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Preeclampsia (PE) complicates 3-8% of all pregnancies and manifests clinically as hypertension and proteinuria in the second half of gestation. The pathogenesis of PE is not fully understood but recent studies have described the involvement of cell-free fetal hemoglobin (HbF). Hypothesizing that PE is associated with prolonged hemolysis we have studied the response of the cell-free Hb- and heme de

Understanding species’ historical ranges can provide important information for conservation planning in the face of environmental change. Cromsigt et al. (this issue) comment on our recent European bison (Bison bonasus) range reconstruction, suggesting that bison were already 8000 years ago a refugee species (i.e. restricted to marginal habitat due to past human pressure) and that species distribu

Background: Epidemiologic studies of associations between folate intake and breast cancer are inconclusive, but folate and other plant food nutrients appear protective in women at elevated risk. Objective: The objective was to examine the association between folate intake and the incidence of postmenopausal breast cancer. Design: This prospective study included all women aged >= 50 y (n = 11699) f

Popular Abstract in Swedish Spel om pengar har blivit ett utbrett fenomen i Sverige under 1990-talet, med spelbutiker, spelhörnor i varuhusen, spelmaskiner och spel med kort och på roulette på pubar, pizzerior och restauranger, samt spel på Bingo-Lotto hemma i vardagsrummet. Förutom den ökade tillgången till legala spelformer blir det allt vanligare med spel i miljöer och sammanhang där det inte fGambling has become widely accepted in Sweden during the 1990s, with betting shops, gambling machines and casino-like gambling in pubs and restaurants, as well as Bingo-Lotto in our living rooms. Beyond the expansion in availability of legal gambling opportunities, the most notable change is the shift from gambling in specific venues to gambling in a much wider range of social settings. The conseq

OBJECTIVE: To present our results of non-surgical primary management of appendiceal abscesses using ultrasonic percutaneous drainage under local anaesthesia, and selective interval appendicectomy. DESIGN: Retrospective study. SETTING: University hospital, Sweden. SUBJECTS: 24 patients with appendiceal abscesses 3-12 cm in size. INTERVENTIONS: Primary ultrasonic percutaneous drainage under local an

Enzyme replacement is a potential therapy for mucopolysaccharidosis I (MPS I), a lysosomal storage disorder caused by alpha-L-iduronidase deficiency. Previous work showed improvement in the tissues of MPS I dogs treated intravenously for 3 months with recombinant human alpha-L-iduronidase (25,000 units or approximately 0.1 mg/kg/week). We have now treated an MPS I-affected dog for 13 months to ass

Aims To investigate the causal role of high-density lipoprotein cholesterol (HDL-C) and triglycerides in coronary heart disease (CHD) using multiple instrumental variables for Mendelian randomization. Methods and results We developed weighted allele scores based on single nucleotide polymorphisms (SNPs) with established associations with HDL-C, triglycerides, and low-density lipoprotein cholestero

Acidogenic fermentation of wastewater can serve as a first step in a process for mixed culture production of polyhydroxyalkanoates (PHA) since the produced volatile fatty acids (VFA) are preferred substrates for PHA production. Acidogenic fermentation of industrial wastewaters (cheese whey permeate and three pulp and paper mill effluents) was evaluated in batch and continuous experiments. From the

Popular Abstract in Swedish Summary in Swedish Populärvetenskaplig sammanfattning Förhöjt blodtryck, s.k. hypertension, är en folksjukdom i västvärlden och en riskfaktor för hjärtkärlsjukdomar som hjärtinfarkt och stroke (slaganfall). Ca 27 % av den vuxna befolkningen i Sverige beräknas ha hypertension och är lika fördelad mellan män och kvinnor. Salt beräknas bidra till förhöjt blodtryck och kan Abstract The average amount of salt ingested is about 10 grams daily compared to less than one gram in pre-historic life. Salt, althought somewhat debated, is considered a risk factor for elevated blood pressure and end organ damage beyond the blood pressure effect. Thus, salt contributes to the hypertensive phenotype, increase risk of cardiovasvcular disease, deaths and is a great socioeconomic

