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BackgroundDespite the high morbidity and severe consequences of epidermolysis bullosa (EB), current treatments remain inadequate, lacking efficacy and the ability to target the microbial and inflammatory components of EB wounds. In this first-in-human open-label, single-arm study—part 3 of a 3-part Phase 1 clinical trial—we examined the safety, tolerability, and systemic exposure of topically appl

Continuity of care is one of the core values of family medicine and both patients and doctors consider it a vital aspect of the care of patients with chronic diseases. In 2009 a national health care reform was implemented in primary care in Sweden. This study compared the longitudinal continuity of care in primary care before and after this reform in 7121 adult diabetes patients living in Malmö. O

Vid kronisk myeloisk leukemi har målstyrd, kontinuerlig behandling med tyrosinkinashämmare lett till dramatiskt förbättrad överlevnad. Efter ett flertal år uppnås djupt molekylärt svar hos ca 50 procent av patienterna; ca 50 procent av dem kan då avbryta behandlingen utan tecken på återfall. Kontinuerlig behandling med tyrosinkinashämmare kan ge långsiktiga biverkningar. Efter patentutgång för imaChronic myeloid leukemia - a model disease for targeted therapy Chronic myeloid leukemia (CML) pioneered as the first human malignancy linked to a specific cytogenetic aberration (the Philadelphia chromosome), which led the way to specific targeted therapies with imatinib (Glivec) and later tyrosine kinase inhibitors (TKI). Continuous TKI administration, blocking the oncogenic fusion protein Bcr-A

Emergency Medicine became a supraspeciality in Sweden in 2008. The Swedish Specialist Examination in Emergency Medicine is a formative examination that seeks to guide local training in Emergency Medicine, provide feedback to physicians during their residency, and establish national standards for various processes in Emergency Medicine. It consists of six partial examinations and 118 cases. Documen

The fact that we apprehend certain phenomena as more convenient than others generate questions about what constitute and decide what we think of as normal and appropriate. The aim of this thesis is to explore the immense conception of power and authority through a narrower approach that focuses on the EU. With this in mind I examine the penetration of the neo-liberal ideology in the Treaty establ

Denna uppsats syftar till att undersöka om möjligheterna till resning i brottmål till förmån för en tilltalad, avgränsat till resningsgrunden nya omständigheter och bevis, är tillräckliga. Resningsbestämmelserna bygger på en avvägning mellan intresset av att en lagakraftvunnen dom förblir orubblig, orubblighetsprincipen, och intresset av materiellt riktiga avgöranden, sanningsprincipen. OrubbligheThe purpose of this thesis is to examine if the possibilities to grant new trial in favour of the defendant in criminal cases are sufficient, limited to new circumstances and evidence as cause for new trial. The new trial provisions are based upon a consideration between the rule of immovability and the rule of truth, that is, the interest of an immovable legally binding judgment opposite the inte

Syftet med denna studie var att med hjälp av suppliker och resolutioner undersöka vilken legitimitet som den danska ockupationsmakten hade hos den skånska allmogen under kriget i Skåne 1676-1679. Viktiga teorier för att besvara denna fråga har varit Jan Gletes teori om att staten producerade beskydd för att detta efterfrågades av undersåtarna. Kopplat till det här är Barrington Moore jr. resoneman