-valent conjugate vaccine in patients with established rheumatoid arthritis (RA). Methods: Patients with RA receiving rituximab, abatacept or tocilizumab as monotherapy or combined with me

The diatom Pseudo-nitzschia multistriata exhibits a diplontic life cycle composed of an extensive phase of vegetative cell division and a brief phase of sexual reproduction. To explore genotypic stability, we genotyped seven polymorphic microsatellite loci in 26 monoclonal strains over 3-16 months in a culture maintenance regime. Moreover, to assess inheritance patterns of the microsatellite allel

In the boundary of materials and colloidal science, TEM became a very powerful technique used to image the interfaces and early stages of mesoporous materials formation, to obtain symmetry information about the porous network at the meso-scale, furthermore to obtain images of final structures and transformations that could not be observed otherwise. The aim of the present contribution is to give i

The combined effect of feeding regime and photoperiod on the growth of juvenile Atlantic cod Gadus morhua in land-based recirculating aquaculture systems (RAS) was examined using three different commercial diets. Fish of 8-10 g were reared in 1 m³ tanks at an initial density of 10 kg m-³ for 78 d. Three RAS units were used to simultaneously test three feed/photoperiod regimes that might be encount

We report on room-temperature electrical measurements of multibranch junction (MBJ) devices made from a semiconductor heterostructure. We show that the MBJ devices exhibit an interesting electrical property. If the voltage output at one branch is measured as a function of the voltages inputs to all the other branches, the output voltage is determined predominately by the most negative, or the lowe

Apolipoprotein M (apoM) is a 188 amino acid, 25 kDa protein belonging to the lipocalin protein superfamily. Although predominantly associated with high density lipoprotein, apoM is found in all major lipoprotein classes. To facilitate clinical studies of apoM, we have developed a sandwich ELISA for the measurement of apoM in human plasma. This method has been used to investigate normal apoM variat

We report on a large scale calculation concerning the 5s(2) S-1 and 5s5p P-1,P-3 levels in Sr-88 I, using multiconfiguration Dirac-Fock methods. Our focus is on the P-3(2) meta-stable level, which has been shown to be extremely useful in atom cooling and trapping experiments. The lifetime for this level from our work (1071 s) agrees very well with a previous theoretical value, but not with the ava

Limonene, one of the most often used fragrance terpenes in any kind of scented products, is prone to air-oxidation. The oxidation products formed have a considerable sensitizing potential. In previous patch test studies on consecutively tested dermatitis patients, oxidized R-limonene has been proven to be a good and frequent indicator of fragrance-related contact allergy. The current study extends

A high diet quality index based on Swedish nutrition recommendations has previously been associated with reduced risk of cardiovascular disease and mortality in the Malmö Diet and Cancer (MDC) cohort. The aim of the present study was to investigate whether this diet quality index was associated with the risk for type 2 diabetes. Of 26,868 participants (44-74 years) in the MDC cohort study, 3838 ty

Several genetic studies have demonstrated an association between mutations in glucocerebrosidase (GBA), originally implicated in Gaucher's disease, and an increased risk of Parkinson's disease (PD). We have investigated the possible involvement of genetic GBA variations in PD in the Swedish population. Three GBA variants, E326K, N370S, and L444P were screened in the largest Swedish Parkinson cohor

OBJECTIVE:: HIV-2 represents an attenuated form of HIV, where many infected individuals remain “aviremic” without antiretroviral therapy (ART). However, aviremic HIV-2 disease progression exits, and in the current study we therefore aimed to examine if specific pathological characteristics of CD4+ T cells are linked to such outcome. DESIGN:: HIV-seronegative (n=25), HIV-1 (n?=?33), HIV-2 (n?=?39,

For elderly patients with mantle cell lymphoma (MCL), there is no defined standard therapy. In this multicenter open-label phase I/II trial we evaluated the addition of lenalidomide (LEN) to rituximab-bendamustine (R-B) as first-line treatment to elderly MCL patients. Patients >65 years with untreated MCL, stage II-IV were eligible for inclusion. Primary endpoints were maximally tolerable dose (MT

This study reports the prevalence and prognostic impact of right bundle branch block (RBBB) and left bundle branch block (LBBB) in the admission electrocardiogram (ECG) of comatose survivors of out-of-hospital cardiac arrest (OHCA). The present study is part of the predefined electrocardiographic substudy of the prospective randomized target temperature management trial, which found no benefit of