Waste incineration bottom ash fine fraction contains a significant amount of aluminium, but previous works have shown that current recovery options based on standard on-step Eddy Current Separation (ECS) have limited efficiency. In this paper, we evaluated the improvement in the efficiency of ECS by using an additional step of crushing and sieving. The efficiency of metallic Al recovery was quanti

We synthesized twisted bilayer graphene on single crystalline Ni(111) thin films to analyze the statistical twist angle distribution on a large scale. The twisted bilayer graphene was formed by combining two growth methods, namely the catalytic surface reaction of hydrocarbons and carbon segregation from Ni. Low energy electron diffraction (LEED) investigations directly revealed dominant twist ang

The ALICE experiment at the LHC has studied inclusive J/psi production at central and forward rapidities in pp collisions at root s = 7 TeV. In this Letter, we report on the first results obtained detecting the J/psi through the dilepton decay into e(+)e(-) and mu(+)mu(-) pairs in the rapidity ranges vertical bar y vertical bar < 0.9 and 2.5 < y < 4, respectively, and with acceptance down to zero

Assays detecting antigen (Ag)-specific T-cell responses in immune-mediated processes are increasingly employed to understand disease pathogenesis and "immune staging". The quantity and quality of starting peripheral blood mononuclear cell (PBMC) preparations are important factors in the performance of such assays. We therefore compared final PBMC yield and function by modifying parameters at the b

With aging, the incidence of falls and fractures increases. There has during the last decades been secular changes in demographics so that the proportion of elderly increases in society. Hence, there is an increasing need for clinicians to be able to make a solid appraisal of the elderly patient's functional capacity, as to identify individuals with an increased risk to fall. If high risk individu

Soil extracts are routinely used to quantify dissolved organic nutrient concentrations in soil. Here we studied the loss and transformation of low molecular weight (LMW) components of DOC (C-14-glucose, 1 and 100 mu M) and DON (C-14-amino acid mixture, 1 and 100 mu M) during extraction of soil (0-6 h) with either distilled water or 0.5 M K2SO4. The extractions were performed at 20 degrees C, at 4

Bees are mostly active during the daytime, but nocturnality has been reported in some bee families. We studied temporal flight activity in three species of carpenter bees (genus Xylocopa) in relation to light intensities. X. leucothorax is diurnal, X. tenuiscapa is largely diurnal being only occasionally crepuscular, while X. tranquebarica is truly nocturnal. Occasional forays into dim light by X.

The Swedish Arctic Ocean-96 expedition arranged by the Swedish Polar Research Committee took place during 1996 with the Swedish icebreaker M/S Oden. The expedition focused on studying the distribution of radionuclides in different water masses in the central Arctic Ocean. The expedition crossed the Barents Sea, entered the Nansen Basin at the St. Anna Trough, and continued north across the Amundse

Aim To investigate health care improvement team coaching activities from the perspectives of coachees, coaches and unit leaders in two national improvement collaboratives. Background Despite numerous methods to improve health care, inconsistencies in success have been attributed to factors that include unengaged staff, absence of supportive improvement resources and organisational inertia. Metho

Popular Abstract in Swedish Hemofili A är en form av blödarsjuka som beror på en medfödd defekt av äggviteämnet faktor VIII (FVIII). FVIII spelar en viktig roll för att kroppens blodlevringsförmåga (s.k. koagulation) ska fungera optimalt och med nedsatt funktion hos FVIII riskerar man att drabbas av allvarliga blödningar i framför allt leder, men även i muskler, slemhinnor (t.ex. näsblödning) och Haemophilia A (HA) is caused by defective synthesis of coagulation factor VIII(FVIII), which has serious effects on haemostasis; joints being the most common site of bleeding. The development of FVIII replacements has improved the situation for patients with haemophilia such that chronic arthropathy can be prevented, and life expectancy and the quality of life have increased. However, approximatel

This paper investigates the impact of scientific relatedness on knowledge dynamics in biotech at the city level during the period 1989-2008. We assess the extent to which the emergence of new research topics and the disappearance of existing topics in cities are dependent on their degree of scientific relatedness with existing topics in those cities. We make use of the rise and fall of title words