Filetype
Background: Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little is known about their joint effects. The aim of this study was to develop a healthy lifestyle index (HLI) composed of five potentially modifiable lifestyle factors healthy weight, physical activity, non-smoking, limited
Eighteen healthy sedentary males took part in supervised bicycle training for 50 minutes three to five times a week. Twelve subjects (group A) trained for 6 weeks at heavy intensity, and six subjects (group B) trained for 12 weeks at moderate intensity. Maximal oxygen uptake increased by about 20% (P less than 0.01). Body weight and composition as well as diet remained unchanged. After 6 weeks pla
Unsaturated solute transport is highly variable and therefore difficult to predict. In semi-arid areas, where water resources are limited, the presence of macropores is of great importance for crop production. The bromide ion (Br-) and dye tracers are useful for studies of water movement. One approach to describe the heterogeneous solute transport is to apply the concept of fractals to a dataset.
Human embryonic skin fibroblasts were pretreated with transforming growth factor-beta (TGF-beta) for 6 h and then labeled with [35S]sulphate and [3H]leucine for 24 h. Radiolabeled proteoglycans from the culture medium and the cell layer were isolated and separated by isopycnic density-gradient centrifugation, followed by gel, ion-exchange and hydrophobic-interaction chromatography. The major prote
Popular Abstract in Swedish Kemisk vittring har en avgörande betydelse för hur näringsämnen frigörs, ansamlas och kan utnyttjas i mark/växtsystemet. Vittringshastigheten har därför stor betydelse för hur skogs- och jordbrukare kan optimera skogsskötseln och skördeuttaget, inom ramen för ett uthålligt skogsbruk. I avhandlingen studeras vittring av epidot och lermineral för att vidareutveckla den geChemical weathering is one of the most important processes supporting life on Earth. Chemical weathering continuously contributes macronutrients and micronutrients to the soil solution. These recycling, essential elements are used as building blocks for all organic living matter. Chemical weathering is a vital factor in the analysis and understanding of a large number of important environmental is
Popular Abstract in Swedish Spel och spelbräden har fått lite uppmärksamhet av forskare som undersöker de antika kulturerna. Denna avhandling samlar och analyserar arkeologiskt spelmaterial från bronsålderns Kreta, definierar forskningsfältet och presenterar ett ramverk med materialavgränsningar och typologier. Vidare undersöks spelandet som en del av socialhistorien. Varje del i avhandlingen - soThe old, world-wide phenomenon of playing board games has received little attention among scholars studying the ancient cultures. This thesis collects and analyses game-related material from Bronze Age Crete, defines the field of research and provides a framework with definitions and typologies. A further goal is to use the results of the analyses to extend beyond the archaeological material and e
Popular Abstract in Swedish Hormonerna vasopressin och oxytocin frisätts från hypofysens baklob. Hypofysen är en körtel, som är belägen på undersidan av hjärnan och utsöndrar en rad olika hormoner vilka i sin tur påverkar och reglerar aktiviteten i en mängd andra organ. Vasopressin medverkar till regleringen av vatten- och saltbalansen i kroppen, men verkar också sammandragande på icke-viljestyrdVasopressin and oxytocin seem to have pivotal roles in the pathophysiology of primary dysmenorrhoea and preterm labour. Prostaglandins are also involved in the regulation of uterine activity with different receptors mediating both stimulation and relaxation. We explored different aspects of synthesis, release and receptor pharmacology of vasopressin and oxytocin. We also tested a vasopressin and o
Established histopathological criteria divide invasive breast carcinomas into defined groups. Ductal of no specific type and lobular are the two major subtypes accounting for around 75 and 15% of all cases, respectively. The remaining 10% include rarer types such as tubular, cribriform, mucinous, papillary, medullary, metaplastic, and apocrine breast carcinomas. Molecular profiling technologies, o
AIMS: To determine the basal pharmacokinetics, lung uptake and plasma cortisol suppression for two commonly prescribed inhaled corticosteroids. METHODS: Twenty-one subjects (13 healthy and 8 mild asthmatic patients) received fluticasone propionate via a chlorofluorocarbon-propelled pressurized metered-dose inhaler (pMDI) (healthy subjects only) and Diskus and budesonide via Turbuhaler, 1000 microg
Popular Abstract in Swedish I denna avhandling har morfologin och kristallstrukturen av epitaxiellt växta nanotrådstrukturer undersökts med hjälp av svepelektronmikroskopi (SEM), transmissionselektronmikroskopi (TEM) och multi-slice (MS) simuleringar. Bland annat har vi funnit att de lamellära tvillingar som ofta observeras i III-V nanotrådar växta i <111>B riktningarna tenderar att begränsas av eIn this work, the morphology and crystal structure of epitaxial semiconductor nanowire structures grown by metal-organic vapour phase epitaxy (MOVPE) are studied by electron microscopy methods. In particular, the three-dimensional structure of nanowires and nanotrees has been characterised by scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM) and multi-sli
