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The European League Against Rheumatism recommendations for the management of antineutrophil cytoplasmic antibody-associated vasculitis have been recently published. Unique to recommendation development, they were also voted on by members of a learned society. This paper explores the wider validity of the recommendations among people who self-identify as clinicians caring for patients with vasculit
Many natural and industrial proteins are known to have properties that can result in type I hypersensitivity, however, to date, no validated test system exists that can predict the sensitizing potential of these allergens. Thus, the objective of this study was to develop a protocol based on the myeloid cell-based Genomic Allergen Rapid Detection (GARD) assay that can be used to assess and predict
Background: The Activity Rating Scale (ARS) for disorders of the knee evaluates the level of activity by the frequency of participation in 4 separate activities with high demands on knee function, with a score ranging from 0 (none) to 16 (pivoting activities 4 times/wk). Purpose: To translate and cross-culturally adapt the ARS into Swedish and to assess measurement properties of the Swedish versio
This paper discusses social science education in four Swedish upper secondary schools as conceptualized – by teachers and students – and as carried out in the classroom. More specifically, it addresses education on migration, public international law and human rights in a classroom where about a third of the students have immigrant background. Analysing data collected through classroom observation
A new carbon isotope record with conodont biostratigraphy is presented for the entire Early Triassic from the Musandam Peninsula, United Arab Emirates (UAE). This is a near-continuous and exclusively shallow marine carbonate succession that allows analysis of a high-resolution primary carbon cycling signature in the absence of significant depth-dependent or lithologic controls. The Musandam carbon
Despite the initial promise of immunotherapy for CNS disease, multiple recent clinical trials have failed. This may be due in part to characteristically low penetration of antibodies to cerebrospinal fluid (CSF) and brain parenchyma, resulting in poor target engagement. We here utilized transcranial macroscopic imaging to noninvasively evaluate in vivo delivery pathways of CSF fluorescent tracers.
The two lowest potential energy surfaces for C(3P)+NO(2Π) have been investigated. The stationary points were first located using CASSCF gradient calculations and the geometries reoptimized using complete active space second-order perturbation theory. Zero-point corrections have been included in the energetics. In addition to the three linear conformations CNO, NCO and CON, a previously unreported
Donald Trump’s decision to recognise Jerusalem as the capital of Israel, and start preparations for the US to move its embassy from Tel Aviv to the contested city, has the potential to further inflame tensions across the Middle East.
A search for the narrow structure, X(5568), reported by the D0 Collaboration in the decay sequence X→Bs0π±, Bs0→J/ψφ, is presented. The analysis is based on a data sample recorded with the ATLAS detector at the LHC corresponding to 4.9 fb-1 of pp collisions at 7 TeV and 19.5 fb-1 at 8 TeV. No significant signal was found. Upper limits on the number of signal events, with properties corresponding t
Solar modulated variations in cosmogenic radionuclide production provide both information on past changes in the activity of the Sun and a global synchronization tool. However, to date the use of cosmogenic radionuclides for these applications is almost exclusively based on 10Be records from ice cores and 14C time-series from tree rings, all including archive-specific limitations. We present the f
In this article, we briefly identify three main challenges/issues that should be taken into consideration in the institutionalization of entrepreneurship research: (1) recognizing the complexity of the phenomenon under study; (2) producing interesting, relevant and useful research results for all stakeholders; and (3) developing a critical posture in research. Following the discussion of these cha
Xylooligosaccharides (XOS) have gained increased interest as prebiotics during the last years. XOS and arabinoxylooligosaccharides (AXOS) can be produced from major fractions of biomass including agricultural by-products and other low cost raw materials. Endo-xylanases are key enzymes for the production of (A)XOS from xylan. As the xylan structure is broadly diverse due to different substitutions,
