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The presence of different time scales in a dynamic model significantly hampers the efficiency of its simulation. In multibody systems the fact is particularly relevant, as the mentioned time scales may be very different, due for example to the coexistence of mechanical components controlled by electronic drive units, and may also appear in conjunction with significant nonlinearities. This paper pr
Alzheimer's Disease (AD) is the most prevalent form of dementia worldwide, yet the development of therapeutics has been hampered by the absence of suitable biomarkers to diagnose the disease in its early stages prior to the formation of amyloid plaques and the occurrence of irreversible neuronal damage. Since oligomeric A beta species have been implicated in the pathophysiology of AD, we reasoned
Objectives: We evaluated a method for gas monitoring in the mastoid cavity using tunable diode laser spectroscopy by comparing it to simultaneously obtained computed tomographic (CT) scans. Methods: The presented optical technique measures free gases, oxygen (O2), and water vapor (H2O) within human tissue by use of low-power diode lasers. Laser light was sent into the tip of the mastoid process
It is frequently observed that the local relative abundances of aquatic microbial taxa are correlated with their average relative abundance at the regional scale, which results in the composition of different communities being more similar than expected by chance or invariant. The degree to which communities within a region match the regional average community is variable and likely depends on sev
This thesis aimed to search for etiological clues about cancer of unknown primary(CUP) by gathering novel information. The Swedish national registries were used and CUP cases were identified according to the seventh revision of the International Classification of Diseases. A consistent increase before the late 1990s and a dramatic decrease afterwards were observed for CUP incidence among Swedes,re
In this paper we first critically review conventional environmental economics. We conclude that the standard theory offers too narrow a perspective for many real world problems and that many theories are not empirically tested. Consequently, environmental economics is at risk of producing aeroplanes without engines. Next, we welcome and discuss some recent trends, particularly the rapid developmen
The emergence of post-genomic approaches that couple chromatin immunoprecipitation (ChIP) assays to high-throughput technique has greatly advanced our ability to investigate epigenetic features associated with normal cell development and disease. Nevertheless, these techniques exhibit some limitations. Firstly, standard protocols usually require millions of cells, thus limiting their application t
Substituting Zn for Cu is known to rapidly quench superconductivity in the doped perovskites but the mechanism behind it is still not clearly understood. Single phase YBa2(Cu1-xZnx)(3)O7-delta (x=0.0 to 0.06) samples were synthesized and characterized using XRD, wet titration, resistivity, and ac susceptibility. Angle-integrated Valence Band Photo emission and Zn K-edge XAFS results clearly show t
We focus on exclusive production of neutral technipion (pi) over tilde (0) in pp collisions at the LHC, i.e. on pp -> pp (pi) over tilde (0) reaction. The dependence of the cross section on parameters of recently proposed vector-like Technicolor model is studied. Characteristic features of the differential distributions are discussed. For not too large technipion masses the diphoton decay channel
BACKGROUND: For a 1-day myocardial perfusion SPECT (MPS) the recommendations for administered activity stated in the EANM guidelines results in an effective dose of up to 16 mSv per patient. Recently, a gamma camera system, based on cadmium zinc telluride (CZT) technology, was introduced. This technique has the potential to reduce the effective dose and scan time compared to the conventional NaI g
The Cone Calorimeter test method has been one of the most used small-scale fire test method for years now and is at present widely spread over the world. In contrast to many other fire test methods, the Cone Calorimeter provides a range of data with sound scientific basis, which allows a wide range of applications. It can be used for modelling and also for enhanced product development. This paper
Objective. This study aimed to survey current Swedish practices for performing and handling transrectal ultrasound-guided prostate biopsies. Material and methods. A Swedish Urology Network (SUNe) was organized for the distribution of information, survey studies and research collaborations. A web-based questionnaire was distributed to the members in 2011. Results. In this first SUNe survey, 137 (91
Improving our knowledge of drivers’ behaviour, especially in hazardous situations is a key to understanding why accidents occur and how to improve safety on our roads. Crash surrogate measures have proven to be very useful in traffic safety analysis. As a valid crash surrogate measure shares the same logical chain of events as actual crashes, studying those events increases the opportunities to an
This longitudinal paper draws on data from a larger ongoing project and examines how students conceive of their opportunities to influence their study environment and how this may be related to their self-efficacy beliefs and their study motivation. Interpretative Phenomenological Analysis (IPA) was used to analyze semi-structured in-depth interviews of 10 students of a Masters Program in Engineer
We assessed the presence/absence and population size of a threatened beetle, Osmoderma eremita, inhabiting hollow oaks (Quercus robur). Population sizes varied widely between trees (10% of the hollow trees hosted two thirds of the individuals), and increased with the volume of wood mould (= loose material of dead wood) and the height of the entrances. Population density (number of adult beetles pe
As part of research into small group homes run by local authorities for those with severe mental illness the characteristics of the social environment was investigated. The ideal and real versions of the Community Oriented Program Environmental Scale (COPES) were administered to residents and staff of small group homes in a county in southern Sweden. Both these groups were also interviewed on thei
The maintenance of plumage color polymorphism in the parasitic jaeger (Stercorarius parasiticus) is still not well understood. Earlier studies indicated that selection may favor pale females and melanic males. If so, females would maximize their fitness, producing pale female and melanic male offspring. We therefore predicted that females might bias their offspring sex ratio toward daughters in pa
Participants in an international conference on the management of haemophilia patients with inhibitors developed a jointly authored summary of the findings and conclusions of the conference. Current knowledge of the genetic and immunologic mechanisms underlying inhibitor development was briefly summarized. Concerning the purported treatment-related risk factors, conference participants commented on
