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Aims:Research on the role of art in alleviating mental health problems has increased dramatically. However, it remains unclear whether mental health benefits of the arts are the same across different social contexts of arts participation. The aim of the study is to investigate associations between two modes of arts participation, solitary and group-based, and psychological wellbeing (12-item gener
Popular Abstract in Swedish Cystisk Fibros Cystisk Fibros (CF) är en relativt vanlig ärftlig sjukdom. Ungefär 1/37 personer i Sverige bär på anlag till CF, men bärare har inga symptom och vet därför inte att de har anlagen. För att få sjukdomen måste fostret få två anlag, ett från vardera föräldern, vilket är 25% risk vid varje graviditet för föräldrapar där båda är bärare. CF är en dödlig sjukdomCystic Fibrosis (CF) is a severe hereditary disorder leading to progressive deterioration of lung function and death. This thesis describes the demography of CF in Sweden, its treatment, with special reference to physiotherapy, and its effects on lung function and peak working capacity (PWC). The study is based on Swedish CF patients and evaluates our current CF treatment package, which differs fr
Popular Abstract in Swedish Syftet med denna avhandling är att studera den vanligaste behandlingskomplikationen vid blödarsjuka, antikroppsbildning, samt att studera sambandet mellan genen som orsakar sjukdom och det protein som denna gen kodar för. Det övergripande syftet är att forskningsresultaten ska kunna användas för att förbättra vården för familjer med blödarsjuka (hemofili). Resultaten vThe general objective of the research underlying this dissertation was to conduct clinical and basic scientific studies to further elucidate the hemophilia and the coagulation process, with the goal of improving the care of families with these disorders. More specific aims were to evaluate epidemiological, genetic, clinical, and biochemical aspects of the development of inhibitors (antibodies) aga
It is shown that the isoscalar strength in the energy region just above the low energy threshold, which is created by exciting particles to the continuum in nuclei far from β-stability lines, can be reduced by the attractive coupling to isoscalar shape oscillations. This is in contrast to the well known fact that in β-stable nuclei low lying isoscalar particle hole strengths are always increased b
Popular Abstract in Swedish Avhandlingen behandlar ekonomisk tillväxt och finanspolitik. Med ekonomisk tillväxt avses tillväxttakten i BNP – det sammanlagda värdet av alla varor och tjänster som produceras för slutlig användning i ett land – och med finanspolitik avses handhavandet av de offentliga finanserna. Efter ett introduktionskapitel följer fem kapitel som är fristående från varandra. De trThis thesis deals with the two subjects economic growth and fiscal policy. The first three chapters after the introduction are theoretical approaches to the determination of long-run growth. In each of these chapters, the ability of fiscal policy to influence long-run growth is examined as well. The next chapter relates the development of GDP in the long run to the financial system. The final chap
Twenty years after Vassar College welcomed the first American female undergraduates in 1865, the experiences of women college students began to be fictionalized in so-called college stories. This thesis shows how higher education is presented in the novels, collections of short stories, and serialized stories for female readers published before the United States was involved in the First World Wa
Popular Abstract in Swedish Från 1865 och framåt öppnades i nordöstra U.S.A ett antal college där unga kvinnor kunde avlägga en icke yrkesinriktad akademisk examen. Efter några decennier använde några som utexaminerats från dessa institutioner sina erfarenheter i populära berättelser om studenter på college. Avhandlingen visar hur denna utbildning presenteras i skönlitterär form. Fokus ligger på Twenty years after Vassar College welcomed the first American female undergraduates in 1865, the experiences of women college students began to be fictionalized in so-called college stories. This thesis shows how higher education is presented in the novels, collections of short stories, and serialized stories for female readers published before the United States was involved in the First World Wa
Inflammation is a physiological response that may go uncontrolled and thereby develop in a chronic way. This seems to happen in many common diseases of autoimmune, degenerative, or allergic character. Rheumatoid arthritis (RA) is by definition a chronic disease with an autoimmune inflammatory attack on diarthrodial cartilaginous joints. The development of new treatment neutralizing cytokines invol
