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HbA1C is the stable glucose adduct to the N-terminal group of the beta-chain of HbA0. The measurement of HbA1c in human blood is most important for the long-term control of the glycaemic state in diabetic patients. Because there was no internationally agreed reference method the IFCC Working Group on HbA1c Standardization developed a reference method which is here described. In a first step haemog
The oscillations between glacial and interglacial climate conditions over the past three million years have been characterized by a transfer of immense amounts of water between two of its largest reservoirs on Earth - the ice sheets and the oceans. Since the latest of these oscillations, the Last Glacial Maximum (between about 30,000 and 19,000 years ago), similar to50 million cubic kilometres of
Short-hairpin RNA (shRNA)-mediated gene knockdown is a powerful tool for targeted gene silencing and an emerging novel therapeutic strategy. Recent publications, however, reported unexpected toxicity after utilizing viral-mediated shRNA knockdown in vivo. Thus, it is currently unclear whether shRNA-mediated knockdown strategy can be used as a safe and efficient tool for gene silencing. In this stu
The radiation and total efficiencies, the amount of gas radiation from vapour and carbon dioxide and contribution from convective heat transfer for different operating conditions have been measured and modelled in an industrial gas heated IR dryer. Instrumentation to facilitate the measurement of the spectral distribution of the radiation heat fluxes in industrial infrared equipment has been devel
Prepared under the framework of the European Cluster Alliance (ECA), the report provides an overview of existing good practice examples of different tools and analytical methods used during the cluster-making process. The report is based on the results of an international survey of experts working in the field, and the outcomes of a workshop organised in Copenhagen in September 2008. A number of
The 2008–2009 global financial crisis triggered ‘Green Energy Economy’ (GEE) policy packages to stimulate green growth in many countries. China soon became a leader and, supported by its 11th Five-Year Plan (2006–2010), devoted approximately one-third of its US$ 647 billion stimulus package to green energy technologies. Since then, numerous policy instruments have been implemented to encourage ‘Gr
The performance of an iris recognition system depends greatly on how well the iris segmentation part of the system performs its task. The performance of an iris segmenta- tion algorithm can be evaluated using different criteria and methods. Some of the methods evaluate the performance of the segmentation algorithm based on the performance of the whole iris recognition system. Other methods evaluat
When adapting environments for the physically disabled, it is important to encourage and activate not only the person concerned, but also other people involved or affected. A computer aided planning tool has been developed to support the participation of all persons involved, as well as supporting the planner’s (e.g. an occupational therapist) design of the environment. The prototype development a
In this paper we prove threshold saturation for spatially coupled turbo codes (SC-TCs) and braided convolutional codes (BCCs) over the binary erasure channel. We introduce a compact graph representation for the ensembles of SC-TC and BCC codes which simplifies their description and the analysis of the message passing decoding. We demonstrate that by few assumptions in the ensembles of these codes,
To fulfill increasing requirements within the manufacturing sector, highly flexible and adaptable automation systems are needed. It is desirable to have one integrated approach that stretches from the process planning phase, through the implementation phase and all the way to the phase for execution of the process control logics. One promising approach is to use the concepts of service-oriented ar
Theoretical considerations of eye design allow us to find routes along which the optical structures of eyes may have evolved. If selection constantly favours an increase in the amount of detectable spatial information, a light-sensitive patch will gradually turn into a focused lens eye through continuous small improvements of design. An upper limit for the number of generations required for the co
The monotone rearrrangement algorithm was introduced by Hardy, Littlewood and Po ́lya as a sorting device for functions. As- suming that x is a monotone function and that an estimate xn of x is given, consider the monotone rearrangement xˆn of xn. This new estimator is shown to be uniformly consistent. Under suitable as- sumptions, pointwise limit distribution results for xˆn are obtained. The fra
