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Circulatory failure is considered one of the entities of the post cardiac arrest syndrome contributing to poor outcome. It is reported at 15-70% of all patients successfully resuscitated from out-of-hospital cardiac arrest (OHCA). The pathophysiologic mechanism is attributed to limitation of cell metabolism due to inadequate supply of oxygen, caused by pump or conduction failure within the cardiov
1 BACKGROUNDWeak expression of ABO antigens is encountered in the clinical laboratory occasionally, and subgroups of A are more commonly observed in Europeans than subgroups of B. To date, weakly expressing B variant phenotypes have been associated with 38 different alleles according to ISBT (https://www.isbtweb.org/resource/001aboalleles.html). This number is an underrepresentation since there ha
Saliva plays a crucial role in maintaining oral health through its physical and chemical properties that provide various protective functions. One of its essential components is the human host defense peptide LL-37, which is produced by immune cells and epithelial cells, and participates in the first line of defense against pathogens. LL-37 is a potent antimicrobial agent against both gram-positiv
In order to increase the competitiveness of timber as a building material in outdoor applications, durability and dimensional stability must be ensured. Acetylation enables an environmentally friendly way to increase both durability and dimensional stability of wood, without introducing harmful substances to the environment. The focus of the present research is to examine the possibility of adding
Background and ObjectivesRecently, the US Food and Drug Administration approved the tau-binding radiotracer [18F]flortaucipir and an accompanying visual read method to support the diagnostic process in cognitively impaired patients assessed for Alzheimer disease (AD). Studies evaluating this visual read method are limited. In this study, we evaluated the performance of the visual read method in pa
Introduction: Ischemic stroke incidence appears to have decreased during the last decades, but most studies focus on the first-ever events and epidemiological data on recurrent stroke are scarce. The aim of our study was to investigate trends in incidence, risk factors, and medication in patients with first-ever and recurrent ischemic stroke between 2010 and 2019 in Sweden. Methods: We included pa
År 2011 infördes entreprenörskap i den svenska skolans läroplaner. På 1980-talet ansågs dock utbildningsorganisationen Ung Företagsamhet (UF), som fokuserar på entreprenörskapsutbildning för ungdomar, vara ideologiskt kontroversiell. Under loppet av 30 år har synen på entreprenörskap och UF:s status förändrats i grunden. Denna avhandling undersöker hur och varför entreprenörskap blev ett kunskapsoIn 2011, entrepreneurship was added to the curricula of Swedish schools at all levels. In the 1980s, however, the educational organization Junior Achievement (JA), that focuses on entrepreneurship education for young people, was considered ideologically controversial. Over the course of 30 years, the view of entrepreneurship and the status of JA has changed fundamentally. This thesis investigates
Intracortical neural probes have in the last couple of years been developed from stiff single probes to stiff multi-electrode neural probes to flexible multi-electrode neural probes. One reason for the change in design is that more than one recording/stimulation electrode, as in the case with a single wire, is needed for more advanced studies. The stiff multi-electrode probes were fabricated using
The long poem Skördarne (The HArvest) by johan Gabriel Oxenstierna (1750-1818) was an attempt to do for the Swedish what Virgil had don for the Roman Countryside in his Georgics. However, "georgic poetry" was seldom recognised as a distinct genre by the classical system of poetics, and its relation to neighbouring genres were often unclear. The present study seeks to place Oxenstierna's poem in th
Popular Abstract in Swedish Uppskattningsvis 30 % av befolkningen i industrialiserade länder drabbas varje år av förgiftningar och infektioner överförda via livsmedel och frekvensen i utvecklingsländer tros vara högre. För att kunna producera säker mat behövs mer kunskap om vilka egenskaper hos livsmedelsburna patogener, dvs. sjukdomsframkallande mikroorganismer som gör oss sjuka. Dessa egenskaperThe development of new, minimally processed food products challenges traditional concepts of food safety. How pathogenic bacteria behave in these new matrices is not known. To fill this knowledge gap and enable the production of food that is safe for the consumer, more information on virulence expression of pathogens in food matrices is required. In this thesis, the impact of environmental factors
