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Microbial resilience to drying-rewetting is partly driven by selection for quick colonizers

Rewetting dry soil induces enormous changes in microbial growth and biogeochemistry. Upon drying-rewetting (D/RW), bacteria have been shown to exhibit two different responses: (1) a more resilient response where bacteria start growing immediately with a quick recovery after rewetting and (2) a less resilient response where there is a pronounced lag-period before bacterial growth starts to increase

Learning blossoms : Caregiver-infant interactions in an outdoor garden setting

Plants provide unique opportunities for learning by engaging all human senses. Recent laboratory studies have shown that infants use a combination of behavioural avoidance and social learning strategies to safely learn about plant properties from adults. Here we investigate how infants and their caregivers interact with plants in an outdoor garden as a first step towards examining the operation of

Experimental and modeling study of NO formation in methyl acetate + air flames

Premixed laminar flat non-stretched flames of methyl acetate + air have been studied at atmospheric pressure. The heat flux method was employed to stabilize the flames over equivalence ratios ɸ = 0.7–1.5 at initial gas temperatures from 298 to 348 K. The laminar burning velocities of methyl acetate + air mixtures have been measured at these conditions and compared with the literature data. Laser-i

Differences in accumulation of polycyclic aromatic compounds (PACs) among eleven broadleaved and conifer tree species

PACs (polycylic aromatic compounds) are air pollutants formed in incomplete combustion, e.g., in vehicle engines. Vegetation can potentially remove substantial amounts and act as bioindicators of these pollutants. Increased knowledge of the pollutant removal efficiencies of different tree species is essential for understanding the potential benefits trees can provide urban residents. We investigat

Incidence of Kidney Replacement Therapy and Subsequent Outcomes Among Patients With Systemic Lupus Erythematosus : Findings From the ERA Registry

Rationale & Objective: There is a dearth of data characterizing patients receiving kidney replacement therapy (KRT) for kidney failure due to systemic lupus erythematosus (SLE) and their clinical outcomes. The aim of this study was to describe trends in incidence and prevalence of KRT among these patients as well as to compare their outcomes versus those of patients treated with KRT for diseas

Conversion to Arthroplasty After Internal Fixation of Nondisplaced Femoral Neck Fractures : Results from a Swedish Register Cohort of 5,428 Individuals 60 Years of Age or Older

Nondisplaced or minimally displaced femoral neck fractures are commonly treated with internal fixation, because of its less invasive and less time-consuming nature, as well its retention of the biological properties of the hip. Internal fixation with screws or pins is the current clinical routine in Sweden. However, the authors of some recent studies in elderly patients have suggested that the use

Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling

The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to

Leptin levels are associated with multiple sclerosis risk

Background: Obesity early in life has been linked to increased risk of developing multiple sclerosis (MS). Leptin and insulin are both associated with obesity, making them suitable candidates for investigating this connection. Objective: To determine if leptin and insulin are risk factors for relapsing–remitting multiple sclerosis (RRMS). Methods: In this nested case–control study using blood samp

Global catchment modelling usingWorld-Wide HYPE (WWH), open data, and stepwise parameter estimation

Recent advancements in catchment hydrology (such as understanding catchment similarity, accessing new data sources, and refining methods for parameter constraints) make it possible to apply catchment models for ungauged basins over large domains. Here we present a cutting-edge case study applying catchment-modelling techniques with evaluation against river flow at the global scale for the first ti

Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal

Volatile compounds emitted by bacteria are often sensed by other organisms as odours, but their ecological roles are poorly understood1,2. Well-known examples are the soil-smelling terpenoids geosmin and 2-methylisoborneol (2-MIB)3,4, which humans and various animals sense at extremely low concentrations5,6. The conservation of geosmin biosynthesis genes among virtually all species of Streptomyces

