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Adverse life events during pregnancy may impact upon the developing fetus, predisposing prenatally stressed offspring to the development of psychopathology. In the present study, we examined the effects of prenatal restraint stress (PS) on anxiety- and depression-related behavior in both male and female adult Sprague-Dawley rats. In addition, gene expression profiles within the hippocampus and fro
Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygou
Molybdenum complexes of 3,6-di-tert-butylcatechol have been prepared from the reaction between [Mo(CO)6] and 3,6-di-tert-butyl-1,2-benzoquinone. A putative "[MoO(3,6-DBCat)2]" monomer is assumed to form initially by reaction with trace quantities of oxygen. Condensation of the reaction mixture leads to the formation of oligomeric products, including the [{MoO(3,6-DBCat)2}4] chiral square isolated
In multi-view sports broadcasting, extracting high-quality highlights and selecting the optimal camera angle from concurrent video streams is traditionally a labor-intensive process with significant computational overhead. This thesis explores the feasibility of automating the production of multi-view sports highlights using Multimodal Large Language Models (MLLMs). To manage the high computatio
BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and
While the risk for arterial vascular disease has been shown to be influenced by socioeconomic status (SES), there is limited information whether SES also influences the risk for venous thromboembolism (VTE). To evaluate whether there is an association between SES and VTE incidence. In 1990, all 730,050 inhabitants (379,465 women and 350,585 men) above 25 years of age in the County of Skåne in Swed
Greetings from Sune Sunesson, Director It has been a busy couple of months for the Pufendorf IAS (Pufendorfinstitutet). Now it is almost summer and we would like to take the opportunity to wish all of you a very enjoyable break. It is our ambition that the newsletter will become an arena for sharing news and information about current or completed transdisciplinary work - so please email us if you
This thesis analyses the impact of several natural resources on economic growth in the empirically rather poor Sub-Saharan Africa during the time period of 1990-2010. By performing panel regression analyses based on economic and political data from the countries in Sub-Saharan Africa, the conclusion that the production of diamonds promotes economic growth the most could be made. As an example, the
In a number of autoimmune diseases, for example, rheumatoid arthritis and systemic lupus erythematosus, it is known that autoantibodies are present before the clinical onset. Recently we have shown that autoantibodies can be found many years before symptom onset in primary Sjögren's syndrome. This implies that screening for autoantibodies may be used to identify individuals at risk of developing s
The new year in Sweden began with some record-breaking cold temperatures. Temperatures in the village of Kvikkjokk in the northern Swedish part of Lapland dropped to -43.6°C, the lowest recorded since records began in 1887.Yet for the majority of Swedish households, heating is not an issue. Those living in the multi-household apartment blocks that characterise Sweden’s towns and cities enjoy avera
Popular Abstract in Swedish Denna avhandling handlar om modeller för plana solfångare, transparent isolering och verkningsgradsfaktorer. En ekvation för energiutbytet från en glasad plan solfångare härleds genom att modellera verkningsgradsfaktorn, F´, som en summa av en konstant och en temperaturberoende del. Ett alternativt sätt att testa en plan solfångare, baserat på denna modell, föreslås. EThis thesis deals with models of flat plate collectors, transparent insulation and efficiency factors. An equation for the energy output from a glazed flat plate collector is derived by modelling the collector efficiency factor, F´ as the sum of a constant and a temperature dependent part. An alternative way of testing a flat plate collector, based on this model, is suggested. A complete set of a
