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Findings in previous studies have suggested nitric oxide (NO) to be a regulator of mucociliary activity in the upper airways. The aim of the present investigation was to study whether a correlation exists between the nasal NO concentration and mucociliary function in patients suffering from respiratory tract diseases such as chronic sinusitis or recurrent pneumonia. Nasal NO was measured with a ch

The synthesis and contents of extracellular non-collagenous matrix macromolecules was studied in early and late human osteoarthritic (OA) cartilage obtained at surgery for sarcomas in the lower extremities (normal and early OA) or for total knee replacement (late stage OA). The early OA samples were those that had some fibrillation in the joint by visual examination. One group had fibrillation in

Atmospheric deposition of N and S appears to have caused nutrient imbalance in Norway spruce stands in southern Sweden. This calls for a change of forest management to procedures that promote nutrient balance. Studies have shown lower soil acidity in Norway spruce/deciduous mixed stands than in spruce monocultures, but the tree nutrient status in such mixtures has not been much investigated so far

Protocols used for generation of mesencephalic dopamine (mesDA) neurons from stem cells, or fetal brain tissue, invariably result in cell preparations that are highly mixed in composition, containing mesDA neuron precursors in various states of fate commitment and differentiation. For further optimisation and refinement of these procedures it is essential to determine the optimal stage of developm

PURPOSE: To evaluate accuracy and noise properties of a novel time-resolved, three-dimensional, three-directional phase contrast sequence with variable velocity encoding (denoted 4D-vPC) on a 3 Tesla MR system, and to investigate potential benefits and limitations of variable velocity encoding with respect to depicting blood flow patterns. MATERIALS AND METHODS: A 4D PC-MRI sequence was modified t

We and others have previously shown that inhibitor containing plasma from patients with congenital haemophilia A sometimes reacts less with von Willebrand factor (VWF) containing concentrates compared with highly purified plasma-derived or recombinant factor VIII (FVIII) concentrates. To further substantiate the haemostatic role of a variation in inhibitor reactivity with different FVIII concentra

Objective. To evaluate barriers to adherence to hypertension guidelines among publicly employed general practitioners (GPs). Design. Questionnaire-based survey distributed to GPs in 24 randomly selected primary care centres in the Region of Skåne in southern Sweden. Subjects. A total of 109 GPs received a self-administered questionnaire and 90 of them responded. Main outcome measures. Use of risk

Summary Inherited deficiencies in components of the classical complement pathway are strong disease susceptibility factors for the development of systemic lupus erythematosus (SLE) and there is a hierarchy among deficiency states, the strongest association being with C1q deficiency. We investigated the relative importance of the different complement pathways regarding clearance of apoptotic cells.

BACKGROUND: Constitutive promoters that ensure sustained and high level gene expression are basic research tools that have a wide range of applications, including studies of human embryology and drug discovery in human embryonic stem cells (hESCs). Numerous cellular/viral promoters that ensure sustained gene expression in various cell types have been identified but systematic comparison of their a

Many axons follow wave-like undulating courses. This is a general feature of extracranial nerve segments, but is also found in some intracranial nervous tissue. The importance of axonal undulation has previously been considered, for example, in the context of biomechanics, where it has been shown that posture affects undulation properties. However, the importance of axonal undulation in the contex

The mutation G17736A/Val107Val (silent) was found in five of a total of 86 families with haemophilia B in Sweden. It is unlikely that five families with analogous clinical expression will have the same polymorphism, which is not found in other patients or normal subjects, or that they will be the only families in the population without any other causative mutation. All affected individuals in the

A low-diversity halysitid-heliolitid autobiostrome from the Late Wenlock Halla Formation at Blåhäll 1, Gotland, indicates a brief period of particular environmental conditions. The reef is 0.3–0.5 m thick, internally without bedding structures, and had a sheet-like distribution on a low-relief soft-bottom, in marginal platform, graptolitiferous strata (height-width ratio is 1:900 in outcrop). The

This paper consists of a literature study and laboratory experiments of magnesium oxide boards, from Swedish suppliers, that is a part of a larger research project. Lately the boards have become known for the way they absorb moisture which has led to damage on adjacent materials. The boards are inorganic and are marketed as moisture proof. The purpose of the larger research project is to identify

Återställning av alvarlandskapet – en studie om Degerhamns kalkstensbrott När ett stenbrott avslutas börjar arbetet med att så gott som möjligt återskapa det landskapet som fanns innan brytningen. Min studie har undersökt hur detta ska gå till i ett kalkstensbrott i Degerhamn på södra Öland. Detta är en mycket viktig fråga då området på södra Öland internationellt sett är en mycket unik naturtypWhen a quarry closes measurements must be taken to recreate the landscape that originally was there. Old quarries are filled with water and are called artificial lakes. The aim of the study is to compare the water quality in three artificial lakes within a limestone quarry in Degerhamn, Öland with an alvar lake outside the quarry, in order to aid the restoration of the original landscape. The goal

The public sector in Sweden has since the 1980´s looked for inspiration from businesses and corporations in the organization of their work. This due to the emergence of a management trend known as new public management. One effect has been a spread of the concept of lean in multiple public sector organizations all over the country. Lean is a concept and method used to achieve efficiency and qualit

The objective of this essay is to investigate if the performance of an Exchange-Traded Fund (ETF) share has an impact on the probability of closure of the same Exchange-Traded Fund. A great number of ETFs closures occurred in the last two years and the number of these closed ETFs represent a relevant percentage of the total number of ETFs that have been liquidated since this type of shares came to

In this Master's Thesis x-ray tomography was used during tensile experiments on paperboard to study delamination and cohesive failure. Digital volume correlation of the x-ray tomograph images enabled quantitative analysis of strain fields. Tensile experiments on different specimen geometries were also conducted to investigate how the geometry affected the response of the specimens during load