Spectral analysis of time domain induced polarization waveforms

Spectral induced polarization is a well-established geophysical method that can be measured in both time- and frequency domain. Time- and frequency domain methods are theoretically equivalent via the Fourier transform. However, data acquisition parameters such as the sampling frequency and pulse length affect the actual spectral content of real time domain waveforms. Comparative studies showing th

Prime-boost vaccination strategy enhances immunogenicity compared to single pneumococcal conjugate vaccination in patients receiving conventional DMARDs, to some extent in abatacept but not in rituximab-treated patients

OBJECTIVE: To explore whether a prime-boost vaccination strategy, i.e., a dose of pneumococcal conjugate vaccine (PCV) and a dose of 23-valent polysaccharide vaccine (PPV23), enhances antibody response compared to single PCV dose in patients with inflammatory rheumatic diseases treated with different immunosuppressive drugs and controls. METHODS: Patients receiving rituximab (n = 30), abatacept (n

Mesial temporal tau is related to worse cognitive performance and greater neocortical tau load in amyloid-β–negative cognitively normal individuals

We examined whether mesial temporal (Me) tau relates to cognitive performance in 47 amyloid-β (Aβ)-negative, cognitively normal older adults (>60 years old). Me-tau was measured using [18F]flortaucipir–positron emission tomography standardized uptake value ratio. The effect of continuous and categorical (stratified at standardized uptake value ratio = 1.2 [21% Me-positive]) Me-tau on cognition (mi

Clinical relevance of positive patch test reactions to lanolin : A ROAT study

Background: Lanolin is often included when patch testing for common contact allergens. The clinical relevance of a positive patch test reaction to lanolin markers is, however, still a subject for debate. Objectives: To evaluate Amerchol L101 as a marker of lanolin allergy and investigate the clinical impact of lanolin-containing moisturizers on healthy and damaged skin using the repeated open appl

Individual and Contextual Factors Associated With Hazardous Drinking in Spain : Evidence From a National Population-Based Study

BACKGROUND: Heavy drinking (HD) and binge drinking (BD) exhibit marked differences in their relationships with contextual-level factors imbedded in geographical areas of residence. The objective is to identify sociodemographic factors, both at the individual and at the contextual level, associated with these 2 main hazardous consumption patterns.METHODS: Cross-sectional study using data from the 2

Cardiac Resynchronization Therapy Guided by Echocardiography, MRI, and CT Imaging : A Randomized Controlled Study

Objectives: This study evaluated if selecting the left ventricular (LV) target segment by echocardiography-derived late mechanical activation, with access to multimodality imaging for scar and venous anatomy, could help to increase responder rates to cardiac resynchronization therapy (CRT). Background: LV lead placement is important for clinical outcome, but the optimal strategy for LV lead placem

Longitudinal Changes in Kidney Function Estimated from Cystatin C and Its Association with Mortality in Elderly Women

Background/Aims: Prospective data on age-related changes in kidney function are required, especially since the current Kidney Disease Improving Global Outcomes (KDIGO) definition has been suggested to classify a large number of elderly people with CKD. Objective: This study, a complement to our previous Cr-based study in the same cohort, is aimed at evaluating cystatin C (cysC)-based changes in ki

Disturbance history can increase functional stability in the face of both repeated disturbances of the same type and novel disturbances

Climate change is expected to increase the incidences of extremes in environmental conditions. To investigate how repeated disturbances affect microbial ecosystem resistance, natural lake bacterioplankton communities were subjected to repeated temperature disturbances of two intensities (25 °C and 35 °C), and subsequently to an acidification event. We measured functional parameters (bacterial prod

“Nobody cares about you as a group of people” : a mixed methods study of women living in congregate social housing in Ontario, Canada

Guided by the social model of disability, we carried out this exploratory study to understand the health and psychosocial needs of women living in social housing in Ontario, Canada. Using a sequential, mixed-methods design, we interviewed 19 women using a 126-item quantitative interview including six standardized measures exploring indicators of psychosocial well-being. From these findings, we des