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An important role for WNT-5A is implicated in a variety of tumors, including breast carcinoma. We previously showed that WNT-5A signaling inhibits migration and metastasis of breast cancer cells, and that patients with primary breast cancer in which WNT-5A was expressed have a better prognosis. Despite the fact that RhoGTPase Cdc42 is commonly associated with increased cell migration, we here show

Epidemiology studies suggested that low birthweight was associated with a higher risk of hypertension in later life. However, little is known about the causality of such associations. In our study, we evaluated the causal association of low birthweight with adulthood hypertension following a standard analytic protocol using the study-level data of 183,433 participants from 60 studies (CHARGE-BIG c

This LUii report presents a research review of the field of over-indebtedness and consumption patterns in digital society, which addresses phenomena such as e-commerce, smart phones and their role in consumption and credit, new methods of payment, debt-incurrence and more. The research review has been produced by researchers at Lund University on behalf of the Swedish Enforcement Authority, why it

Atmospheric new particle formation (NPF) is an important phenomenon in terms of global particle number concentrations. Here we investigated the frequency of NPF, formation rates of 10 nm particles, and growth rates in the size range of 10–25 nm using at least 1 year of aerosol number size-distribution observations at 36 different locations around the world. The majo

Characterization of land cover change in the past is fundamental to understand the evolution and present state of the Earth system, the amount of carbon and nutrient stocks in terrestrial ecosystems, and the role played by land-atmosphere interactions in influencing climate. The estimation of land cover changes using palynology is a mature field, as thousands of sites in Europe have been investiga

Chinese furniture industry is facing serious problem of limited virgin resources, environmental pollution and has an overall low profit rate. Implementing the circular economy in the industry is necessary and will contribute to its economically sustainable growth. Exploring and understanding these limited business models and conditions under which resource efficiency can be enabled and secured, es

Author: Hanna Hansson Title: A problem in alteration - A study of the construction of men's violence against women as a social problem [Translated title] Supervisor: Stig Linde Assessor: Ingrid Sahlin The purpose of this study was to examine the constrution of men’s violence against women. More specific, the aim was to look at the consequenses of these changes in the construction of victims a

The interest for renewable energy within Australia is growing and the New South Wales (NSW) Government has committed to a Renewable Energy Target scheme of 20 percent renewable energy by 2020. Wind energy is a mature renewable energy resource, which has been successfully deployed for electricity generation around the world. It is further believed to be a viable option to help expand the renewable

Hybrid 56 (H56) is a new vaccine candidate against pulmonary tuberculosis (TB) developed by Staten Serum Institut (SSI) and currently being tested in clinical trial phase IIa. The vaccine consists of three mycobacterial proteins ESAT-6, Ag85B, and Rv2660c that are fused together in a poly-protein. When formulated in a cationic adjuvant (CAF01), Hybrid56 has shown consistent protective efficacy in

Sedan urminnes tider har man vetat om att det finns ljusa kroppar på himlen som rör sig ovanligt fort. Grekerna döpte dessa till vandrare, ett ord som på grekiska uttalas väldigt likt planet. Planeterna har studerats i århundraden och bara de senaste två decennierna har vi ökat från våra egna åtta planeter till flera tusen nya planeter kallade exoplaneter, planeter runt andra stjärnor än våran egeData from NASA's Kepler space telescope, which searches for exoplanets via the transit method, produced 1108 new planetary candidates in 2013 with a total of 91% being smaller than Neptune in size. These were mostly super-Earths, terrestial planets between Earth and Neptune in size, with orbits around 10 days. In order for any theory of planet formation to be valid it must be able to account

Uppsatsens syfte är att undersöka huruvida kulturegendom tillmäts ’tillräckligt skydd’ av internationell rätt i väpnade konflikter, med betoning på den juridiska grunden för att åtala förstörelse av kulturarv som ett krigsbrott under internationell straffrätt. Jag undersöker hur de mest relevanta traktaterna i internationell rätt har uppstått sedan antagandet år 1954 av Haagkonventionen för skyddThe purpose of this thesis is to examine whether cultural property is attributed ‘sufficient protection’ by international law in armed conflicts, with an emphasis on the legal basis for prosecuting its destruction as a war crime under international criminal law. I research how the most relevant treaties in international law have emerged since the adoption of the Convention for the Protection of Cu

