Filetype
Existing criteria recommended by ACC/ESC for identifying patients with ST-elevation myocardial infarction (STEMI) from the 12-lead ECG perform with high specificity (SP), but low sensitivity (SE). In our previous study, we found that the SE of acute ischemia detection can be markedly improved without any loss of SP by calculating, from the 12-lead ECG, ST elevation in 3 vessel-specific leads (VSLs
Despite increasing access to antiretroviral treatment (ART) in low-income countries, HIV-related mortality is high, especially in the first months following ART initiation. We aimed to evaluate the impact of TB coinfection on early mortality and to assess gender-specific predictors of mortality in a cohort of Ethiopian adults subjected to intensified casefinding for active TB before starting ART.
The MAX IV facility includes two storage rings operated at 1.5 GeV and 3 GeV. Both rings make use of a 100 MHz RF system and are designed to operate with a uniform multibunch fill pattern aswell as employ passive harmonic cavities to damp instabilities and increase Touschek lifetime. Recently, a discussion on timing modes at the MAX IV storage rings has been initiated by the user community. This i
Background: Sierra Leone is a low income country in West Africa that has a history of conflict. Sierra Leone have signed and ratified the Convention of Rights of Persons with Disabilities.Aim: To evaluate persons with disability that use prosthetic and orthotic assistive devices access to human rights. The addressed areas were; right to health, right to a standard of living adequate for health, ri
The paper analyses some properties that are obtained when using load current measurements to control DC-DC power converters. The analysis is made for the buck, boost, and buck-boost converters with current mode control. The two major properties obtained are low output impedance and an almost invariant control-to-output transfer function for different loads. It is shown that the use of the load cur
The predictive value of distal blood pressure measurements for the level of amputation was studied prospectively in 161 consecutive diabetic patients with foot ulcers. The patients were treated as outpatients except for periods of surgery and when complications requiring hospital care occurred. All patients were treated pre- and postoperatively by the same multidisciplinary foot care team. Either
The optical efficiency of concentrating solar thermal and photovoltaic systems with cylindrical geometries is asymmetrical about the optical axis. Biaxial models, based on projected incidence angles, are often used to estimate the annual performance of asymmetric concentrators. However, the use of projected angles tends to underestimate optical losses in the cover glass. In this work, a biaxial mo
Objective To estimate the cost-effectiveness of a new treatment (natalizumab) for multiple sclerosis (MS) compared with current standard therapy with disease-modifying drugs (DMDs) in Sweden. Methods A Markov model was constructed to illustrate disease progression based on functional disability (the Expanded Disability Status Scale (EDSS)). The effectiveness of natalizumab was based on a 2-year cl
Right ventricular rupture, resulting in serious bleeding, is a life-threatening complication associated with negative-pressure wound therapy (NPWT) in cardiac surgery. The use of a rigid barrier between the heart and the sharp sternal edges has been successfully tested on pigs. In the present article, we demonstrate increased safety in NPWT through the use of the HeartShield device.
During formation of polymorphonuclear neutrophils, proteins are synthesized for storage in granules. Whereas sorting of proteins into distinct subtypes of cytoplasmic granules may reflect the coordinated expression of the proteins contained in them, still the mechanism(s) for the retrieval of proteins from the constitutive secretion is unknown. To investigate the mechanisms of retrieval, nonmyeloi
The purpose of this study was to identify new prognostic biomarkers with clinical impact in malignant peripheral nerve sheath tumor (MPNST), a highly aggressive malignancy for which no consensus therapy exists besides surgery. We have used tissue microarrays (TMAs) to assess in situ expression of 14 cell-cycle-regulating proteins in 64 well-characterized MPNST patients: 36 sporadic and 28 with neu
A global existence result for solutions u(t) of the differential equation x" + f(t, x) = p(t), t >= t(0) >= 1, that can be written as u(t) = P(t) + o(l) for all large t, where P"(t) = p(t), is established by means of the Schauder-Tikhonov theorem. It generalizes the recent work of Lipovan [On the asymptotic behaviour of the solutions to a class of second order nonlinear differential equations, Gla
Polymeric nanoparticles is an established and efficient means to achieve controlled release of drugs. Incorporation of minocycline, an antibiotic with anti-inflammatory and neuroprotective properties, into biodegradable nanoparticles may therefore provide an efficient means to combat foreign body reactions to implanted electrodes in the brain. However, minocycline is commonly associated with poor
A modified local error model is developed for numerical integration of ODEs with invariants. The basic idea is to use a commutativity relationship that holds for implicit state-space form methods. A new implicit state-space form predictor is developed from which error estimates can be obtained by predictor-corrector difference: This technique is demonstrated through the preliminary examples in thi
Follow-up of endovascular aneurysm repair (EVAR) with life-long computed tomography angiography (CTA) surveillance exposes patients with impaired renal function to repeated risks of contrast medium-induced nephropathy (CIN).
To identify from a patient's perspective, difficulties and differences in the comprehension of five global presenteeism measures in patients with inflammatory arthritis and OA across seven countries.