Popular Abstract in Swedish Det finns över 500 kräftarter i världen och vi hittar dem på alla kontinenter utom Antarktis och Arktis. I Sverige finns två arter, den inhemska flodkräftan och den introducerade signalkräftan. Signalkräftan introducerades till stor del för att ersätta förlusten av flodkräfta i många pestdrabbade vatten i södra Sverige. Att det just blev signalkräftan berodde främst på In this thesis I examine the dynamics of crayfish in streams and lakes. I have studied the influence of abiotic and biotic factors on abundance, growth, trophic position, niche breadth, and recruitment of crayfish, by conducting field studies, an outdoor channel experiment and timeseries analysis. Overall, the results show that abundance of crayfish is mostly affected by the abundance of predatory
Solar electricity is one of the most promising technologies for our future electricity supply. By using concentrators, it is possible to reduce the cost of generating photovoltaic electricity. This thesis discusses how to design stationary low concentrating systems for photovoltaic or PV/Thermal applications. The first chapters briefly explain the optics of solar energy concentrators. The theoreti
In 2014, more than 200,000 refugees and migrants fled for safety across the Mediterranean Sea. Crammed into overcrowded, unsafe boats, thousands drowned, prompting the Pope to warn that the sea was becoming a mass graveyard. The early months of 2015 saw no respite. In April alone more than 1,300 people drowned. This led to a large public outcry to increase rescue operations. Throughout this period
Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska (Comprehensive summary in Swedish) Uppföljning av blodtryck (BT), medicinering och njurfunktion efter endovaskulär behandling av njurartärsteno's Bakgrund Förträngning av njuren's tillförande blodkärl, njurartärsteno's (RAS), är den vanligaste sekundära formen av högt BT (hypertension) och svarar för ca 1-5% av hypertensiRenal artery stenosis (RAS) causes hypertension, decreased glomerular filteration rate (GFR), and renal ischemia. RAS is progressive and causes 5-16% of all cases of renal failure. Prevalence of RAS in patients with hypertension is 1-5%. Today percutaneous transluminal renal angioplasty (PTRA) with or without stenting is a widely accepted treatment of RAS. Treatment of renal artery occlusion (RAO)
If we are being-of-the-world, how can we ever avoid participation? From this question Avhandling / Av_handling (Dissertation / Through_ action) unfolds. It invites to engage in an ongoing continuum of entanglements, where the moment of connection is unavoidable. This invitation demands that we are attentive to our mutual co-constitutiveness, that we take responsibility for what gets excluded as we
Background: Presence of circulating tumor cells (CTCs) is a validated prognostic marker in metastatic breast cancer. Additional prognostic information may be obtained by morphologic characterization of CTCs. We explored whether apoptotic CTCs, CTC clusters and leukocytes attached to CTCs are associated with breast cancer subtype and prognosis at base-line (BL) and in follow-up (FU) blood samples i
Background: The repertoire of measures of walking in Rett syndrome is limited. This study aimed to determine measurement properties of a modified two-minute walk test (2MWT) and a modified Rett syndrome-specific functional mobility scale (FMS-RS) in Rett syndrome. Methods: Forty-two girls and women with Rett syndrome (median 18.4 years, range 2.4–60.9 years) were assessed for clinical severity, gr
Background: Lifestyle factors may influence the risk of developing pancreatic cancer. Whereas cigarette smoking is an established risk factor, the effects of high alcohol intake and obesity are more uncertain. The aim of the present study was to examine the associations of pre-diagnostic anthropometry, alcohol consumption, and smoking habits with pancreatic cancer risk in a Swedish prospective, po
HIV/AIDS stigmatizing behaviors are a huge barrier to early detection and treatment of individuals with the AIDS virus. HIV/AIDS stigma and related consequences are debilitating, especially for vulnerable populations. This study sought to assess whether young women's HIV/AIDS knowledge levels and exposure to mass media (television and radio) have an influence on their stigmatizing behaviors and ro
The prognostic importance of tumor-specific nuclear insulin receptor (InsR) expression in breast cancer is unclear, while membrane and cytoplasmic localization of InsR is better characterized. The insulin signaling network is influenced by obesity and may interact with the estrogen receptor a (ERα) signaling. The purpose was to investigate the interplay between nuclear InsR, ER, body mass index (B
