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Parental feeding practices and associations with child weight status: Swedish validation of the Child Feeding Questionnaire finds parents of 4-year-olds less restrictive.

The Child Feeding Questionnaire (CFQ) assesses parental feeding attitudes, beliefs and practices concerned with child feeding and obesity proneness. While the questionnaire has been developed and primarily used in the U.S., validation studies in other countries are limited. The aim of this study was to examine the psychometric properties of the CFQ among mothers with preschoolers in Sweden and the

The effect of amyloid associated proteins on the expression of genes involved in amyloid-beta clearance by adult human astrocytes

Astrocytes appear to be important mediators in the clearance of amyloid beta1-42 (A beta), the key component of senile plaques characteristic of Alzheimer's disease (AD). Recently, we found the amyloid associated proteins (AAPs) alpha 1-antichymotrypsin (ACT), apolipoprotein J and E (ApoJ and ApoE) and a mixture of serum amyloid P (SAP) and C1q (SAP-C1q) to modify A beta-uptake by human astrocytes

A solubility and surface complexation study of a non-stoichiometric hydroxyapatite

The dissolution and surface complexation of a non-stoichiometric hydroxyapatite (Ca-8.4(HPO4)(1.6)(PO4)(4.4)(OH)(0.4)), (HAP) was studied in the pH range 3.5-10.5, at 25 degrees C in 0.1 M Na(Cl). The results from well-equilibrated batch experiments, potentiometric titrations, and zeta-potential measurements were combined with information provided by Attenuated Total Reflectance Fourier Transform

Secretory and electrophysiological characteristics of insulin cells from gastrectomized mice: Evidence for the existence of insulinotropic agents in the stomach.

Mice were subjected to gastrectomy (GX) or sham operation (controls). Four to six weeks later the pancreatic islets were isolated and analysed for cAMP or alternatively incubated in a Krebs-Ringer based medium in an effort to study insulin secretion and cAMP accumulation in response to glucose or the adenylate cyclase activator forskolin. Freshly isolated islets from GX mice had higher cAMP conten

Antibody Evolution and Repertoire Development

Popular Abstract in Swedish Antikroppar är viktiga beståndsdelar av det naturliga immunförsvaret som skyddar oss mot smittämnen, såsom bakterier och virus. Utvecklingen av olika genetiska och biokemiska teknologier har dessutom möjliggjort användningen av antikroppar för en mängd ändmål, bl a för diagnostik och behandling av infektionssjukdomar och cancer. I denna avhandling, som bygger på fem vetAntibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. Despite tremendous advances in all fields

How to begin treatment in chronic heart failure? Results of CIBISIII

Aims To compare the effect of initial monotherapy with either bisoprolot or enalapril, followed by their combination, on mortality and hospitalization in patients with mild-to-moderate CHF. Methods and results One thousand and ten patients with mild-to-moderate CHF and left ventricular ejection fraction <= 35%, without ACE-inhibitor, beta-blocker, or angiotensin-receptor-blocker therapy were rando

Trade, Competition and Productivity

Popular Abstract in Swedish Avhandlingen består av fyra kapitel som behandlar olika aspekter av internationell handel och dess effekter på konkurrens och produktivitet. Särskilt behandlas effekterna av EU:s expansion och fördjupade integration. Första kapitlet använder den så kallade gravitationsmodellen för att analysera hur integrationsprocessen av de Central- och Östeuropeiska länderna i EU haThis thesis consists of four papers on trade, competition and productivity with particular emphasis on the effects of various aspects of the deepening and widening of the European Union. The first paper Trade Creation, Diversion and Displacement of the EU Enlargement Process provides an assessment of the effects of the EU enlargement process on trade. A new method of estimating the gravity model

Protein Folding Studied by Site Directed Mutagenesis

The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. At low concentrations of denaturant the transition state occurs early in the folding reaction, whereas at high denaturant concentration it moves close to the nati

Min allrabästa och ömmaste vän! Kvinnors brevskrivning under svenskt 1700-tal

Popular Abstract in Swedish Avhandlingen är en studie av kvinnors brevskrivning i Sverige under 1700-talet. Breven är skrivna av ett antal kvinnor från de högre samhällsskikten (adel och borgerskap) under 1780- och 1790-talen. Flertalet av breven är skrivna på svenska, men några också på franska. Huvudsyftet med avhandlingen är att undersöka relationen mellan idén om att kvinnor skrev annorlunda, This dissertation is a study of women's letter-writing in eighteenth-century Sweden. The letters are written by a number of women from the uppper classes (nobility and bourgeoisie) during the last two decades of the eighteenth century. The majority of the letters are written in Swedish, some however in French. The main aim is to examine the relationship between the idea of women as a special kind

Long-Term Risk of Ischemic Stroke After the Cox-Maze III Procedure for Atrial Fibrillation

Background The long-term risk of stroke after surgical treatment of atrial fibrillation is not well known. We performed an observational cohort study with long follow-up after the “cut-and-sew” Cox-maze III procedure (CM-III), including left atrial appendage excision. The aim was to analyze the incidence of stroke/transient ischemic attack (TIA) and the association to preoperative CHA2DS2-VASc (ag

Cognitive and functional changes associated with Aβ pathology and the progression to mild cognitive impairment

Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction are believed to be at high risk for progression to mild cognitive impairment due to Alzheimer's disease (AD). Clinical trials in later stages of AD typically include a coprimary endpoint to demonstrate efficacy on both cognitive and functional assessments. Recent trials focus on cognitively-normal

Donor-recipient size matching and mortality in heart transplantation : Influence of body mass index and gender

Background: The International Society for Heart and Lung Transplantation (ISHLT) guidelines advise against inappropriate weight match (IWM) for heart transplant, defined as donor weight <70% of recipient's weight. Few studies have explored in detail this size-matching recommendation, especially with regard to body mass index (BMI) and gender matching. We aimed to determine whether any difference c

Frenemies in Business: A Case Study on the Phenomenon of Coopetition

Title: Frenemies in Business: A Case Study on the Phenomenon of Coopetition Research Question: What are drivers and challenges behind coopetition, as well as possible outcomes of the relationship? Keywords: Coopetition, Cooperation, Competition, Coopetitive Relationship, Competing Companies, Coopetitors, Coopetition Process, Drivers, Challenges, Possible Positive Outcomes, Possible Negative Out

Who can compete? Analysing the concept of potential competition in reverse patent settlements

After the General Court’s (GC) decision in case T-472/13 H. Lundbeck A/S and Lundbeck Ltd v Commission it seems the concept of potential competition in the context of so-called ‘pay-for-delay’ agreements, or reverse patent settlements, might have been altered; that the bar in order for an undertaking to qualify as a potential competitor might have been lowered. This thesis aims to examine whether

Förbud mot erkännande av utländska barnäktenskap - förenligt med rätten till skydd för familjeliv enligt artikel 8 i Europakonventionen?

I Sverige finns en åldersgräns på 18 år för att ingå äktenskap men det finns ändå barn under 18 år i Sverige som är gifta. De gifta barnen har ingått barnäktenskap utomlands. Äktenskapen har erkänts som giltiga i Sverige om makarna saknade anknytning till Sverige när äktenskapen ingicks. Diskussioner har förts om att regleringen av erkännande av utländska barnäktenskap måste ändras för att skyddetThe age limit for getting married in Sweden is 18 years. Yet there are children under the age of 18 in Sweden who are married. The children have gotten married abroad. The marriages have been recognized as valid in Sweden if the spouses had no connection to Sweden when the marriages were entered. Discussions have been held about that the regulation of recognition of foreign child marriages needs t

Mjukvaruutveckling av ett hastighetsberoende reglersystem för den elektriska styrningen av ett fordon styrt med joysticks

The technology has advanced but the vehicle industry has not evolved at the same pace. Mechanical constructions with a steering wheel are still being used to control the steering of cars. The mechanical construction makes it harder to implement autonomous features, it adds weight and takes up space. It is commonly known that the steering wheel has been along since the early days of the car but is

Functional analysis of cultured retinal cells

Undersökning av näthinneceller odlade på ljuskänsliga nanotrådar Människans sinnen bombarderas ständigt med nya intryck. En stor del av dessa förmedlas via vår syn. Ljus kommer in i ögat och absorberas av ljuskänsliga fotopigment som finns i de yttre segmenten av näthinnans fotoreceptorer. Näthinnan är uppbyggd av flera olika skikt och av flera olika celltyper, både nervceller och stödjande gliacWorldwide, millions of people suffer from retinal degenerative diseases leading to cell death of light absorbing photoreceptors. This results in vision impairment and, in many cases, eventually blindness. A possible solution for patients gone legally blind due to retinal degeneration, is the use of retinal implants. The best performing retinal implants of today, regarding vision acuity, still give

Machine Learning-based MIMO Indoor Positioning

The most widely used positioning system is Global Navigation Satellite System (GNSS), which uses traditional positioning techniques and cannot achieve satisfactory positioning performance in indoor scenarios due to Non-Line-of-Sight (NLoS) transmission. Fingerprinting is a non-traditional positioning technique that is robust to NLoS transmission in indoor scenarios. Moreover, Applying Machine Lear

Arabinoxylan and its potential role in lowering the glycaemic index

Oat (Avena sativa) is a cereal crop rich in dietary fibre, vitamins, antioxidants and other nutrients. It is considered to have higher nutritional values compared to other cereals (Tosh & Miller, 2016). Arabinoxylan (AX) is a hemicellulose naturally abundant in cereal crops. It is a major component of dietary fibre in crops like wheat, barley, rye, maize, rice and oats (Lu et al., 2000). Stu

Effects of Different Laminins on Human Neural Progenitor Cells Cultured in 3D Electrospun Fibers

Inom hjärnforskning används cellkultursbaserade modeller i stor utsträckning som en experimentell plattform, både i grundforskning och läkemedelsupptäckt. Dessa modeller är användbara vid tidig utvärdering av en potentiell läkemedelskandidat. Eftersom nya läkemedel tar extremt mycket tid och pengar att utveckla, vore en så exakt modell som möjligt att föredra.1 En viktig fråga i upptäckt och utvA low success rate of drug candidates in clinical trials, and especially in brain research, motivates development of better screening models. Hence, in neuroscience and many other fields of Life Science, development of more physiological relevant experimental cell-based models is motivated. It’s believed that more in vivo-like models will give a better outcome in drug discovery- and development. H