Filetype
The sequence diversity of the entire mitochondrial control region (CR) of three meadow viper (Vipera ursinii) populations was analysed and compared to previously documented nuclear genetic variability at the major histocompatibility complex (MHC) Class I loci. One of the populations, a small and inbred Hungarian population, exhibited no MHC polymorphism, whereas the two other, sampled from large v
The role of electrostatic interactions in the assembly of a native protein structure was studied using fragment complementation. Contributions of salt, pH, or surface charges to the kinetics and equilibrium of calbindin D-9k reconstitution was measured in the presence of Ca2+ using surface plasmon resonance and isothermal titration calorimetry. Whereas surface charge substitutions primarily affect
Aims. A transient astrophysical event observed in both gravitational wave (GW) and electromagnetic (EM) channels would yield rich scientific rewards. A first program initiating EM follow-ups to possible transient GW events has been developed and exercised by the LIGO and Virgo community in association with several partners. In this paper, we describe and evaluate the methods used to promptly ident
Using kilometric arrays of air Cherenkov telescopes at short wavelengths, intensity interferometry may increase the spatial resolution achieved in optical astronomy by an order of magnitude, enabling images of rapidly rotating hot stars with structures in their circumstellar disks and winds, or mapping out patterns of nonradial pulsations across stellar surfaces. Intensity interferometry (once pio
Objective: Parental history of diabetes and specific gene variants are risk factors for type 2 diabetes, but the extent to which these factors are associated is unknown. Methods: We examined the association between parental history of diabetes and a type 2 diabetes genetic risk score (GRS) in two cohort studies from Finland (population-based PPP-Botnia study) and the US (family-based Framingham Of
The ability of in vitro-expanded neural precursor cells or cell lines to differentiate following transplantation has significant implications for current research on central nervous system repair. Recently, interest has been focussed on grafts of such neural precursors implanted also into the eye or retina. Here, we demonstrate with a non-traumatizing subretinal transplantation method, that grafts
The entity sinusitis, bronchiectasis, and situs inversus is since long named Kartagener syndrome. Nowadays the designation used is primary ciliary dyskinesia (PCD), which implies cilia with decreased or total absence of motility, which may result in sinusitis, chronic bronchitis, bronchiectasis, and male infertility. A large number of deficiencies detectable on the ultrastructural level give rise
Numerous databases containing information about DNA, RNA and protein variations are available. Gene-specific variant databases (locus specific variation databases, LSDBs) are typically curated and maintained for single genes or groups of genes for a certain disease(s). These databases are widely considered as the most reliable information source for a particular gene/protein/disease, but it should
Among the fundamental problems in canopy turbulence, particularly near the forest floor, remain the local diabatic effects and linkages between turbulent length scales and the canopy morphology. To progress on these problems, mean and higher order turbulence statistics are collected in a uniform pine forest across a wide range of atmospheric stability conditions using five 3-D anemometers in the s
It has been argued that the decay rates of several radioactive nuclides are slightly lower at Earth's aphelion than at perihelion, and that this effect might depend on heliocentric distance. It might then be expected that nuclear decay rates be considerably lower at larger distances from the sun, e.g., in the asteroid belt at 2-3 AU from where most meteorites originate. If so, ages of meteorites o
Background: The etiology of male breast cancer is poorly understood, partly due to its relative rarity. Although tobacco and alcohol exposures are known carcinogens, their association with male breast cancer risk remains ill-defined. Methods: The Male Breast Cancer Pooling Project consortium provided 2,378 cases and 51,959 controls for analysis from 10 case-control and 10 cohort studies. Individua
Experimental studies of core-excited molecules using three-dimensional multi particle momentum imaging are presented where bond rearrangement processes in dication species are analysed. The aim of the study is to understand the relation between the geometric changes associated with core-excited states and the kinetic energy released in particular molecular dissociation processes. The kinematics of
Cycling as a transport mode has gradually become more attractive in cities during the last 10 years. However, not all cities give due consideration to cycling issues in the planning process. In many transport systems, cycling and issues of vélomobility are still neglected. Recent research considers several aspects of cycling, however, few studies have shown why differences in for example modal spl
Objective: To evaluate the modification of lipid and lipoprotein by use of low doses of continuous-combined formulations of 17beta-estradiol (E-2) and norethisterone acetate (NETA) in healthy postmenopausal women. Design: The study was designed as a double-blind, randomized, placebo-controlled trial. A total of 120 healthy postmenopausal women were randomized to one of three treatment arms: (1) pl
The legacy of Nisbett and Wilson's classic article, Telling More Than We Can Know: Verbal Reports on Mental Processes (1977), is mixed. It is perhaps the most cited article in the recent history of consciousness studies, yet no empirical research program currently exists that continues the work presented in the article. To remedy this, we have introduced an experimental paradigm we call choice bli
The benefits of archaeology are seldom discussed in relation to the evident fascination of many people with the subjects of archaeology and the past. This current popularity of a certain way of perceiving archaeology and the past can be seen as a part of larger trends associated with the Experience or Dream Society as described by scholars such as Gerhard Schulze and Rolf Jensen. In this paper, I
Tropical forest soils are a significant source for N2O and NO. Current estimates of N2O and NO emissions areuncertain due to the limited number of fieldmeasurements and model input data. Furthermore, considerable spatialand temporal variability exists due to variation of soil properties, vegetation characteristics and meteorology.Weused a process-based model (ForestDNDC-tropica) to estimate N2O an
This essay is a presentation of the elegy for cities in Andalusí-Arabic poetry. In this essay, which is a presentation, the reader is presented with three full poems of Andalusi-Arabic Elegy for lost cities, brief analyses of the poems in terms of content and style, background information concerning the poems, short biographies of the poets. Different aspects of the Andalusí-Arabic elegy for citie
Singapore and Finland, despite having very different approaches to basic education, both perform highly in standardized testing and are respected internationally for their education systems. This paper takes a policy-planning view in analysing what makes these systems tick, looking specifically for similarities in these contrasting systems, or a “different process same outcome” approach. This mean
