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Treatment with anti-CD20 antibodies is only moderately efficient in chronic lymphocytic leukemia (CLL), a feature which has been explained by the inherently low CD20 expression in CLL. It has been shown that CD20 is epigenetically regulated and that histone deacetylase inhibitors (HDACis) can increase CD20 expression in vitro in CLL. To assess whether HDACis can upregulate CD20 also in vivo in CLL

Earlier studies have shown that while free-viewing images people tend to gaze at regions with a high local density of bottom up features such as contrast and edge density. In particular, this tendency seems to be more emphasized during the first few fixations after image onset. In this paper, we present a new method to investigate how gaze locations are chosen by introducing varying image resoluti

This study investigates online material published in reaction to a Science magazine report showing the absence of peer-review and editorial processes in a set of fee-charging open access journals in Biology. Quantitative and qualitative textual analyses are combined to map conceptual relations in these reactions; and to explore how understandings of scholarly communication and publishing relate to

The extent to which in-situ global mechanical tensioning (GMT) can be used to modify the residual stress state in friction stir (FS) welds is investigated in this article. Residual stress distributions have been determined by synchrotron X-ray and neutron diffraction for four sets of FS welds in high-strength AA7449-W51 and lithium containing AA2199-T8 aerospace aluminum alloys subjected to a syst

The proposed algorithm aims at helping diabetic patients which use multi-dose injection (MDI) therapy to determine the dose and time of insulin and glucose intakes to stabilize their blood glucose (BG) concentration. The objective is to spend most of the time in normal BG range (70-180 mg/dl). The control was done by minimizing the risk of hypo- and hyperglycemia over the doses and times of insuli

In this article we take the classic meaning of exemplum as a point of departure to show how examples are marked and used in oral discourse on 'others'. The empirical material is a transcribed focus group interview with Swedish students talking about a trip to Warsaw. Examples may be marked in explicit ways but also in implicit ways. Some examples seem recognizable by their allusive nature, others

Many scholars and philosophers inspired by Antiquity, have commented upon a transformation of lived religion and a changing picture and technology of the Self during Late Antiquity. The Nag Hammadi Library contains a diverse body of thought and it is here argued that these texts are found in the epicentre of Late Antique conversion of religion and Self, containing important illustrations of new em

The mechanism of atomic and molecular ionization in intense, ultra-short laser fields is a subject which continues to receive considerable attention. An inherent difficulty with techniques involving the tight focus of a laser beam is the continuous distribution of intensities contained within the focus, which can vary over several orders of magnitude. The present study adopts time of flight mass s

The objective of this study was to describe environmental barriers and investigate the nature of accessibility problems in housing among single-living, very old people (N = 1,150) in urban regions in three European countries (Sweden, Germany, Latvia), in a one-year perspective. A specific feature of this study is the explicit conceptual differentiation between environmental barriers and accessibil

This paper presents a practical risk analysis method for critical, large-scale IT systems in an organisation. The method is based on reliability block diagram modelling and was adapted to fit the requirements of governmental organisations and to reduce the effort required to capture complex failure behaviour. Through the use of different failure categories the risk analysis can be simplified, the

Inlåsta med avfall ...? HERVÉ CORVELLEC & ANETTE SVINGSTEDT | LUNDS UNIVERSITET EU har beslutat om en “avfallstrappa” – som handlar om att vi i första hand ska förebygga avfall. Går inte det är det återbruk som gäller, därefter återvinning av materialet. I sista hand bör avfallet eldas upp för energiåtervinning eller läggas på deponier. Men frågan är hur vi når till det högsta steget i avfallstrap

https://www.ses.lu.se/sites/ses.lu.se/files/corvellec_svingsted_nordh_inlasta_med_avfall_juni_2016_15_juni_sartryck_till_almedalen.pdf - 2026-05-11