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Lung cancer (LC) generally lacks unique core symptoms or signs. However, there are a multitude of bodily sensations that are often non-specific, not easily understood, and many times initially not recognized as indicative of LC by the affected person, which often leads to late diagnosis. In this international qualitative study, we inductively analyzed retrospective accounts of 61 people diagnosed
In this paper, I briefly present my doctoral thesis research proposal. Recognizing that information has long been an important asset for any organization, I wish to explore in depth the management and use of information in contemporary information-intensive organizations such as academic libraries. Additionally, this research proposal emerges out of recognition that the academic library is a dynam
Objectives Nocturnal hypoxia in obstructive sleep apnoea (OSA) is a potential risk factor for cancer. We aimed to investigate the association between OSA measures and cancer prevalence in a large national patient cohort. Design Cross-sectional study. Settings 44 sleep centres in Sweden. Participants 62 811 patients from the Swedish registry for positive airway pressure (PAP) treatment in OSA, link
BACKGROUND: Patients with chronic respiratory failure treated with long-term oxygen therapy (LTOT) often have severe breathlessness, impaired exercise performance, and high but variable mortality that is difficult to predict. We aimed to evaluate breathlessness and exercise performance upon starting LTOT as predictors of overall and short-term mortality.METHODS: This was a longitudinal, population
Breathlessness is a centrally processed symptom, as evidenced by activation of distinct brain regions such as the insular cortex and amygdala, during the anticipation and/or perception of breathlessness. Inhaled L-menthol or blowing cool air to the face/nose, both selective trigeminal nerve (TGN) stimulants, relieve breathlessness without concurrent improvements in physiological outcomes (e.g., br
Background Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET. Methods A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory
Since the 1980’s, additive manufacturing (AM) has gradually advanced from rapid prototyping applications towards fabricating end consumer products. Many small companies may prefer accessing AM technologies through service providers offering production services as result-oriented Industrial Product-Service System (IPSS) rather than investing in their own production line. This study investigated pot
Aim: The primary objective of this study was to describe demographics and end-of-life treatments of children with cancer at a government tertiary cancer center in India. Methods: A retrospective review was undertaken of medical charts of all children younger than 18 years, who died as inpatients while undergoing treatment at the pediatric oncology department between April and September 2016. Data
Quantitative evaluations are valuable in the strive for improvements and asserting quality. However, the field of Command & Control (C2) evaluations are hard to navigate, and it is difficult to find the correct measurement for a specific situation. A comprehensive Scoping Study was made concerning measurements of C2 performance and effectiveness. A lack of an existing appropriate framework for
A comparative experimental investigation has been performed, comparing the emissions from a synthetic jet fuel and from Jet AI. In the investigation, the unburned hydrocarbons were analyzed chemically and the regulated emissions of NOX, CO and HC were measured. All combustion tests were performed under elevated pressures in a gas turbine combustor rig. A Swedish company, Oroboros AB, has developed
Treatment with anti-CD20 antibodies is only moderately efficient in chronic lymphocytic leukemia (CLL), a feature which has been explained by the inherently low CD20 expression in CLL. It has been shown that CD20 is epigenetically regulated and that histone deacetylase inhibitors (HDACis) can increase CD20 expression in vitro in CLL. To assess whether HDACis can upregulate CD20 also in vivo in CLL
This paper presents a practical risk analysis method for critical, large-scale IT systems in an organisation. The method is based on reliability block diagram modelling and was adapted to fit the requirements of governmental organisations and to reduce the effort required to capture complex failure behaviour. Through the use of different failure categories the risk analysis can be simplified, the
Popular Abstract in Swedish Nanotekniken håller i skrivande stund på att revolutionera samhället med nya innovationer inom exempelvis elektronik och medicin. En viktig del i detta är utvecklingen av nya och förbättrade sätt att avbilda strukturer av nanometerstorlek (en nanometer är en miljarddels meter). Avancerade karakteriseringsmetoder skapar en ökad förståelse för hur nanostrukturer beter sigUltrafast nano-optics is a new and quickly evolving research field centred around the control, manipulation, and application of light on a nanometre and femtosecond scale. This can lead to improved electro-optical devices, more sensitive spectroscopy, and real-time control of chemical reactions. However, understanding the simultaneous nanometre and femtosecond evolution of nano-optical fields requ
