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BACKGROUND: Preterm birth remains the major risk factor for the development of intraventricular hemorrhage, an injury that occurs in 25% of very low birth weight infants. Intraventricular hemorrhage is thought to be venous in origin and intrinsic thromboses in the germinal matrix are likely to play a triggering role. Antithrombin, a glycoprotein synthesized in the liver, is the major plasma inhibi

Healthy eye lenses are transparent and flexible, able to adapt shape in order to focus on far away and close-by objects. With age, however, this flexibility is lost, leading to a condition known as presbyopia. This vision disorder where close-by objects appear blurred commonly starts around the age of 40. The aim of this thesis is to elucidate the molecular origin of the gradual hardening of the c

Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The most widespread underlying genetic deficiency is a heterozygous deficiency of the serine protease inhibitor Cl esterase inhibitor (C1-Inh). In addition to low C4 levels, the most important laboratory parameter for correct diagnosis of HAE or angioedema du

Background: Evidence-based guidelines are needed for effective delivery of home oxygen therapy to appropriate patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD). Methods: The multidisciplinary panel created six research questions using a modified Delphi approach. A systematic review of the literature was completed, and the Grading of Recommendations Asse

This paper presents a combined experiment and identification procedure, well suited to obtain low-order dynamic models of a patients’ response to continuous drug administration. The experiment requires no a priori information and is of very short duration. The identification method provides both a parametric low-order model, and an estimate of the parameter error covariance. It has been demonstrat

An electron beam of very high energy (50–250 MeV) can potentially produce a more favourable radiotherapy dose distribution compared to a state-of-the-art photon based radiotherapy technique. To produce an electron beam of sufficiently high energy to allow for a long penetration depth (several cm), very large accelerating structures are needed when using conventional radio-frequency technology, whi

BALTHAZAR BERLING - LE FAIT DU CORPS (BARTHÉLÉMY) LOUI KUHLAU - THE MUNDANE EGG In language you divide, categorize and combine. As words enters your language they create parameters in a spectrum, in which you previously didn’t make any distinctions. As you come into being without a language, the first period of life is lived in a continuous spectrum. A world where everything is one. Your senses co

https://www.khm.lu.se/balthazar-berling-loui-kuhlau - 2026-07-15

The vascular system is vital for all tissues and the interest in its visualization spans many fields. A number of different plant-derived lectins are used for detection of vasculature; however, studies performing direct comparison of the labeling efficacy of different lectins and techniques are lacking. In this study, we compared the labeling efficacy of three lectins: Griffonia simplicifolia isol

Genetic variations are investigated in human and many other organisms for many purposes (e.g., to aid in clinical diagnosis). Interpretation of the identified variations can be challenging. Although some dedicated prediction methods have been developed and some tools for human variants can also be used for other organisms, the performance and species range have been limited. We developed a novel v

Purpose: Adolescent and young adult (AYA) cancer survivors have unique psychological needs and require tailored support, as they transition from hospital settings following cancer treatment. This study aimed to evaluate the safety and clinical effectiveness of the online "Recapture Life" program to improve AYA aged survivors' psychological adjustment in early cancer survivorship. Methods: The inte

Project Psyche is a transnational initiative to generate and study chromosome-level reference genomes of all ~11 000 species of Lepidoptera (butterflies and moths) found in Europe. Here, we describe the decentralised network of collection and sequencing hubs that has enabled rapid progress, the standardised protocols for sampling and sequencing, and the collaborative framework for data analysis. W

We present a method for the classification of all weak travelling-wave solutions for some dispersive nonlinear wave equations. When applied to the Camassa-Holm or the Degasperis-Procesi equation, the approach shows the existence of not only smooth, peaked and cusped travelling-wave solutions, but also more exotic solutions with fractal-like wave profiles.

The demographic shift is fast becoming a global challenge and an important public health concern. The proportion of people over 65 years is currently 10% around the world, but it is expected to rise to 22% by the year 2050 [1]. Populations ageing rapidly is widely seen as one of the most powerful transformative forces affecting society over the next four decades [1–4]. The ageing population is pro

Background: Due to the demographic challenge in most countries it is important to consider making work life sustainable. A sustainable work life is of importance in all age groups when working life will be extended to a higher age. Aim: Towards a theoretical model with an impact on a sustainable working life for all ages, the swAge - model. Method: The theoretical model, the swAge-model, is develo