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Intrauterine growth retardation (IUGR) is associated with abnormal neuro-developmental outcome. Aortic blood flow velocity waveforms have been shown to predict fetal distress in IUGR. Fetal aortic blood flow velocity waveforms were correlated to neuro-developmental performance at 7 years of age. Results suggest that abnormal fetal aortic blood flow velocity waveforms are associated with neuro-deve
Background: The management of cancer-related pain relies on access to opioids. When regular opioids are not tolerated, or are insufficient, methadone is an affordable and effective analgesic. Aim: The aim of the project was to describe the pattern of use and clinical experience of methadone in pediatric cancer pain at a governmental cancer hospital in Hyderabad, one of the four Indian cancer cente
BACKGROUND: Integration of oncology and palliative care has been shown to increase quality of life in advanced disease. To meet the needs of the growing older population, integration of palliative care and geriatrics has been proposed but scarcely described.OBJECTIVES: The aim of this study was to integrate palliative care into geriatrics by a structured care guide, the Swedish Palliative Care Gui
OBJECTIVES: To compare somatic healthcare usage among older people with intellectual disabilities (ID) to that of their age-peers in the general population, taking into account health and demographic factors, and to identify predictors for somatic healthcare usage among older people with ID.PARTICIPANTS: Equally sized cohorts, one with people with ID and one referent cohort, one-to-one-matched by
Background: Current evidence suggests that use of intracoronary imaging during percutaneous coronary intervention (PCI) of the left main coronary artery (LMCA) reduces mortality. However, there is a scarcity of data on the overall role of intracoronary imaging, particularly in other non-LMCA proximal coronary artery lesions. We aimed to investigate the association of use of intracoronary imaging o
Non-lethal infections are common in free-living animals and the associated sickness behaviours can impact crucial life-history trade-offs. However, little is known about the duration and extent of such sickness behaviours in free-living animals, and consequently how they affect life-history decisions. Here, free-living Eurasian blackbirds, Turdus merula, were immune-challenged with lipopolysacchar
Fibre-optic based sensing technologies are becoming popular in the field of geophysics since enable long range and high spatial resolution acoustic measurements. In this work, we present preliminary results obtained using quasi-distributed Fibre-Bragg grating sensing and Distributed Acoustic Sensing (DAS) to monitor seismic activities in an operational underground mine. 12 FBGs and 800 metres of f
Purpose: Getting an incurable oesophageal or gastric cancer diagnosis is a major stressful life event associated with severe physical, psychosocial and existential challenges. To provide timely and efficient support, based on patients' experiences, the aim of the study was to explore how patients newly diagnosed with incurable oesophageal and gastric cancer manage everyday life. Method: Semi-struc
Purpose: This study aimed to examine how young people living with Home Mechanical Ventilation experience the transition from childhood to young adulthood in relation to everyday life, perceived health and transition into adult professional healthcare. Methods: Nine young adults (three females and six males aged 18–31) were interviewed, and data was primary analysed using phenomenological hermeneut
Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor
False positive recall is a major issue in breast cancer screening and the introduction of artificial intelligence (AI) might affect which women who are unnecessarily recalled. We have investigated how an AI system works on false positive recalls at screening and compared with radiologist findings. Two-view digital mammography (DM) examinations from 656 recalled women (136 with screening detected c
Popular Abstract in Swedish Sotpartiklar i atmosfären är en del av klimatfrågan som är i särskilt stort behov av utredning. Dessutom har det visat sig, att samma partiklar orsakar mycket stora hälsoproblem; globalt, på Europeisk nivå, och till och med i förhållandevis förskonade länder som Sverige. Vi vet nu nästintill helt säkert att mänsklig påverkan leder oss in i ett varmare klimat. Vi behöveAerosol particles contribute significantly to the global burden of disease, and remain the main source of uncertainty in assessments of human-induced climate change. The microphysical characterization of particles is necessary to understand the roles they play in the detrimental effects of air pollution on human health, and in the energy budget of our planet. Soot particles are especially relevant
A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A constructi
Nanotechnology is an evolving scientific field that has allowed the manufacturing of materials with novel physicochemical and biological properties, offering a wide spectrum of potential applications. Properties of nanoparticles that contribute to their usefulness include their markedly increased surface area in relation to mass, surface reactivity and insolubility, ability to agglomerate or chang
This booklet is a report for a case study visit during four day field trip, a group of nine PhD students and their supervisors – all part of the National Research School for Architecture and Planning in the Urban Landscape, APULA – set out to explore what may be considered the outback of Western Europe’s conurbations, the transnational region of Kiruna -Narvik.Both “remote” and “resourceful”, “thr
Based on a new Swedish legislation for accident prevention and protection the support of the establishment of municipality accident prevention programs with documented basic data sets for decision-making is discussed. A division into four documents of basic data sets is proposed. A process is projected for the production, decree and compliment of municipal accident prevention programmes and the do
Antibody microarray is a novel technology with great promise within proteomics. Intense work is under way to evolve this methodology into the high-throughput proteomic research tool needed by the research community. Despite recent advances, there is a growing need for additional highperformance substrates for antibody microarrays as well as for protein arrays in general. In this study, we have suc
