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Popular Abstract in Swedish Förlossnings- och barnläkare har i många år sökt efter ett instrument för utvärdering av det nyfödda barnets hälsotillstånd. Virginia Apgar introducerade 1953 ett poängsystem som bygger på en subjektiv bedömning av barnets hudfärg, hjärtfrekvens,reflexer/retbarhet, muskeltonus och andning. Koncentrationen i blodet av olika gaser, syror och baser speglar också det nyföddAcid-base status in umbilical cord blood is an objective measure of the fetus’ exposure to and ability to handle hypoxia. The objective of this thesis was to clarify some of the methodological pitfalls in interpreting umbilical cord blood gases and lactate values at birth. Study I pinpoints the methodological confounding in calculating base deficit (BD) with algorithms used in different brands of

This is a thesis on the Swedish writer Vilhelm Moberg (1898–1973) and his renowned novel cycle about Swedish emigrants to the U.S.: Utvandrarna (1949), Invandrarna (1952), Nybyggarna (1956) and Sista brevet till Sverige (1959). The novels, set in the mid 19th century, describe Swedish emigration to North America through the main characters of Karl Oskar, Kristina, Ulrika and Robert from the parish

Popular Abstract in Swedish Min avhandling består av sex delarbeten som redovisar olika undersökningar av ett värmestabilt enzym (xylanas). Detta enzym är isolerat från en bakterie (Rhodothermus marinus) som lever i varma källor (vid 55-77 °C) och enzymet förväntas alltså fungera vid dessa temperaturer. Enzymets uppgift i bakterien är att förse den med lagom långa kolhydratmolekyler som bakterien A gene encoding a multidomain xylanase from the thermophilic bacterium Rhodothermus marinus has been cloned, sequenced and produced in Escherichia coli . The gene product was found to be a 109 kDa protein consisting of five domains. The catalytic domain and the two polysaccharide binding domains (PBD, previously called carbohydrate binding domains) have been cloned and produced separately for func

Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. Due to improved hydrolytic stability, lactam (inner amide) analogues of gangliosides sho

This thesis consists of four papers A, B, C and D. Paper A and B treats the simulation of stochastic differential equations (SDEs). The research presented therein was triggered by the fact that there were not any efficient implementations of the higher order methods for simulating SDEs. So in practice the higher order methods required at least the same amount of work as the Euler method to obtain

Popular Abstract in Swedish Men älskar du honom? Så frågar en ung flicka på 1820-talet sin syster Henrietta som just skall gifta sig. Nej det gör Henrietta inte men hon böjer sig för den krassa verkligheten, behovet att bli försörjd. Den stillsamma frågan anger något som kan tolkas som en tyst revolution: övergången från en äldre syn på äktenskapet som ett ekonomiskt kontrakt till en uppfattning aThe main theme of this dissertation is the question of how young women in the early middle class handled the new demands for marriage based on love instead of on judgements of moral, economy and status. Another theme is the education of these middle class girls around 1800 and the question how this new education interacted with the new demands for love marriage. The German social historian Ulrike

The objectives of this dissertation are 1) to describe what child protection services actually do when assessing risk and deciding on interventions, and 2) to analyze this practice in the light of institutional expectations, organizational demands and professional technology. The field work was carried out in two Danish municipal social service agencies. Data consist of records on families subject

The present study aimed to investigate the relationship between growth rate, final mass, and larval development, as well as how this relationship influences reproductive trade-offs, in the context of a gregarious life-style and the need to keep an optimal group size. We use as a model two sympatric populations of the pine processionary moth Thaumetopoea pityocampa, which occur in different seasons

Background: Prostate cancer patients have an increased risk of fractures as a consequence of skeletal metastases and osteoporosis induced by endocrine treatment. Data on incidence of fractures and risks in subgroups of men with prostate cancer are sparse. Our aim with this study is to report the risk of fractures among men with prostate cancer in a nationwide population-based study. Patients and m

Background: Regional myocardial function is typically evaluated by visual assessment by experienced users, or by methods requiring substantial post processing time. Visual assessment is subjective and not quantitative. Therefore, the purpose of this study is to develop and validate a simple method to derive quantitative measures of regional wall function from velocity encoded Cardiovascular Magnet