In current recommendations from FAO/WHO, foods that elicit low glycaemic responses and thus have low glycaemic indices (GIs) are advocated. The rationale for this recommendation is that low-GI diets have been shown to reduce risk factors for e.g. type II diabetes and cardiovascular disease. A major problem in this context is that most important starch rich staple foods in our diet, such as potato
The use of Penman-Monteith (PM) equation in thermal remote sensing based surface energy balance modeling is not prevalent due to the unavailability of any direct method to integrate thermal data into the PM equation and due to the lack of physical models expressing the surface (or stomatal) and boundary layer conductances (g(S) and g(B)) as a function of surface temperature. Here we demonstrate a
Dactylorhiza majalis subsp. sphagnicola is an allotetraploid marsh orchid derived from parents closely similar to present-day D. incarnata and the western European form of D. maculata subsp. maculata, suggesting that it has a postglacial origin. It extends from northwestern continental Europe into areas formerly covered by the Weichselian ice sheet in mid-Scandinavia. Here, we studied the variatio
Popular Abstract in Swedish Denna avhandling är inriktad på metoder för att förbättra och utvärdera infrastrukturer för geografiska data (eng. Spatial Data Infrastructure). Syftet har varit trefaldigt: att utveckla ett ramverk för hantering och utvärdering av en infrastruktur, att förbättra tillgängligheten av geografiska data i en infrastruktur, och för att förbättra kartografi i visningstjänsterThis thesis mainly focuses on methods for improving and evaluating Spatial Data Infrastructures (SDIs). The aim has been threefold: to develop a framework for the management and evaluation of an SDI, to improve the accessibility of spatial data in an SDI, and to improve the cartography in view services in an SDI. Spatial Data Infrastructure has been identified as an umbrella covering spatial data
Popular Abstract in Swedish Antagandet att människor är förmögna att kontrollera och avsiktligt glömma oönskade minnen har varit kontroversiellt allt sedan Freud (1915/2000) först antog den typen av psykologisk process. Men aktuell experimentell forskning ger ökat belägg för att avsiktligt undertryckande av oönskade minnen faktiskt kan leda till senare glömska (cf. Levy & Anderson, 2002). ResuForgetting can be highly functional when unwanted or irrelevant memory representations interfere with cognitive or motivational goals. Current theory assumes that forgetting can be brought about by the intentional or unintentional inhibition of interfering memory representations. In four studies, the present thesis investigated this claim by employing behavioral testing, and neuroimaging methods b
This thesis focuses on multivariate multilevel modeling of panel data originated from smallholder farm surveys in Sub-Saharan African (SSA) countries and Vietnam to investigate driving forces in maize and rice production in SSA and diversification of farms in the rice sector in Vietnam. We also present and evaluate different tests for endogeneity in explanatory binary variables in multivariate lin
The APOE4 allele is the strongest genetic risk factor for sporadic Alzheimer's disease (AD). While APOE4 is strongly associated with amyloid-beta (Aβ), its relationship with tau accumulation is less understood. Studies evaluating the role of APOE4 on tau accumulation showed conflicting results, particularly regarding the independence of these associations from Aβ load. In this study, we examined t
Ukraine is at a cross roads. Several important decisions are needed to be made and carried out in a short time to secure the future of their in many cases broken and inefficient district heating systems (DHS), which heat the homes and offices of millions Ukrainians today. To make matters worse they have foreign interests panting down their necks with demands of payments regarding gas bought and im
I Sverige har vi idag en civilrättslig diskrimineringslag (2008:567) som täcker en rad samhällsområden och sju olika diskrimineringsgrunder. Denna lag är resultatet av att en samling lagar mot diskriminering som kom till runt millennieskiftet slogs samman och delvis förändrades. Lagen innehåller diskrimineringsförbud och aktiva åtgärder och dess syfte är att ”motverka diskriminering och på andra sSweden currently has a civil law against discrimination (2008:567) that covers several aspects of society and seven different grounds for discrimination. This law is the product of the consolidation – and to some extent modification – of a number of laws primarily passed between 1999 and 2006. The law contains prohibitions against discrimination and proscribes certain active measures to foster equ
The question of international peace and security today includes far more than merely weapons and balance of power. The cold war conception of state security with primary focus on external aggression failed to offer adequate protection against the everyday threats facing the people of the world - threats that often are more tangible than a looming threat of war. Entrusted with the responsibility fo
