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Background: Studies on national policies for biologics are warranted. Objectives: To map and compare national healthcare set-ups for prescription, start, switch, tapering, and discontinuation of biologic/targeted synthetic disease-modifying antirheumatic drugs (DMARDs) in patients with psoriatic arthritis and axial spondyloarthritis across Europe, and assess the healthcare set-ups in relation to c
Background: Postmastectomy radiotherapy (PMRT) impairs the outcome of immediate breast reconstruction in patients with breast cancer, and the sentinel lymph node (SLN) status is crucial in evaluating the need for PMRT. The aim of this study was to develop and validate models to stratify the risk of clinically significant SLN macrometastases (macro-SLNMs) before surgery. Methods: Women diagnosed wi
Most agricultural and food policies often overlook diversity of farming households, resulting in generalized and ineffective interventions. Recognizing changing and diverse characteristics of farm types is therefore critical. Using data from 502 households in West Pokot County, Kenya, we employ principal component and cluster analyses to create farm typologies to guide targeted policy intervention
This study analyses the performance of the satellite derived Plant Phenology Index (PPI) against the Normalized Difference Vegetation Index (NDVI) for estimating start of season (SOS) and end of season (EOS) of vegetation growth in part of the Balkan Peninsula, Southeastern Europe (2000 – 2016). Results revealed that PPI and NDVI differ considerably; SOS and EOS may diverge by more than one month
In modern history, Sweden has experienced two major financial crises: the early 1990s and the global financial crisis in 2008. During the last decades, there has been an increased global focus on regulating and supervising banks, where Basel III is the leading framework. Today, one of the most debated issues within the global economy is Covid-19. It is uncertain how the pandemic will affect countr
Purpose: In 2019 Varian EthosTM linear accelerator (Varian Medical Systems, CA, USA) with integrated artificial intelligence (AI) was installed at Herlev Hospital, Copenhagen, Denmark, enabling online adaptive radiotherapy (oART) e.g for bladder cancer patients with a large margin reduction. The AI utilizes so called influencers for initial delineation of the targets and organs at risks (OAR) usin
Old age is something that affects everyone, sooner or later and in different ways. The question on how to take care of older persons and support them when getting older might be more relevant now than ever, as the population over 60 years old is expected to grow with 40 percent in the coming 10 years. In an older human being, every age is preserved. In an 80-year-old mind there might live a little
Less than a decade ago, Swedish law demanded that a person who wanted to change their legal gender had to be without any ability to reproduce. This demand led to many trans people being forcibly sterilized. Even though the demand is now removed from law, lingering effects continues to affect trans people in their reproductive journey. This study examines barriers faced by trans people in three sta
The research on digitalisation has experienced a shift in the last decade, and animportant facilitator of the effects of business World digitalisation is the increased use of mobile devices. Furthermore, research on value creation has also gone through changes recently. Although much value research has been conducted, there is a gap in retail digitalisation research and the consumers’ interaction
A large pulse of atmospheric Cl-36 generated by a limited number of nuclear tests peaked in the late 1950s to early 1960s. The corresponding enhanced Cl-36 deposition is seen in various glaciological archives in the Northern Hemisphere. The profile of the bomb spike recorded in firn layers at Vostok Station, central East Antarctica. has been measured by employing accelerator mass spectrometry (AMS
Purpose. To define the association between venous volume as measured with air-plethysmography and the duplex ultrasound measured diameter of incompetent perforator of the lower limb. Patients and methods. Thirty-six patients with chronic venous disease were investigated with air-plethysmography and duplex ultrasound. Venous volume and venous filling time was measured. Venous filling index was calc
Lifetime tests of solar reflector materials are eligible prior to application, to prove the stability of the optical properties. In this work, six reflector materials were aged outdoors and in a climatic test chamber. The surfaces of the samples were inspected using profilometry and optical microscopy. The total and specular reflectance spectra were measured using spectrophotometry and the weighte
Popular Abstract in Swedish Avhandlingen behandlar kapacitet i cirkulationsplatser. Kapaciteten för ett körfält i en tillfart kan beräknas med teorin för kritiska tidsavstånd. Denna bygger på interaktioner mellan fordon med företräde (överordnade fordon) och fordon som skall lämna företräde (underordnade fordon). Det kritiska tidsavståndet är det minsta tidsavstånd mellan två överordnade fordon soProblem: The thesis deals with the capacity of two-lane roundabouts and with vehicle-vehicle interactions there. Method: The interactions and the corresponding capacity are modelled by gap-acceptance theory. Various components of this theory are discussed, models for headways in the multi-lane case and for the estimation of critical gaps for the two major streams being developed and being applied
Conclusions. Preoperative gentamicin in combination with vestibular 'prehab' offers a possibility to reduce postoperative malaise and speed up recovery and may be used for patients undergoing such surgery when there is remaining vestibular function. Objectives. Removal of pontine angle tumours in a patient with remaining vestibular function causes symptoms of acute vestibular loss. A simultaneous
Popular Abstract in Swedish Förbättrad patientsäkerhet och omvårdnad av patienter med höftraktur Intervention granskad i det nationella kvalitetsregistret RIKSHÖFT Varje år drabbas ca 18 000 personer i Sverige av höftfraktur efter fall. Höftfraktur är ett samlingsnamn för två frakturtyper i den övre delen av lårbenet. Den ena frakturtypen är lokaliserad till lårbenshalsen (cervikal fraktur) och dAim: Hip fractures are common and costly. The overall aim of this thesis was to explore how different clinical pathways influence safety and quality of care among patients with a hip fracture and to test the usefulness of the national quality register RIKSHÖFT as a working tool. The aim in paper I was to improve the outcome of patients with a hip fracture through optimized preoperative pain relief
PURPOSE: To evaluate the effects on cost, and number of primary and supplementary neuroradiologic examinations, after introducing MR imaging as the primary modality in the evaluation of the lumbar spine. MATERIAL AND METHODS: Two 5-month periods were compared: period 1--before MR; and period 2--after introduction of a 2nd MR device. In period 1, patients were examined with myelography and/or CT af
In the water-oxidizing reactions of photosystem II (PSII), a tyrosine residue plays a key part as an intermediate electron-transfer reactant between the primary donor chlorophylls (the pigment P-680) and the water-oxidizing Mn cluster. The tyrosine is deprotonated upon oxidation, and the coupling between the proton reaction and electron transfer is of great mechanistic importance for the understan
We investigated whether dorsal hindbrain and/or peripheral cocaine- and amphetamine-regulated transcript peptide (CARTp) acts to suppress gastric emptying of a caloric stimulus. Furthermore, effects of dorsal hindbrain CARTp on sucrose consumption and licking microstructure was studied, as well as the possible contribution of corticotropin-releasing factor (CRF) receptors to mediate effects of CAR
