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Popular Abstract in Swedish Denna avhandling syftar till att belysa vilket professionskunnande som blivande lärare ges möjlighet att utveckla under sin högskoleförlagda utbildning och hur detta professionskunnande kan karaktäriseras. Detta belyses genom ett antal forskningsfrågor: Vilka olika undervisningspraktiker konstituerar den högskoleförlagda lärarutbildningen? På vilket sätt upprättas dessaThe starting point for this dissertation was the reform of the school system in Sweden with consequences for teachers´ work and new demands on their professional knowledge. This thesis aims to illuminate the issue of what professional knowledge student teachers are offered during their time in the university, and how this professional knowledge can be characterised. This is carried out with respec

Popular Abstract in Swedish Antikroppar är viktiga beståndsdelar av det naturliga immunförsvaret som skyddar oss mot smittämnen, såsom bakterier och virus. Utvecklingen av olika genetiska och biokemiska teknologier har dessutom möjliggjort användningen av antikroppar för en mängd ändmål, bl a för diagnostik och behandling av infektionssjukdomar och cancer. I denna avhandling, som bygger på fem vetAntibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. Despite tremendous advances in all fields

This thesis presents a study on performance analysis and optimal design of heat exchangers and heat exchanger networks. The study includes an experimental investigation of steam condensation in plate heat exchangers, optimal design of plate heat exchangers and plate-fin heat exchangers, and optimization of heat exchanger networks. In the experimental investigation of steam condensation in plate h

Aims To compare the effect of initial monotherapy with either bisoprolot or enalapril, followed by their combination, on mortality and hospitalization in patients with mild-to-moderate CHF. Methods and results One thousand and ten patients with mild-to-moderate CHF and left ventricular ejection fraction <= 35%, without ACE-inhibitor, beta-blocker, or angiotensin-receptor-blocker therapy were rando

Northern hemisphere peatlands play an important role in the global carbon (C) cycle, accounting for about 30% of global soil C and similar to 10-25% of global natural methane (CH4) emissions. Satellite remote sensing has the potential for extracting continuous information related to C exchange rates at regional and global extents, yet, few studies have focused on peatlands. In this study we examin

Background We aimed to accurately estimate the frequency of a hexanucleotide repeat expansion in C9orf72 that has been associated with a large proportion of cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Methods We screened 4448 patients diagnosed with ALS (El Escorial criteria) and 1425 patients with FTD (Lund-Manchester criteria) from 17 regions worldwide for the

BACKGROUND: Halothane and isoflurane have been shown to induce disparate effects on different brain structures in animals. In humans, various methods for measuring cerebral blood flow (CBF) have produced results compatible with a redistribution of CBF toward deep brain structures during isoflurane anesthesia in humans. This study was undertaken to examine the effects of halothane and isoflurance o

The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. At low concentrations of denaturant the transition state occurs early in the folding reaction, whereas at high denaturant concentration it moves close to the nati

Popular Abstract in Swedish Avhandlingen är en studie av kvinnors brevskrivning i Sverige under 1700-talet. Breven är skrivna av ett antal kvinnor från de högre samhällsskikten (adel och borgerskap) under 1780- och 1790-talen. Flertalet av breven är skrivna på svenska, men några också på franska. Huvudsyftet med avhandlingen är att undersöka relationen mellan idén om att kvinnor skrev annorlunda, This dissertation is a study of women's letter-writing in eighteenth-century Sweden. The letters are written by a number of women from the uppper classes (nobility and bourgeoisie) during the last two decades of the eighteenth century. The majority of the letters are written in Swedish, some however in French. The main aim is to examine the relationship between the idea of women as a special kind

The dissertation can be divided into two parts, the first of which is a detailed analysis of three excavations concerning Mellanbyn in southern Malmö. In the second part I study the more general development of society, relating Mellanbyn to the surrounding area as well as to the region as a whole during Late Bronze Age and the Early Iron Age. The aim can be summed up as being to study the developm

The dissolution and surface complexation of a non-stoichiometric hydroxyapatite (Ca-8.4(HPO4)(1.6)(PO4)(4.4)(OH)(0.4)), (HAP) was studied in the pH range 3.5-10.5, at 25 degrees C in 0.1 M Na(Cl). The results from well-equilibrated batch experiments, potentiometric titrations, and zeta-potential measurements were combined with information provided by Attenuated Total Reflectance Fourier Transform

Background and objectives In accordance with clinical findings, myringoscterosis develops after otitis media (OM) and paracentesis in an experimental setting. The pathogenesis of this phenomenon of calcification is poorly understood. As the calcification process and the sclerotic plaques of the drum mimics features of bone tissue, this study explores tympanic membrane calcium deposition in associa

Mice were subjected to gastrectomy (GX) or sham operation (controls). Four to six weeks later the pancreatic islets were isolated and analysed for cAMP or alternatively incubated in a Krebs-Ringer based medium in an effort to study insulin secretion and cAMP accumulation in response to glucose or the adenylate cyclase activator forskolin. Freshly isolated islets from GX mice had higher cAMP conten

The use of topographical data in hydrological and agricultural applications has increased with GPS data availability and the concept of precision agriculture. This thesis investigates the relationships between topography and in one case simulated soil moisture and in the other case yield. The yield was recorded with a new optical sensor, which uses a digital camera to detect objects and records th

Streptococcus pyogenes is a common human pathogen causing mild infections such as tonsillitis and pharyngitis, but is also the cause of life-threatening conditions. To be able to infect the human host, S. pyogenes express different virulence factors. The surface-expressed M protein is a major virulence factor of S. pyogenes, mediating resistance to killing by human neutrophils. Results presented i

Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction are believed to be at high risk for progression to mild cognitive impairment due to Alzheimer's disease (AD). Clinical trials in later stages of AD typically include a coprimary endpoint to demonstrate efficacy on both cognitive and functional assessments. Recent trials focus on cognitively-normal

Background: Age, gender and socioeconomic status have been shown to be associated with the use of prescription drugs, even after adjustment for multimorbidity. General practitioners have a holistic and patient-centred perspective and our hypothesis is that this may reflect on the prescription of drugs. In Sweden the patient may seek secondary care without a letter of referral and the liability of

The timing of the ice margin retreat of the Late Glacial Patagonian Ice Sheet (PIS) in southern Patagonia has been the object of discussion for many years. In order to resolve questions about the complex response of the PIS to past climate change, any geological interpretation and data modelling need evaluation against an absolute chronology. The aim of this project is to investigate the applicabi

Popular Abstract in Swedish Hur kommer det sig att liknande reformprogram återfinns i olika länder? Varför väljs vissa idéer framför andra? Avhandlingen syftar till att öka förståelsen av så kallad policydiffusion, spridning av olika typer av policy, och den dynamik som omgärdar spridningen. Detta görs genom att undersöka hur externa, eller utländska, idéer integreras och översätts i en ny omgivniSimilar policies may be found in different countries. This, in turn, is an indication that policies travel. But why are certain policies imitated while others are not? The author seeks to further our understanding of policy diffusion and its dynamics by investigating how foreign ideas are integrated and translated into new contexts, and how these imported ideas influence national policymaking and

A large and rapidly growing population in Kenya together with increasing demands put heavy pressure on the country’s resources. Primary to produce enough food but also to meet other needs such as access to timber and firewood. A large part of the population relies on yields from their own farming for their survival. The farms are generally small and the needs many which makes it important to get o