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Background: Up to now, there are no clinically available minimally invasive biomarkers to accurately identify mild cognitive impairment (MCI) patients who are at greater risk to progress to Alzheimer’s disease (AD) dementia. The recent advent of blood-based markers opens the door for more accessible biomarkers. We aimed to identify which combinations of AD related plasma biomarkers and other easil
Kidney failure and associated uraemia have implications for the cardiovascular system, brain, and blood-brain barrier (BBB). We aim to examine BBB disruption, by assessing brain-derived neurotropic factor (BDNF), neuron-specific enolase (NSE) levels, and gut-blood barrier (GBB) disruption by trimethylamine N-oxide (TMAO), in chronic kidney disease (CKD) patients. Additionally, endothelial tight-ju
Background: While occupational therapists (OT) and physiotherapists (PT) have a central role in reablement, no structured approach for these professions has been described in Sweden. Aims/Objectives: The aim was to explore the feasibility of a reablement program developed to guide OTs and PTs in a Swedish municipality context. Material and methods: Eligible participants were OTs and PTs working wi
Background and purpose — Total knee replacement (TKR) studies usually analyze all-cause revision when con-sidering relationships with patient and prosthesis factors. We studied how these factors impact different revision diagnoses. Patients and methods — We used data from 2003 to 2019 of TKR for osteoarthritis from the arthroplasty regis-tries of Sweden, Australia, and Kaiser Permanente, USA to st
BACKGROUND: Accumulating evidence suggests a survival benefit after curative oesophageal cancer surgery in women compared with men. The aim of this study was to explore sex disparities in survival after surgery with curative intent in patients with oesophageal cancer.METHODS: This was a population-based cohort study, including all patients with oesophageal or gastric cancer who underwent surgery w
An experimental investigation has been performed where the influence of metal salts on soot formation has been studied. By combining two-dimensional laser-induced incandescence (LII) and elastic light scattering (ELS), two-dimensional information could be obtained on soot properties in the flames. For these studies, seven metal salts (NaCl, MgCl2, AlCl3, KCl, CaCl2, FeCl3 and ZnCl2) were dissolved
In the absence of other information, people put more weight on their own opinion than on the opinion of others: they are conservative. Several proximal mechanisms have been suggested to account for this finding. One of these mechanisms is that people cannot access reasons for other people’s opinions, but they can access the reasons for their own opinions—whether they are the actual reasons that le
Objective: Retinopathy of prematurity (ROP) is a multifactorial disease linked to low insulin-like growth factor (IGF)-I levels and perhaps to postnatal inflammation. Here, we investigated the longitudinal postnatal serum concentrations of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)-α in relation to IGF-I levels and ROP. Design: The study cohort included 52 infant
Katalys är ryggraden i många processer i vardagen. Även människokroppen styrs huvudsakligen av katalysatorer. Detta viktiga koncept tillåter oss att på ett miljövänligt sätt konvertera råmaterial som råolja och naturgas till värdefulla och oersättliga produkter, till exempel motorbränslen, läkemedel och agrokemikalier. En katalysprocess drivs av en katalysator, vilket således är en substans som, uNew classes of N-heterocyclic carbene-palladium(II) complexes containing either a vinyl group in different positions or an anthracene tag in the backbone of the N-heterocycle were synthesized and fully characterized. The vinyl based complexes were copolymerized with divinylbenzene to fabricate robust polymer-supported NHC-Pd(II) systems, while the anthracene based complexes were π-stacked onto the
BACKGROUND: Many lifestyle factors have been associated with the metabolic syndrome (MetS). However, most of these studies have not considered the potential impact of obesity and have often only investigated one lifestyle factor at the time. We aimed to investigate the interplay between body mass index (BMI) and MetS with respect to multiple lifestyle factors.METHODS: BMI and MetS [National Choles
Background: Diabetes is presently classified into two main forms, type 1 and type 2 diabetes, but type 2 diabetes in particular is highly heterogeneous. A refined classification could provide a powerful tool to individualise treatment regimens and identify individuals with increased risk of complications at diagnosis. Methods: We did data-driven cluster analysis (k-means and hierarchical clusterin
The influence of the ignition quality of diesel-and gasoline-like fuels on the lift-off length of the jet were investigated in an optical heavy duty engine. The engine was operated at a load of 22 bar IMEPg and 1200 rpm. A production type injector with standard holes were used. The lift-off length was recorded with high speed video Different injection pressures and inlet temperatures were used to
Bakteriesläktet Aerococcus består av åtta arter av s.k. Grampositiva kocker. Den första arten, A. viridans, beskrevs 1953 och kopplingar gjordes mellan den och en allvarlig sjukdom hos hummer. Det skulle dröja åtskilliga decennier innan nästa aerokockart, A. urinae, upptäcktes. Denna kopplades till urinvägsinfektioner (UVI) och bakteriemi, dvs. växt av bakterier i blodet, hos människa. Därefter haThe genus Aerococcus comprises eight species of Gram-positive cocci. The incidence and the clinical importance of aerococcal infections have been underestimated in the past, due to species identification difficulties. In our first study, we evaluated the usefulness of MALDI-TOF MS as a species identification method for aerococci and found that it had a high sensitivity and specificity. Two populat
Prediction of the insulating capability of building products in fire conditions would support the product development process. Stone wool insulation is a widely used material in fire barrier constructions. Due to the combustion of its organic content, the temperature inside stone wool can rise above the temperature of the exposed boundary. This temperature rise is difficult to predict. An extensiv
Objective: To examine associations between trabecular bone (TB) texture and magnetic resonance imaging (MRI)-defined osteophytes in finger joints without radiographic osteoarthritis (OA) using an augmented variance orientation transform (AVOT) method. Design: In a cross-sectional study, associations of the TB texture and osteophytes were examined in 21 women with mean (standard deviation) age of 6
Post-translational modifications (PTMs) such as nitration of Tyr (Y) residues and di-tyrosine (DT) formation are known to impact the aggregation behavior of α-synuclein (α-syn), a protein closely linked to Parkinson's disease. Using tetranitromethane (TNM) as a model nitrating agent, we systematically investigated the chemical modifications of α-syn and their consequences for aggregation. Mass spe
Heroic narrations of Waffen-SS are encountered in several memory cultures, notleast among Cold War émigrés.1 One example of this is the Ukrainian communityin Canada, in particular the so-called third wave of Displaced Persons, refugeesfrom communist rule in Eastern Europe. It constitutes a community of memoryin many key respects at odds with the Canadian mainstream society. Whereas theHolocaust ocThe 14th Waffen-SS Division Galizien was set up in 1943 by Ukrainian volunteers, largely sympathetic to the more conservative Melnyk wing of the Organization of Ukrainian Nationalists (OUN(m)). Its members took a personal oath of allegiance to Adolf Hitler and served in a number of capacities on the eastern front. In addition to combat at the front, the unit partook in the crushing of the Slovak N
The aim of this report is to investigate how and if FDS simulations performed by experienced fire protection consultants varies in result, and how different Swedish fire protection companies works with quality assurance of calculations carried out by FDS. This was examined by allowing eight fire protection consultants from different companies simulate a specific scenario with FDS 5, without prior
Objective. The volume of colonoscopies performed is increasing and differences in colonoscopy practice over time and between centres have been reported. Examination of current practice is important for benchmarking quality. The objective of this study was to examine variations in colonoscopy practice in endoscopy centres internationally. Material and methods. This observational study prospectively
