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There are several different preventive measures that can be used to reduce the number of fire fatalities in residential buildings, but information on how effective different measures are for different groups are, however, lacking. As a result, general measures are often implemented on large portions of the total population, which is not as cost-effective as targeting certain measures for certain g
Scholarship on branding has made important contributions in terms of the value-creating function of branding. However, previous literature has overemphasized the creation of value for organizations at the expense of an understanding of the destructive side of branding for organizations and society. Drawing on the work of Boltanski and Thevénot, we theorize value as different in separate ‘worlds of
Environmental Product Declarations (EPDs) are used to communicate product's environmental performances to relevant stakeholders, whereas Product Category Rules (PCRs) provide guidelines for making EPDs in different product categories. Little is known regarding the cost for developing EPDs and PCRs. We therefore conducted an international survey, and 15 responses from EPD certification operators we
This paper uses an analytical framework of multi-level and multi-phase perspectives to explore low carbon transition pathways for the UK road transport system. The work draws on the impact made by the national (UK) and regional (EU) low carbon policy instruments on the UK road sector. The results show that the transformation pathway, which is at the take-off phase on a large scale, is the only ful
In this study, the processes behind observed new particle formation (NPF) events and subsequent organic-dominated particle growth at the Pallas Atmosphere-Ecosystem Supersite in Northern Finland are explored with the one-dimensional column trajectory model ADCHEM. The modeled sub-micron particle mass is up to ∼75 % composed of SOA formed from highly oxidized multifunctional organic molecules (HOMs
The development of cities is increasingly threatened by a worldwide water crisis. Urban water services (including drinking water, sanitation and drainage) are facing complex and multiple pressures, which are becoming increasingly frequent and severe. These pressures include floods, and the depletion, pollution and degradation of water resources and their associated ecosystems. These diverse pressu
In this paper, we shall be concerned with geometric functionals and excursion probabilities for some nonlinear transforms evaluated on Fourier components of spherical random fields. In particular, we consider both random spherical harmonics and their smoothed averages, which can be viewed as random wavelet coefficients in the continuous case. For such fields, we consider smoothed polynomial transf
The UN Charter describes him or her merely as the “chief administrative officer of the organization,” yet today the Secretary-General is widely recognized as the UN’s chief political representative. How did this transformation and expansion of the office from administrative to political take place? Existing scholarship tends to emphasize the contribution made by Dag Hammarskjöld. This article chal
Aims/hypothesis. Islet cell autoantibodies are a specific marker for Type 1 (insulin-dependent) diabetes mellitus. Standardisation of islet cell antibodies and the uniform reporting in International units is critical to research and the development of assays for islet cell autoantibodies as diagnostics. Methods. The suitability of a candidate serum to serve as the international standard for islet
We describe a novel monoclonal antibody raised towards the N-terminus of the 65 kDa isoform of glutamate decarboxylase (GAD65). This N-GAD65 mAb is highly specific for GAD65 and can be used in a wide range of applications such as Western blot analysis, immunoprecipitation and immunocytochemistry. Full-length cDNAs coding for N-GAD65 mAb heavy and light chains were cloned and characterized by nucle
This paper presents two case studies of Swedish ICT 'gap exploiter' companies to provide a nuanced perspective in the investigation of ICT reuse business models and policies. Gap exploiters are third-party firms that create value through the re-utilization of existing products. While extending product life through the gap exploiter model is promising in the transition to a circular economy, busine
Self-other similarity judgment asymmetry refers to the tendency of people to judge others to be more similar to themselves than they judge themselves to be similar to others. This effect can be explained with both a cognitive model (Tversky, 1977) and a motivational explanation (Codol, 1987). Recent research has provided initial evidence for the core assumption of the motivational explanation and
The international standard ISO 22400 has defined a set of Key Performance Indicators (KPIs) to evaluate the performance of manufacturing operation. However, the defined KPIs seem to be inspired from the discrete production context, and hence do not automatically fit the process industry context. The process industry is defined as the industry in which the raw material undergoes conversion during a
The neuropeptide calcitonin gene-related peptide is well established as a key player in the pathogenesis of migraine. Clinical studies show calcitonin gene-related peptide levels correlate with migraine attacks, and decreases in this neuropeptide can indicate antimigraine therapy effectiveness. Research has revealed a wide distribution of expression sites for calcitonin gene-related peptide in the
This In Memoriam presents the life of Simone Veil, an influential French politician, remembered for a law that made abortion legal in 1974. Simone Veil's contribution to the rights of women is featured as an instance of parrhesia (Foucault, 2011) that was able to establish a new regime of truth about the body, sexuality, and reproductive capacities of French women.
Background: In recent years, our group has developed electro-optical remote sensing methods for the monitoring and classification of aerofauna. These methods include active lidar methods and passive, so-called dark-field methods that measure scattered sunlight. In comparison with satellite- and airborne remote sensing, our methods offer a spatiotemporal resolution several orders of magnitude highe
Tumors are phenotypically heterogeneous and include subpopulations of cancer cells with stemlike properties. The natural product salinomycin, a K+-selective ionophore, was recently found to exert selectivity against such cancer stem cells. This selective effect is thought to be due to inhibition of the Wnt signaling pathway, but the mechanistic basis remains unclear. Here, we develop a functionall
Laminin α2 chain-deficient muscular dystrophy, or LAMA2-CMD, is a very severe disease caused by mutations in the LAMA2 gene. Skeletal muscle is the most affected tissue, with patients presenting symptoms such as hypotonia at birth, joint contractures and progressive muscle wasting. Changes in the central nervous system include white matter abnormalities, delayed motor milestones and compromised ac
Extracting microanatomical information beyond the image resolution of MRI would provide valuable tools for diagnostics and neuroscientific research. A number of mathematical models already suggest microstructural interpretations of diffusion MRI (dMRI) data. Examples of such microstructural features could be cell bodies and neurites, e.g. the axon's diameter or their orientational distribution for
