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Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids ARTICLE Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids Alessandro Fiorenzano 1✉, Edoardo Sozzi 1, Marcella Birtele 1, Janko Kajtez 1, Jessica Giacomoni 1, Fredrik Nilsson 1, Andreas Bruzelius 2, Yo
Since EU’s expansion to incorporate former Communist countries, attempts to solve the so-called “Roma issue” spurred an unprecedented array of policies, interventions and measures at national and transnational level. Instead of the expected positive changes, discrimination and poverty worsened. The current migration waves, economic crisis, and the surge of far-right nationalism, contributed to an
I Sverige finns ett antal företag som med stöd av offentlighetsprincipen samlar in personuppgifter ur allmänna handlingar och publicerar dessa i söktjänster på internet. Genom användning av söktjänsterna går det att skapa sig en utförlig bild av en viss individ. Söktjänsterna har i regel beviljats utgivningsbevis och omfattas därför av grundlagsskyddet i YGL. I Sverige har en vedertagen uppfattninIn Sweden, there are several companies that, relying on the principle of public access to official documents, gather personal data and publish this information in online search services. Through use of these services, it is possible to access a detailed profile of a specific individual. The search services have generally been granted a so-called certificate of publication and are consequently prot
In 2008, the National Library of Sweden decided to transition from the Swedish system of classification, SAB, to the internationally established system Dewey Decimal Classification (DDC). The aim of this master’s thesis is to study the process of transition and the effect of this transition on the library collections and users of three Swedish libraries: two university libraries and one public lib
Världen förändras kontinuerligt. Företag arbetar idag hårt för att hålla jämna steg med omvärlden för att på så vis hålla sig konkurrenskraftiga. Att arbeta för att hitta nya affärsmöjligheter har blivit av allt större betydelse. IKEA är ett globalt företag som står inför en enorm tillväxt för att nå deras mål till år 2020. För att klara denna tillväxt och för att kunna säkra försörjningen till nyThe world is continuously changing. Today many companies work hard to keep up with the surrounding world to stay competitive. To work with finding new business opportunities has become of higher importance than ever. IKEA is a global company facing a tremendous growth to reach their goal for 2020. To manage this growth and be able to secure supply to new retail markets, the company needs to increa
Since 2011, LUNARC has aimed to provide an interactive HPC environment for its resource users. Several different architectures have been used, but since 2013, we have been using a remote desktop environment based on Cendio's ThinLinc [1] combined with a custom backend framework, GfxLauncher [2], supporting hardware-accelerated graphics applications and Jupyter Notebooks [3] submitted to the backen
Japan's January withdrawal of funding from the UN Committee on the Elimination of Discrimination against Women highlights its aversion to addressing gender equality issues at home. Despite externally presenting a commitment to progressive gender norms, a tension between Japan's international image and its domestic reality persists. Japan continues to rank low in major gender equality indexes as re
The aim of this study was to describe the extent to which men in psychiatric care have experienced emotional, physical, and sexual abuse during the life course and the association between this experience and being a perpetrator oneself. The aim was also to identify who exposed them to abuse and whether there was an association between the category of abuser and being a perpetrator oneself. A cross
BackgroundEndostatin is a promising biomarker for predicting acute kidney injury (AKI) and mortality in the intensive care unit (ICU). We investigated plasma endostatin levels at ICU admission as predictors of new-onset AKI within 48 h after ICU admission, renal replacement therapy (RRT) within 7 days after ICU admission, and 30-day mortality.MethodsA retrospective multicentre study was performed
Introduction: Psychological pain is a central risk factor for suicidal behaviour. Nonverbal synchrony between patients and therapists has been shown to facilitate the development of therapeutic alliance, which in turn is linked to symptom reduction. Building on these associations, the present study investigated whether movement synchrony in suicide-specific therapy exceeds random synchrony and whe
Background: Ambulatory oxygen therapy is prescribed for patients with chronic lung diseases who experience exertional hypoxemia. However, available devices may not adequately meet user requirements, and their performance characteristics are heterogeneous. Objective: This study aims to identify devices available for delivery of ambulatory oxygen therapy, the technologies that they use to generate o
Additive manufacturing (AM) makes it feasible to realise complex lattice structuresthat provide structural flexibility through engineered structural design rather thanrelying solely on material softness. Across sectors such as furniture, healthcare,protective equipment, and robotics, such flexibility is a core functional requirement,that influences comfort, fit, impact response, lightweighting, an
Attention Restoration Theory point to nature as a particularly good candidate for restoring the ability to focus and inhibit distractions. However, little effort has been directed to elaborating on what makes nature's visual pattern unique for restoration purposes. One suggested explanation is the fractal properties of natural patterns (Hagerhall, 2005). Both perception studies (Hagerhall et al.,
