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Vårterminen 2024
Här hittar du som är student eller medarbetare hos oss information om valbara kurser, kalendarium för hela terminen. JanuaryWeek 3: 15-21 January15.1 Official start of spring semester15.1 MFAAR meeting 10.00-11.0015.1 Meeting with the exchange students 11.00-11.3015.1 ALL STUDENTS 12.00-13.00 Student forum with lunch WELCOME TO NEW SEMESTER 19.1 Application portal BFA and MFA prog
https://www.khm.lu.se/varterminen-2024 - 2026-05-23
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Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin
Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel
Expanding the Discourse on Sustainability: Existential Sustainability
In recent years, society has seen a growing need to broaden the conversation around sustainability beyond its traditional pillars of social, environmental, and economic concerns. There's a call to include the existential dimensions of human life. In autumn 2023, the Agenda 2030 Graduate School offered a doctoral course on Existential Sustainability. The course concluded with a student conference f
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Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures
Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We
Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities
In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha
Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis
To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc
Purification of streptococcal protein G expressed by Escherichia coli by high performance liquid affinity chromatography using immobilized immunoglobulin G and albumin
A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz
Antibody-dependent allostery of the M1 protein
Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
Flower Power!
Välkommen till en fullspäckad dag där vi utforskar växternas power tillsammans! Welcome to a day where we explore the power of plants together! Program mellan kl 11-15:Växternas sinnen. Utställning i trädgården.Blossom exchange - byt, odla och dela dina växter med andra. Haka på studentorganisationen Hållbart universitet för att fira växtvärlden! Vårt växtutbyte är ett perfekt tillfälle för trädgå
https://www.botan.lu.se/flower-power - 2026-05-23
