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Purpose: The purpose of this study is to investigate the effects of film holes’ arrangements and jet Reynolds number on flow structure and heat transfer characteristics of jet impingement conjugated with film cooling in a semicylinder double wall channel. Design/methodology/approach: Numerical simulations are used in this research. Streamlines on different sections, skin-friction lines, velocity,
Purpose: Endwall film cooling protects vane endwall by coolant coverage, especially at the leading edge (LE) region and vane-pressure side (PS) junction region. Strong flow impingement and complex vortexaa structures on the vane endwall cause difficulties for coolant flows to cover properly. This work aims at a full-scale arrangement of film cooling holes on the endwall which improves coolant effi
OBJECTIVE: The microenvironment of colon cancer (CC) is heterogeneous including cells of myeloid lineage affecting tumor growth and metastasis. Two functional subtypes of myeloid cells have been identified; one (M1) is tumor-inhibitory and the other one (M2) is tumor-promoting. Whether the three myeloid markers EMR1, CD206 and CD86 are expressed only in the infiltrating myeloid cells or also in th
Forensic psychiatric patients constitute a heterogeneous patient group, with common comorbidity within the externalizing spectrum. Increased knowledge on early antecedents in the pathway to severe mental illness and criminality is needed. In this study, we investigated early onset externalizing behaviors in three groups of forensic psychiatric patients 1) patients without contact with child and ad
Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stress and emotional states in caregivers. We here report mitochondrial RC activities, mitochondrial DNA copy number (mtDNAcn), and the composite MHI in unmedicated and
BACKGROUND: The frequency of central venous catheter (CVC) related complications in hematological patients has previously been studied but some uncertainty remains. Therefore, this observational cohort study was designed primarily to investigate mechanical and infectious complications related to CVC insertion in hematological patients and secondarily, to identify factors associated with these comp
BACKGROUND: Heparin-binding protein (HBP) is a neutrophil-derived pro-inflammatory protein, an inducer of endothelial dysfunction and vascular permeability and a promising prognostic biomarker in sepsis. This exploratory study aims to describe the kinetics of plasma HBP during septic shock and investigate an association between repeated measures of HBP concentration and cardiovascular organ dysfun
Kursbok om Alternativ och Kompletterande Kommunikation (AKK), med fokus på kommunikationshjälpmedel, praktiska metoder och förhållningssätt. Boken ingår i ett kursmaterial i tre delar, för utbildning av personliga assistenter och andra som arbetar och lever nära ungdomar och vuxna med omfattande kommunikationssvårigheter på grund av funktionsnedsättning.
Laser-induced fluorescence for remote imaging of historical monuments is an established technique, which in this work has been used in measurement campaigns at the Coliseum and the Baptistery of San Giovanni in Laterano in Rome, Italy. The results presented here are examples that show that biodeteriogens can be monitored and that. materials can be identified. Also, cleaned and soiled areas on the
Physicochemical properties of solutions of charged colloids are often dominated by the electrostatic interactions present in such systems. A full determination of these properties constitutes a highly nontrivial many-body problem involving long-range interactions. In electrostatically strongly coupled systems, it is essential to explicitly include both the charged colloids and the small ions in th
The measurement of potential enzymatic activities has been proposed as an efficient method to infer nutrient limitations for microorganisms in environmental samples. To validate this use, confirmation with direct methods of microbial growth responses to resource additions are required. We experimentally manipulated nutrient-poor soils from the afromontane subtropics with relatively low (grassland
The COVID-19 pandemic and its impact on society has been suspected to affect gambling behaviors. Potentially, the pandemic crisis may result in increased problem gambling, for example, due to COVID-19-related psychological distress, unemployment, and financial difficulties. In ad-dition, the cancellation of sports in early parts of the crisis has been suspected to alter gambling behaviors. Policy
Target Temperature Management (TTM) is standard care following out of hospital cardiac arrest (OHCA). The aim of the study was to evaluate if treatment temperature (33°C or 36°C) or other predefined variables were associated with the occurrence of bleeding in the TTM study. This study is a predefined, post hoc analysis of the TTM trial, a multinational randomized controlled trial comparing treatme
Numerous recent studies project that ‘climate engineering’ technologies might need to play a major role in the future. Such technologies may carry major risks for developing countries that are often especially vulnerable to, and lack adaptive capacity to deal with, the impacts of such new technologies. In this situation, one would expect that developing countries—especially the least developed cou
Purpose: To provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of the condition in the Western world. Methods: Non-systematic focused literature review. Results: Sickle retinopathy results from aggregation of abnormal hemoglobin
Popular Abstract in Swedish Vårt immunförsvar måste ständigt vara redo att försvara oss mot angrepp utifrån. Det måste kunna agera selektivt för att skydda oss mot främmande mikroorganismer som virus och bakterier. Om immunförsvaret istället missbedömer kroppens egna celler för att vara inkräktare och attackerar dessa, inträffar det vi kallar autoimmunitet. De autoimmuna sjukdomarna har ökat överaAim: The general objective of the present research was to study the association between type 1 diabetes and celiac disease, and the effects of dietary gluten on the risk of developing type 1 diabetes. More specific aims were as follows: to estimate the prevalence of celiac-disease-associated autoantibodies in children with type 1 diabetes; to study the connection between non-HLA genetic risk marke
Statement of Purpose: Chronic lung diseases are one of the major health problems that cause death and disability. Approximately 65 million people suffer from chronic lung diseases, and the number of patients is predicted to increase worldwide 1