County museums were for a long time one of the main actors in Swedish cultural resource management (CRM) archaeology. In the late 1990s, however, Swedish CRM archaeology faced a new system: a tender-alike procedure. The introduction of competition into CRM archaeology has produced a series of positive, as well as a series of negative, consequences. One effect is that several county museums have ce

Bluvisions IoT-system har varit huvudfokus under utredningen av om IoT(Internet of Things) är lönsamt att implementera på framtidens Valmetmaskiner. Från början så skulle projektet avgränsas till pressning, kräppning och upprullning men under examensarbetets start fick Valmet svårt att hitta orsaken till varför en ny komponent hade havererat. Havereringen tros ha haft ett samband med höga vibratioBluvision’s IoT-system has been the focus during the investigation if IoT (internet of things) is something that can be implemented on future Valmet machines. From the beginning the bachelor thesis was restricted to press, creping and turn-up. During the initial phase of the bachelor theses start Valmet had problem finding out why a new component had failed. Therefore, it was more valuable for Val

Liten blomma i backen, formad av bondens blod, svett och tårar En bit innan semesterparadiset Smögen, ligger en liten ö med mångårig historia. Här har marken odlats under många hundra år. På sommaren slåttrade man gräset, bar det till höbalar, och korna betade lojt på med utsikt över klipporna och havet. Störningarna var stora på gräsmarkerna, lien skar av växterna och korna betade, för många växWith the gain of productivity in farming the last decades, there has been great loss in species richness. Many plant species that have evolved and adapted alongside to traditional farming and benefiting to the managed land use, are now disappearing in great numbers. Three thirds of Sweden’s endangered plant species are those who thrive in managed grasslands like meadows and grazing areas. The trad

I Sverige har efterlevandeskyddet för sambor varit en omdebatterad fråga under de senaste decennierna. Inte minst aktualiserades frågan till följd av tvisten som uppstod efter författaren Stieg Larssons bortgång. Trots utredningar och medial uppmärksamhet har det emellertid inte skett några förändringar i den svenska rätten. Samtidigt har det i både Danmark och Norge, två grannländer med i övrigt In Sweden there has been a longstanding debate in regards to the legal provisions for surviving cohabitants. The question gained attention in particular after the sudden passing of the famous swedish author, Stieg Larsson, and the following legal dispute. In spite of the public attention and public enquiries no significant changes to the Swedish legislation has been undertaken. In the meanwhile bo

Sidi Bouzid, Tunisia is an inland governorate in Tunisia that has undergone a rapid agricultural and urban development since the Tunisian independence in 1952 from being a rural and largely nomadic region into a hub of irrigated agriculture. In 2010 Mohamed Bouazizi sparked the Tunisian revolution by lighting himself on fire int he city of Sidi Bouzid, with some blaming the inequality and water sc

Ever since the murder of the Swedish Prime Minister Olof Palme in February 1986, many different theories about who the killer could be have been created and discussed. One of the more intensely discussed theories is the “police-conspiracy theory”. In this thesis I investigate how this theory became a kind of public knowledge in the years after the assassination. Using a theoretical framework base

In their work, military personnel will face risks and threats: during deployments in ambiguous high risk mission contexts abroad, but also in peacetime in the Netherlands during training programs and exercises or national support operations. In all these contexts, it is crucial that team members speak up: sharing concerns, asking questions and providing ideas supports effective team decision makin

Purpose – The purpose of this master thesis is to test the applicability of the dashboard development procedure by Vilarinho, Lopes and Sousa (2017) in the application case of a single case study for a redesign of a production dashboard. In doing so a practical new dashboard layout shall be reached, which considers the needs of all dashboard users. Design/methodology/approach – This thesis was co

De flesta av oss associerar nog kemikalier med något negativt, men sanningen är att kemikalier utgör en förutsättning för mycket av den välfärd som vi ser idag. Tvärtemot vad man kan tro, så är det inte bara i produkter som plast, färg, lösningsmedel, med mera som dessa förekommer, utan även i produkter som räddar liv, till exempel i utrustning inom sjukvården och för vattenrening. Därför är de meThe production and use of chemicals has grown exponentially over the past 50 years. Although the knowledge of hazards and risks associated with chemicals towards humans and the environment has increased, we know frightenedly little about how dangerous these might become when part of finished products. Companies now need to be more concerned about which chemicals exist in their products. For the co