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Lipid membrane and lipopolysaccharide (LPS) interactions were investigated for a series of amphiphilic and cationic peptides derived from human heparin cofactor II (HCII), using dual polarization interferometry, ellipsometry, circular dichroism (CD), cryoTEM, and z-potential measurements. Antimicrobial effects of these peptides were compared to their ability to disorder bacterial lipid membranes,

The immobilization of functional biomolecules to surfaces is a critical process for the development of biosensors for disease diagnostics. In this work we report the patterned attachment of single chain fragment variable (scFv) antibodies to the surface of metal oxides by the photodeprotection of self-assembled monolayers, using near-UV light. The photodeprotection step alters the functionality at

This work is aimed at presenting a design for the proposed HIBEAM beamline which seeks to perform neutron oscillation measurements at the European Spallation Source (ESS). The design is informed by beamline simulations performed with PHITS 3.33 and detector simulations performed with both PHITS and Geant4 11.2. The shielding, consisting of 45 cm of steel and 85 cm of heavy concrete at its thickest

Background: Parkinson’s disease (PD) is the second most common neurodegenerative disease, and it is linked with aggregation of α-synuclein protein. PD can be diagnosed using real-time quaking induced conversion (RT-QuIC) assay. RT-QuIC, despite its effectiveness, is not really understood in terms of the mechanisms driving it. Aim(s): The aim of the project was to reproduce RT-QuIC protocol develop

Let $\dim_H(\mathcal{J}_\epsilon)$ and $\dim_H(\mathcal{J}_{i\epsilon})$ denote the Hausdorff dimension of the Julia set of the polynomials $f_\epsilon(z) = z^2 -2 -\epsilon$ and $f_{i\epsilon}(z) = z^2 -2 +i\epsilon$ receptively for small $\epsilon>0$. This thesis contains two main Theorems, both dealing with the upper bound for the asymptotic behaviour of $\dim_H(\mathcal{J}_\epsilon)$ and $\dim

Abstract Purpose: This study investigates the impact of social influence on consumer preferences for product recommendations made by an AI or a human within the cosmetics industry, specifically in light of hedonic or utilitarian goals. Methodology: This quantitative research follows a deductive approach, using an online self-completion survey for data collection. A total of 659 valid responses w

Switzerland's current food system is unsustainable and responsible for 25% of the country's environmental footprint. Half of the greenhouse gas emissions from the Swiss food system are caused by meat and dairy consumption. Reducing Switzerland's GHG emissions from the food system requires an orchestrated approach, targeting amended consumption and production patterns. A primary change

Classical music institutions are confronting declining attendance among younger and diverse audiences, fearing an aging visitor demographic. The LUDICH Project at Lund University, in collaboration with several industry partners, academic institutions, the Malmö Symphony Orchestra and their home concert hall of Malmö Live aims to address this challenge by investigating innovative digital solutions

The consumption of plant-based, food alternatives is increasing globally. Yet, the digestion of plant proteins is hindered by various antinutritional and external factors. Therefore, delving into the extent of plant protein digestibility in the human body becomes essential, alongside efforts to enhance this process. The main aim of this present work was to determine the digestibility of plant-base

The unique perspective offered by unoccupied aerial systems (UASs) has great potential for enhancing emergency and disaster response (EDR). Through a scoping exercise of research around the use of UASs for situational awareness and interviews with practitioners, this paper assesses the current benefits offered by UASs for situational awareness in EDR and identifies and discusses four areas of cons

Based on the Spain’s annual and quarterly time series from 1980 to 2020, this paper presents the first case study on the dynamic effects of fiscal consolidation episodes on income distribution and the mechanisms driving the specific dynamics of the distribution. By estimating impulse response functions via Local Projections by Jordà (2005), I find supportive evidence of the increase in income ineq

The aim of this empirical study was to find out which characteristics, behaviors, and drives high-performing women have in common in order to illuminate why they have become successful in their work. The aim also included getting insights into some of the challenges that these women meet. Participants were fifteen high-performing women who work in business and academia in Sweden. Semi-structured,

This thesis discusses a rather contentious issue of how copyright law possesses musical works nowadays. It is essentially argued in the thesis that current copyright law appears to be too restrictive, leaving not enough space for creativity in the musical world. In this regard, the issue related to musical works are mainly analysed through the prism of the idea-expression dichotomy. One of the gen

In adaptive deep brain stimulation, a treatment for motor symptoms in Parkinson’s disease, the target of the stimulus is usually in the sub-thalamic nucleus or the globus pallidus. In this thesis, a new stimulus target called reticular thalamus is investigated in a rat model of Parkinson’s disease. The responses to the stimulus were recorded from both local field potentials and action potentials f

Streptomyces species are filamentous bacteria from the phylum Actinobacteria in which cell elongation occurs at the poles of the cell. This differs from many other bacteria like Escherichia coli where cell elongation occurs by insertion of peptidoglycan in the lateral wall. An essential protein for polar growth in Streptomyces is the coil-coiled protein DivIVA. DivIVA has an essential role in orch

Background/purpose Quantitative susceptibility mapping (QSM) is an MRI-based post processing technique to evaluate the magnetic susceptibility, χ, of human tissue using phase data. While brain imaging has been the most common application, other areas have also raised interest. For example, QSM of the articular cartilage of the knee has been suggested as a means to study the degeneration of this ti

In 2021, the Icelandic government stated that Iceland will implement an energy transition plan with the goal of becoming a 100% carbon neutral and fossil free nation by 2040, furthermore, that a doubling in renewable energy production was needed to reach that goal. This led to an upsurge of a discourse among stakeholders and concerned citizens about the future of Iceland. This thesis is an attempt

Populärvetenskaplig sammanfattning I dagens samhälle används diverse katalysatorer i många sammanhang för att påskynda kemiska reaktioner. Allt från produktion av ammoniak till rening av avgaser hjälps av olika katalysatorer. De katalysatorer som vi känner idag har tagits fram genom att testa olika materialkombinationer och utvecklingen har börjat stagnera. Enzymerna i våra kroppar är naturliga kA new instrument for near ambient x-ray photoelectron spectroscopy investigations of surfaces has been installed at beamline I511 of the MAX-II electron storage ring at the MAX IV Laboratory. This high pressure x-ray photoelectron spectroscopy instrument is capable of surface chemistry investigations in near ambient pressures using x-ray photoelectron spectroscopy (XPS), a technique that tradition