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Background: Non-motor symptoms are present in Parkinson's disease (PD) and a key determinant of quality of life. The Non-motor Symptoms Scale (NMSS) is a validated scale that allows quantifying frequency and severity (burden) of NMS. We report a proposal for using NMSS scores to determine levels of NMS burden (NMSB) and to complete PD patient classification. Methods: This was an observational, cro
Background Chronic congestive heart failure is a complex condition that leads to dysfunction in the peripheral microcirculation. We have previously shown that vascular reactivity is reduced with increasing age. In this study, we examined a group of very old patients with severe chronic heart failure to test the hypothesis that vascular function is further compromised by a combination of heart fail
Laminar burning velocity measurements of 50:50 and 85:15% (by volume) H-2-CO mixtures with O-2-N-2 and O-2-He oxidizers were performed at lean conditions (equivalence ratio from 0.5 to 1) and elevated pressures (1 atm-9 atm). The heat flux method (HFM) is employed for determining the laminar burning velocity of the fuel-oxidizer mixtures. HFM creates a one-dimensional adiabatic stretchless flame w
Potatoes Solanum tuberosum, L are among the most consumed crop type by millions of people around the world. It has high amount of starch content and it is known to be a good source of potassium, vitamin B6, vitamin C and fiber. There are more than 4000 varieties of potatoes. Salome, Ditta and Asterix cultivars are among well-known potatoes in the Swedish market. In recent years the consumption of
Methods and equipment used for fighting forest fires are different from the ones used in urban fires. Generally, the wildfires are intense, require more resources and tend to spread rapidly. The effectiveness of different suppression techniques is difficult to evaluate since they depend on terrain, weather conditions and other varying factors over time and space. The current study focuses on the s
In November 2011, at the brink of state failure the United Nations and the Gulf Cooperation Council brokered a deal with the Yemeni government for the implementation of a democratic transition towards peace. The Yemeni people, tired of the authoritarian regime of Ali Abdullah Saleh greeted the initiative and the opportunity of finally getting to shape the Yemeni state in their favor. But even thou
Integrated product development combines multiple disciplines (mechanics, engineering, informatics) in the development of complex products in corporations. In today’s economy, the development environment could be considered volatile, uncertain, complex and ambiguous, which prompts for experimentation, incremental product design and continuous engagement with the customer or end user. Literature sug
The Covid-19 crisis presents an opportunity to evaluate the effectiveness of fiscal policy by investigating how fiscal stimuli aided recovery from the pandemic in Sweden. As Covid-19 have led to increased concerns of unsustainable debt levels, questions of how government spending has affected the economic rebound and fiscal sustainability arises. To tackle these questions, I evaluate pre-existing
The lichen family Teloschistaceae is one of the larger families of lichenized fungi. Currently it includes one very large heterogenous genus, Caloplaca, with some 1000 or more species with a vast variation in morphology, anatomy and chemistry. The rest of the family is split into 1015 smaller genera, each with 20 or fewer species. There is no modern classification of the family based on molecular
Specimens of Caloplaca belonging to the group of C. citrina (Hoffm.) Th. Fr. were collected in different localities in the provinces of Buenos Aires (Argentina) and studied using morphology and nrITS data. They were identified as C. austrocitrina Vondrak, Riha, Arup & Sochting, a species newly described from the Black Sea area, but also found in other European countries. These findings are the
The exposure to flooding in coastal Bangladesh is expected to increase throughout the century as a result of climate change-induced sea level rise and intensified monsoon precipitation. The current consequences of flooding include damage to infrastructure, economy, and health through inundation and saline intrusion, and are likely to affect a larger population in the future. Adequate flood modelli
Intellectual Property Rights, IPR, are tools to incentivize innovation and investment in Research and Development (R&D) to promote growth and are traditionally used for economic interests before environmental and social concerns. The research project IPACST has developed a business tool kit for supporting organizations in designing their IP models to increase environmental and social impact. T
Problemformulering: Byggprocessen är idag långsam, kostsam och genererar stora mängder spill och utsläpp. För att kunna möta bostadsbehovet från den snabbt växande befolkningsmängden måste tekniken utvecklas, den måste bli snabbare och mer kostnadseffektiv. Med ny teknik där betongelement tillverkas genom automatiserad och datorstyrd 3D-printning kan eventuellt hela betongbyggnadsprocessen effektiQuestion formulation: The construction process today is slow, costly and generates large amounts of waste and emissions. In order to meet housing needs of the rapidly growing population in a sustainable way, the technology must evolve; it must be faster and more cost-effective. New technology, where concrete is manufactured by automated and computer-controlled 3D-printing, can possibly streamline
This paper examines the relation between violent conflicts and democratization in Georgia. Since independence in 1991, Georgia has grown towards increased democratization but within the political transition, many obstacles, in form of violent conflicts and war have threatened the country. In the Democratization and War theory, Mansfield & Snyder argues that increased democracy increases the ri
This thesis evaluates the EU-level tobacco products regulation and the regulation of tobacco products for oral use, in particular. The evaluation includes a historical overview of the development of relevant secondary legislation and a more detailed analysis of the current regulatory state. Following the analysis of the Tobacco Products Directive as the main legal instrument in the European tobacc
It is currently unclear how often genes that are mutated to cause rare, early-onset monogenic forms of disease also harbor common variants that contribute to the more typical polygenic form of each disease. The gene for MODY3 diabetes, HNF1 alpha, lies in a region that has shown linkage to late-onset type 2 diabetes (12q24, NIDDM2), and previous association studies have suggested a weak trend towa
Softwood is an interesting raw material for the production of fuel ethanol as a result of its high content of hexoses, and it has attracted attention especially in the Northern hemisphere. However, the enzymatic hydrolysis of softwood is not sufficiently efficient for the complete conversion of cellulose to glucose. Since an improvement in the glucose yield is of great importance for the overall e