I Sverige har under de senaste åren ungefär 19 000 barn under 15 år årligen misstänkts för att ha begått ett brott. Det finns dock ingen bra samlad statistik då barn under 15 år inte kan lagföras för brottet. När ett barn misstänks för ett brott har polisen en anmälningsplikt till socialtjänsten. Om det begångna brottet har minst ett års fängelse i straffskalan eller om socialtjänsten begär det skDuring the last few years approximately 19 000 children below the age of 15 have been suspected for committing an offence. However there is no comprehensive statistics when children below the age of 15 cannot be charged for the offence. The police must report all children who are suspected for committing a crime to the local social services. If the minimum sentence for the committed crime is one y
The capabilities of ultrasound optical tomography (UOT) is investigated through Monte Carlo simulations on realistic breast tissue phantoms constructed using the OpenVCT platform. This work indicates that UOT is a method capable of distinguishing malignant tumor tissue from benign glandular tissue deep inside the breast, despite the natural variations of adipose and glandular compartments within a
Background: Family is a crucial social institution in end-of-life care. Family caregivers are encouraged to take on more responsibility at different times during the illness, providing personal and medical care. Unpaid work can be overburdening, with women often spending more time in care work than men. Objectives: This study explored multiple views on the family’s role in end-of-life care from a
Acquisition of irregular verb forms in L2 French: does the L1 of the learners explain the difference ? This study explores L1 effects on the production of subject-verb agreement in number (singular vs. plural) in L2 French. L1 influence has rarely been explored in detail in this context, especially compared to other factors such as input frequency of specific verb forms, singular vs plural entitie
The retinoblastoma gene product (pRb) is involved in both cell cycle regulation and cell differentiation. pRb may have dual functions during cell differentiation: partly by promoting a cell cycle brake at G(1) and also by interacting with tissue-specific transcription factors. We recently showed that pRb mediates differentiation of leukemic cell lines involving mechanisms other than the induction
Det är mycket rörelse på AI-fronten nu – både rättsligt, tekniskt och politiskt. Stefan Larsson, jurist och docent i teknik och social förändring vid Lunds universitet, placerar in EU-lagstiftarens AI-förordning i en både global och svensk kontext. Han beskriver processen bakom lagstiftningen, de etiska och principiella grunderna, och hur EU-lagstiftaren hanterar AI-innovationernas explosionsartad
Forests provide a wide range of ecosystem services, and ecosystem models can be applied to assess the contribution of different forest management strategies to climate mitigation and adaptation. Complex model output and trade-offs between environmental, economic, and social sustainability dimensions are difficult to convey. To facilitate stakeholder communication, we developed composite indicators
There is increased awareness of palliative care needs in people with COPD or interstitial lung disease (ILD). This European Respiratory Society (ERS) task force aimed to provide recommendations for initiation and integration of palliative care into the respiratory care of adult people with COPD or ILD. The ERS task force consisted of 20 members, including representatives of people with COPD or ILD
Background: The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in many indications, the toxicities of the current treatment regimens may limit their use. Thus, there is a medical need for new CT
A new focal plane detector system for the Berkeley Gas-filled Separator (BGS) was designed, constructed, and tested offline with various -decay and conversion-electron sources. The SuperHeavy RECoils (SHREC) detector comprises sets of double-sided silicon strip detectors arranged in an open-faced cuboid geometry. Alongside the detector upgrade new digital data acquisition electronics have been com
For patients with gastroenteropancreatic neuroendocrine tumours (GEP-NET), health-related quality of life (HRQoL) is important. Meanwhile, whether tumour volume is associated with HRQoL is unknown. Hence, the aim of this study was to assess if total somatostatin receptor expressing tumour volume is correlated with HRQoL in patients with metastatic GEP-NET. Some 71 patients were included in the stu
