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Background: Cancer care for individuals with intellectual disabilities (ID) is challenging, with evidence of disparities, late diagnoses, and overlooked experiences of the individuals in question.Aim: To explore how individuals with concomitant ID and cancer experience the illness and navigate cancer care trajectories and everyday life from perspectives of themselves, their relatives and professio
Purpose: Glomerular filtration rate (GFR) is used to evaluate kidney function. Creatinine and cystatin C levels C are the two endogenous substances used to estimate GFR (eGFRCR and eGFRCYS). Agreement between the two is reflected by the eGFRCYS/eGFRCR-ratio, and an eGFRCYS/eGFRCR-ratio <0.70 is strongly associated with mortality and morbidity. An explanation is a selective decrease in the filtrati
Anthropogenic activities threaten many wildlife populations by increasing mortality rates, making it crucial to identify the locations and causes of mortality to inform conservation actions. Technological advancements, such as GPS satellite tracking, enable precise recording of wildlife movements. High-resolution data from such devices can facilitate rapid carcass recovery and provide insights int
All over the developed world there is a SES gradient in health and mortality for adults. Thesemortality differentials have also widened since the 1970s in the countries for which there aredata. Our knowledge about conditions in the more distant past is much more rudimentary, andwe do not know when and why the mortality gradient emerged. In this paper we studydifferences in life expectancy at age 6
This study examines how organisational actors within a manufacturing firm recognise and navigate AI readiness factors during AI initiatives. Existing research identifies which readiness dimensions matter but offers limited understanding of how these dimensions are recognised and managed in practice. The study was conducted as a single case study of SKF Group, based on nine semi-structured intervie
Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H → ZZ* → 4ℓ decay channel. The proton-proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb−1. The inclusive fiducial cr
Following an increase in Roma migration under the European “freedom of movement” laws, Swedish municipalities initiated more than 80 evictions of informal Roma settlements on the grounds of poor sanitation between 2013 and 2016. These evictions echo policies from earlier in the 20th century, when Roma living in Sweden were often marginalized through the denial of access to water and sanitation fac
The population density concept has emerged as a proposal for the analysis of molecular dynamics results, the key characteristic of population density is the evaluation of the simultaneous occurrence of a set of relevant parameters for a system. However, despite its statistical strength, selection of the tolerance level for the comparison of different models may appear as arbitrary. This work intro
During the last decades, the use of wood as construction material in multi-story buildings has increased in Europe. Compared to conventional concrete buildings, wood buildings are more sensitive to dynamic loading at low frequencies. Also, the response to dynamic loading is in general more difficult to predict for wood buildings, given a certain degree of accuracy. This is a consequence of the com
AbstractModern medicine and health care rely on a variety of diagnostic and therapeutic equipment and methods that involve ionizing radiation. To guarantee quality and the safety of patients and staff, advanced radiation detectors and dosemeters are needed that have low energy and operate with directional independence for X-ray and γ-ray photons. Similar instruments are also of great importance fo
The intestinal dietary fibre degradation and faecal bulking capacity of various bulk laxatives were investigated by means of balance experiments on rats. Nitrogen, fat, and mineral excretion in faeces was also studied. The dietary fibre content of the various bulk laxatives was quite different (in g/kg dry matter): ACO fibre tablets (barley and citrus pulp), 451; Fiberform (wheat bran-based), 817;
We estimate the population of eccentric gravitational wave (GW) binary black hole (BBH) mergers forming during binary–single interactions in globular clusters (GCs), using ~800 GC models that were evolved using the MOCCA code for star cluster simulations as part of the MOCCA-Survey Database I project. By re-simulating BH binary–single interactions extracted from this set of GC models using an N-bo
Purpose of review Chronic breathlessness is a common and distressing symptom globally. It is associated with major adverse health outcomes. This review provides an overview of new evidence about the prevalence of chronic breathlessness in the population. Recent findings A literature search was conducted using MEDLINE database including studies on prevalence of chronic breathlessness and its impact
Advances in open data science serve large-scale model developments and, subsequently, hydroclimate services. Local river flow observations are key in hydrology but data sharing remains limited due to unclear quality, or to political, economic or infrastructure reasons. This paper provides methods for quality checking openly accessible river-flow time series. Availability, outliers, homogeneity and
We discovered structurally novel human calcium-sensing receptor (CaSR) allosteric agonists and compared their pharmacology to phenylalkylamine calcimimetics. 1-Benzothiazol-2-yl-1-(2,4-dimethyl-phenyl)-ethanol (AC-265347) activated CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays with potencies of 30 and 10 nM, respectively. (S)-1-Benzothiazol-2-yl-1-(2,4-di
We consider the analysis of continuous repeated measurement outcomes that are collected longitudinally. A standard framework for analysing data of this kind is a linear Gaussian mixed effects model within which the outcome variable can be decomposed into fixed effects, time invariant and time‐varying random effects, and measurement noise. We develop methodology that, for the first time, allows any
The aeolian deposits of Sweden have received modest attention, despite their usefulness as a palaeoenvironmental archive. Here we present sedimentological information and optically stimulated luminescence (OSL) ages from inland sand dunes in the lowlands of south-central Sweden. Three main lithofacies, each with two subfacies, were identified in the deposits: massive sand, laminated sand and cross
First-order perturbations of homogeneous and hypersurface orthogonal locally rotationally symmetric class II cosmologies with a cosmological constant are considered in the framework of the 1+1+2 covariant decomposition of spacetime. The perturbations, which are of perfect fluid type, include general scalar, vector, and tensor modes and extend some previous works in which vorticity perturbations we
Temporal aspects of ecosystem services have gained surprisingly little attention given that ecosystem service flows are not static but change over time. We present the first systematic review to describe and establish how studies have assessed temporal patterns in supply and demand of ecosystem services. 295 studies, 2% of all studies engaging with the ecosystem service concept, considered changes
Objective. To evaluate the prognostic impact of cytogenetic findings in renal cell carcinoma (RCC). Patients and methods. Tumour cytogenetics, histomorphology, DNA ploidy and S-phase fraction, stage, size, and grade were related to survival in 50 consecutive patients with RCC. The mean follow-up was 3.9 years (median 4.2. range 0-8.8). Results. The predictive probability for recurrence-free surviv
