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The thermal environment experienced by birds during early postembryonic development may be an important factor shaping growth and survival. However, few studies have directly manipulated nest temperature (T n) during the nestling phase, and none have measured the consequences of experimental heat stress on nestlings’ body temperature (T b). It is therefore not known to what extent any fitness consThe thermal environment experienced by birds during early postembryonic development may be an important factor shaping growth and survival. However, few studies have directly manipulated nest temperature (T n) during the nestling phase, and none have measured the consequences of experimental heat stress on nestlings’ body temperature (T b). It is therefore not known to what extent any fitness cons

Objectives This study sought to study the second-generation everolimus-eluting stent (EES) as compared with first-generation sirolimus-eluting (SES) and paclitaxel-eluting stents (PES) in diabetes mellitus (DM) patients. Background There are limited data available comparing clinical outcomes in this setting with EES and SES, whereas studies comparing EES with PES are not powered for low-frequency

Advanced therapy medicinal products (ATMPs) are complex biological products that present specific scientific and regulatory challenges during clinical development. This thesis aimed to analyse consolidated Part I considerations raised during assessment of investigational ATMP clinical trial applications (CTAs) under the Clinical Trials Regulation (CTR) to identify recurring scientific and regulato

Abstract - Vol. I In this Volume of the thesis, which consists of two volumes, a risk analysis framework for application in the maritime transport system of packaged dangerous goods (PDG) is presented. In many countries, dangerous goods risks have been ranked high among public concerns. Such concerns are mainly due to the increasing volume of dangerous goods, human safety and health and environme

Overproduction of membrane proteins can be a cumbersome task, particularly if high yields are desirable. NADH:quinone oxidoreductase (complex I) contains several very large membrane-spanning protein subunits that hitherto have been impossible to express individually in any appreciable amounts in Escherichia coli. The polypeptides contain no prosthetic groups and are poorly antigenic, making optimi

Background: End-stage kidney disease overwhelms health services in Central America. We determined prevalences of decreased kidney function in distinct populations in the most affected region of Nicaragua. Study Design: Cross-sectional survey. Setting & Participants: Total populations aged 20-60 years of 5 villages in Northwest Nicaragua: mining/subsistence farming (elevation, 100-300 m above s

Tapasin is a subunit of the transporter associated with antigen processing (TAP). It associates with the major histocompatibility complex (MHC) class I. We show that tapasin interacts with beta- and gamma-subunits of COPI coatomer. COPI retrieves membrane proteins from the Golgi network back to the endoplasmic reticulum (ER). The COPI subunit-associated tapasin also interacts with MHC class I mole

We investigate the potential of different pre-fetching and/or caching strategies for different user behaviour with respect to surfing or browsing in a catch-up-TV network. To this end we identify accounts and channels associated with strong or weak surfing or browsing respectively and study the distributions of hold times for the different types of behaviour. Finally we present results from a requ

The Oxytocin Me! project has proven to be a response to the nowadays increasing focus on high technology. The topic I have chosen is both a health and social matter: stress. In this regard, I have developed a stress relieving product that should challenge people to use their body’s own natural resources. The result is an ergonomic hug cushion that should stimulate the body to produce oxytocin hor

In recent years there has been a large increase in available data from the electric grid in Finland. The availability of both operational as well as financial data enables exploration of forecasting energy prices using deep learning techniques. As a result this thesis implements the Multi-Horizon Quantile Recurrent Neural Network (MQRNN) to forecast the regulating price in the Finnish energy marke

The study aims to investigate whether diversity can affect people's social intelligence. The study has been conducted with an experimental design, where two experimental groups were primed with a text describing a workplace with a high degree of diversity respectively non-diversity. A control-group read a neutral text. The texts were followed by the self-assessment test Tromsö Social Intellige

In this paper youth representation among Swedish local government politicians is examined. Although youth people (18-29 years) constitute 20% of the electorate only about 7 percent of the politicians are young. This means youths are represented at a quota of 37% compared to the other age groups that average at least 100%. The study aims to fins explanations in terms of individual resources and pol

Denna undersökning analyserar vad som påverkar hur väl FN:s genusrelaterade resolutioner implementeras i EU:s civila och militära operationer, där åtta EU-administrerade uppdrag undersöks. Syftet med studien är att undersöka vilka faktorer som ligger till grund för problematiken kring bristande implementering av genusperspektivet, men även varför det varierar mellan de olika operationerna. Detta g

This paper aims to examine whether the Federal Communications Commission’s (FCC) debate during 2017 regarding the bill “Restore internet Freedom” can be understood through a theoretical neo-liberal and social-liberal ideological perspective. The purpose of this paper is to clarify and bring an understanding of what was said in the debate regarding the bill, by trying to interpret what political id

This paper aims to discover viable ways in which the Global South can effectively challenge the primacy of the Global North, in order to create a more equitable global order. This thesis is premised on a dependency approach to international relations which stipulates that the Global South, or Third World, is underdeveloped because of actions by the Global North, or the First World. The legacy left

Ledstjärnan inom svensk miljörätt är att förebygga skador på människor och miljö i så stor utsträckning det är rimligt och möjligt. Utöver dessa preventiva regler finns även reparativa krav som aktualiseras först när en skada på miljön redan skett. Dessa reparativa krav grundar sig i ”principen om att förorenaren ska betala” vilket innebär att den som har orsakat en skada på miljön är ansvarig förThe main purpose of the Swedish Environmental Code is to prevent damage on the environment. In addition to this the Code also contains restorative requirements that apply only when an environmental damage has already occurred. These reparative claims are based on the so called ”Polluter Pays Principle” which states that the one who caused the damage to the environment is liable for the restorative

In 2014 five member states of the European union recieved 72 percent of all asylum applications that reached the union. This uneven distribution happend in spite of the fact that the Common European Asylum System (CEAS) since the adoptation of the Lisbon treaty according to article 80 TFEU is supposed to be governed by the princip of solidarity and fair sharing of responsibility. One explanation t

Sanctions have become a frequently used tool of political interactions around the globe, and the U.S. is he leading countries when it comes to imposing economic sanctions. While the intention of economic sanctions is to put pressure on the target to alter its behaviour, research has shown that economic sanctions can have negative effects even on the sender country. Utilising a difference-in-differ