BACKGROUND: The aim of the current study was to investigate the possibility of increasing the maximal tolerated dose (MTD) of a tumor-selective radiolabeled antibody when radioimmunotherapy (RIT) is combined with extracorporeal depletion of radioimmunoconjugates from the circulation. Furthermore, the authors evaluated whether this increase in dose improved the therapeutic effect on solid manifest

Malarial infection is associated with complex immune and erythropoietic responses in the host. A quantitative understanding of these processes is essential to help inform malaria therapy and for the design of effective vaccines. In this study, we use a statistical model-fitting approach to investigate the immune and erythropoietic responses in Plasmodium chabaudi infections of mice. Three mouse ph

Background: High plasma copeptin (copeptin), the C-terminal fragment of arginine vasopressin pro-hormone, has been associated with the metabolic syndrome (MetS), diabetes mellitus (DM) development and nephropathy. Here we tested whether elevated copeptin level is associated with later development of the MetS, its individual components and microalbuminuria. Methods: We analysed copeptin at baselin

Aims/hypothesis Latent autoimmune diabetes in adults (LADA) is phenotypically a hybrid of type 1 and type 2 diabetes. Genetically LADA is poorly characterised but does share genetic predisposition with type 1 diabetes. We aimed to improve the genetic characterisation of LADA and hypothesised that type 2 diabetes-associated gene variants also predispose to LADA, and that the associations would be s

Magnetotactic bacteria (MTB) are known to biosynthesise single-domain magnetite (Fe3O4) for geomagnetic navigation and their relict magnetosomes (called magnetofossils) can control the magnetic properties of lake and marine sediments. Magnetotactic bacteria also produce greigite (Fe3S4) magnetosomes but, compared to those made of magnetite, relatively little is known about the sedimentary environm

Hydrothermal alteration resulting in albitization and quartz dissolution has been identified in Paleoproterozoic metagranites down to - 1000 m elevation at Forsmark, Sweden. The alteration features were discovered during investigations to locate a site for the disposal of spent nuclear fuel in a deep geological repository. In general, albitization occurs extensively, but it is also observed locall

Popular Abstract in Swedish Akut bukspottkörtelinflammation (akut pankreatit ? AP) är en akut inflammation som kan resultera i en självdestruktiv process i bukspottkörteln. 70-80 % av fall med AP klassificeras som lätta-måttliga och är självbegränsande, medan cirka 20 % klassas som svåra och karakteriseras av utvecklingen av nekros (vävnadsdöd) i bukspottkörteln och omkringliggande vävnad, utvecklIn acute pancreatitis (AP), lung injury is an early occuring and important part of the multiple organ dysfunction syndrome. The mechanisms underlying the development of lung injury though still largely remains unclear. The aim of the present study was to study mechanisms of the systemic and secondary pulmonary inflammation and injury, with an emphasis on the involvement of immune cells, inflammato

Introduction: Risedronate, a bisphosphonate for treatment and prevention of osteoporosis, has been shown in several clinical trials to reduce the risk of fractures in postmenopausal women with osteoporosis. The cost-effectiveness of risedronate treatment has previously been evaluated within different country settings using different model and analysis approaches. The objective of this study was to

In this paper a study of a career planning project launched by the Swedish National Tax Board is reported. The project, named Propeller, was initiated in 1998 as a joint endeavour among three agencies: the Swedish National Tax Board, the Regional Stockholm Tax Office and the Enforcement Authority. The intention was to create a common micro labour market in order to encourage employees to become mo

Popular Abstract in Swedish Köpenhamnsevangeliariet skrevs och illuminerades i England omkring år 1000, och intar en viktig position i konsthistorien genom sina ikonografiska likheter med det 300 år äldre Lindisfarneevangeliariet. I föreliggande avhandling behandlas handskriften i sin helhet med avseende på dess framställning och senare historia, men den huvudsakliga analysen rör bildernas stilistThe subject of this thesis is the Copenhagen Gospel Book , written and illuminated in England c 970 with additions from c 1020. The thesis is divided into three main parts focusing on different aspects of the manuscript. The first part deals with problems concerning provenance, palæography, later additions and the physical architecture of the manuscript. The author questions the opinion that the m