Filetype
Purpose: Prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) is used for (re)staging prostate cancer (PCa) and as a biomarker for evaluating response to therapy, but lacks established response criteria. A panel of PCa experts in nuclear medicine, radiology, and/or urology met on February 21, 2020, in Amsterdam, The Netherlands, to formulate criteri
Assessments of long-term changes of air quality and global radiative forcing at a large scale heavily rely on satellite aerosol optical depth (AOD) datasets, particularly their temporal binning products. Although some attempts focusing on the validation of long-term satellite AOD have been conducted, there is still a lack of comprehensive quantification and understanding of the representativeness
Hearing is our second most important sense. The main focus of a surveillance camera is obviously the video but the audio shouldn't be neglected. It is possible to hear what the camera can't see and what is said in a conversation can't be showed in a video. Therefore there are good reasons to always try and achieve the best audio possible. This is not an easy task since cameras are oper
The science of climate change stipulates that fossil fuels must be kept in the ground in order for earth's global temperature to stay below the 1.5 degrees' Celsius increase pre-ordained as safe for continued human civilization, and to avoid catastrophic natural, social, and economic disasters. Although this is a scientifically proven and agreed upon, governments around the world continue
Background: There is a need for a rapid and cost-effective evaluation of the effects of different human papillomavirus (HPV) vaccination strategies. Sexually active adolescents are a preferred target group for monitoring, as effects on HPV prevalence would be measurable shortly after implementation of vaccination programs. Methods: The Swedish Chlamydia trachomatis testing program offers free Chla
Popular Abstract in Swedish Människan har alltid exponerats för joniserande strålning från radioaktiva ämnen i naturen och i sin egen kropp, samt från kosmisk strålning. Summan av exponeringen från dessa strålkällor blir ungefär 1 mSv per år. Till detta kommer exponering av lungor och luftvägar från radon och radondöttrar, särskilt i inomhusluft. Som jämförelse kan nämnas att en tandröntgen ger enA quarter of a century has elapsed since the catastrophe at the nuclear power plant in Chernobyl. The radioactive fallout affected all the European countries and most severely the three countries of Belarus, Russia and Ukraine. In the aftermath of this devastating event, the scientific knowledge on the various radiological impacts of such a large scale accident and means to remediate these impacts
Popular Abstract in Swedish Övervikt och fetma ökar i hela världen och fortfarande vet ingen exakt varför vi äter mer än kroppen behöver. En rådande teori är att den västerländska dieten till stor del innehåller ”supervälsmakande” mat med mycket socker och fett som godis, glass, chips och feta såser. Sådan mat ökar risken för överkonsumtion och kan därför leda till övervikt och fetma. Att öka mättWestern diet contains a high proportion of palatable food, rich in refined carbohydrates and fat, that subsequently increases the risk of overconsumption and possibly leads to overweight and obesity. Therefore an approach to strengthen the inherent satiety for fat can be used to prevent overconsumption. Thylakoid membranes isolated from the chloroplast of green leaves have been found to reduce the
The purpose of this essay was to investigate the opinions of young people, age 14-16, at a school in a middle-sized city in Sweden, concerning narcotics. The questions we asked ourselves were; -What are young peoples' ideas of narcotics? -What do young people imagine when they think of a drug addict? -What reasons do young people give to start using narcotics? -What gender-related opinions
This thesis investigates all aspects of quality and evaluation issues concerning collections of Internet links in public libraries today and in the future. We have studied central theories concerning quality in general as well as quality aspects regarding the Internet and Internet links. In addition to this we have made three case-studies involving the development of collections of Internet links
This thesis aims to offer insights into the initiation and development of modern (rural) bioenergy systems. For this reason, the thesis explores the formation, evolution and regional effects of three bioenergy projects ? a biodiesel cooperative, a biomass district heating plant and a biogas plant ? that are co-located within the small rural community of Mureck, in Austria. It finds that the three
Targeted radionuclide therapy is an emerging potent therapeutic strategy in oncology. The cell surface antigen CD44v6 is a potential pan-cancer target for radionuclide therapy. This study aimed to evaluate the therapeutic efficacy, biodistribution, dosimetry, and safety profile of AKIR001, an antibody targeting CD44v6 labeled with 177Lu. Methods: The biodistribution and preclinical dosimetry of [1
Introduction: Non-suicidal self-injury (NSSI) is often met with stigma, which can deter individuals from seeking help. While most research on NSSI stigma has focused on clinical settings, the attitudes of those most likely to receive an NSSI disclosure, such as peers, friends, and family, remain underexplored. Building on qualitative findings that positive disclosure experiences can foster support
Ultrasound is a promising neural stimulation modality, but an incomplete understanding of its range and mechanism of effect limits its therapeutic application. We investigated the modulation of spontaneous hippocampal spike activity by ultrasound at a lower acoustic intensity and longer time scale than has been previously attempted, hypothesizing that spiking would change conditionally upon the av
D-dimer has been proven to be an excellent rule-out marker for acute type A aortic dissection (ATAAD) with a sensitivity exceeding 95% while specificity remains low. We hypothesized that the addition of fibrinogen, which is decreased in ATAAD patients due to consumption coagulopathy, would increase predictive ability. This was an exploratory, retrospective, single-region, observational study compa
OBJECTIVE: In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progression, indicating that metabolic changes may be involved in disease pathogenesis. Underlying mechanisms of metabolic changes in HD are not fully known,
This study aimed to analyze stressors to which medical staff is vulnerable due to the coronavirus disease 2019 (COVID-19) pandemic. It also imposes a hierarchy on complex relations among stressors for excavating underlying structure and builds a model of interrelationships contrasting reality. The design of this study comprises a literature survey, data collection from primary sources, and analysi
Extending beyond previous research biases towards large cities or analyses based largely on one type of urban agriculture (UA) (such as market gardening, or home gardening), this research aimed to investigate all forms of UA within two intermediate-sized Ghanaian cities (Techiman and Tamale). Where was being farmed? For whom, and why? The paper considers how findings compare to Ghana's larger citi
Aggregated α-synuclein (α-syn) is the main constituent of Lewy bodies, which are a pathological hallmark of Parkinson’s disease (PD). Environmental factors are thought to be potential triggers capable of initiating the aggregation of the otherwise monomeric α-syn. Braak’s seminal work redirected attention to the intestine and recent reports of dysbiosis have highlighted the potential causative rol
Much of the income equalization that took place during the first half of the twentieth century was driven by shifts in the shares of the incomes of the rich, such as the top 1 percent. But the available studies using tabulated data have not been wholly able to account for the relative decline in top earners’ incomes. In this paper, we present the first evidence on the composition of the top groups
Fire regimes across the world are expected to be altered by continuing variations in socio-economic conditions and climate. Current global fire-vegetation models are able to represent the present-day fire activity, but it is unclear how well they can simulate past or future scenarios. Here we use sedimentary charcoal-based biomass burning reconstructions to evaluate fire probability and total carb
