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In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

The Membership of the European Union, brings along guidelines for national tax provisions, securing the freedoms of movement which exists within the European Community. It is above all the four fundamental freedoms of the EC Treaty, the freedom of movement of goods, service, capital and labour which aim to secure removal of obstacles and safeguard the free movement within the inner market of the C

Across a wide range of cultural and socio-political contexts, matchmaking has been valued as a legitimate profession that involves labor and remuneration in cultures. It represents the long-lasting commercialization of effective intimacy building. In the era of algorithms and platforms,the emergence of modern matchmaking, such as in mobile dating apps (MDAs), showcases the impact of platformizatio

The clinical utility of microfluidic techniques is often hampered by an unsatisfying sample throughput. Here, the effect of inertial forces on acoustofluidic particle sorting at high sample throughputs is investigated experimentally and theoretically. Polystyrene particles are acoustically prefocused to obtain precise trajectories. At increased flow rates it is observed that the particle stream is

Owing to recent developments in CMOS technology, it is now possible to exploit tomographic microscopy at third-generation synchrotron facilities with unprecedented speeds. Despite this rapid technical progress, one crucial limitation for the investigation of realistic dynamic systems has remained: A generally short total acquisition time at high frame rates due to the limited internal memory of av

Samråd är ett obligatoriskt moment i den svenska samhällsplaneringen i dag. Samtidigt visar forskning att det lagstadgade samrådet inte är tillräckligt för att skapa ett medborgardeltagande som har inflytande och är representativt. Uppsatsen har studerat metoder för medborgardialog i Stockholms stads projekt Fokus Skärholmen. Eftersom Fokus Skärholmen är ett pilotprojekt för socialt hållbar stadsuConsultation is a mandatory element in Swedish community planning today. At the same time, research shows that the statutory consultation is not sufficient to create a civic participation that is influential and representative. The thesis has studied methods for citizen dialogue in the City of Stockholm's project Fokus Skärholmen. Since Fokus Skärholmen is a pilot project for socially sustaina

Purpose: The purpose of this study is to contribute to an expansion of what can be considered as a brand. Specifically, this paper examines how streaming series can be seen as brands through a brand identity lens. Methodology: A qualitative research approach, with a social constructivist perspective, has been done by applying the Brand Identity Prism, with the additional element brand promise, to

This essay is based on an observation, made by the author, that the scenes in Malmö for rap battles and roast battles have actors in common. To identify and discuss why that is, the essay will conduct an aesthetic analysis and compare common tools used by rappers and comedians in the respective scenes. The analysis relies on discussions and theories about music as a performance and the term “music

Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu

In the offshore industry, reliability of installed equipment is of paramount concern due to safety, environmental and economic consequences. The costs of unplanned shutdowns and maintenance have high economic implications and are of increasing importance with tighter profit margins. Reliability is therefore of significance when selecting equipment model and brand. This report presents a survey of

Healthy eye lenses are transparent and flexible, able to adapt shape in order to focus on far away and close-by objects. With age, however, this flexibility is lost, leading to a condition known as presbyopia. This vision disorder where close-by objects appear blurred commonly starts around the age of 40. The aim of this thesis is to elucidate the molecular origin of the gradual hardening of the c

Throughout five chapters, the thesis deals with the issues of international humanitarian and human rights law arising out of the practice of punitive house demolition, that is repetitively utilized in the Occupied Palestinian Territories by the Israeli authorities, in response to the acts of insurgency/terrorism. The first chapter (Introduction) enables the reader to get a glimpse of the precise o

Background: Older adults spend more time at home after retirement, and the home becomes a central place for activity. While research indicates that indoor lighting, exposure to daylight, physical activity and sleep interact to influence functioning, mood and daily rhythm, strategies are needed to promote behavioural changes to optimise these factors in daily life. The objective is to design an int