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BACKGROUND: Neutralizing antibody assessments play a central role in human immunodeficiency virus type-1 (HIV-1) vaccine development but it is unclear which assay, or combination of assays, will provide reliable measures of correlates of protection. To address this, an international collaboration (NeutNet) involving 18 independent participants was organized to compare different assays. METHODS: Ea
Elements of the Ordovician conodont genus Protopanderodus have been investigated in order to provide a model of reconstruction for its oral apparatus. In total, 4202 elements from the five named species representing this genus in the Swedish Middle Ordovician are included in this study; P. rectus, P. parvibasis, P. graeai, P. robustus, and P. calceatus. The well-preserved specimens were studied in
Popular Abstract in Swedish Det finns ett stort behov av molekyler eller reagenser för korrekt och snabb diagnos och/eller behandling av sjukdom. På laboratorier används särskilda verktyg för att ta fram sådana reagenser. Verktygen utgörs ibland av levande organismer, som t ex bakterier och virus, och kallas bioteknologiska verktyg. Ett av dessa verktyg baseras på användandet av en speciell typ avPhage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. Phage display technology is based on the use of recombinant DNA technology, bacteria and a special kind of bacterial virus,
The duration-time concept, vastly successful for interpreting the frequency dependence of resonant radiative and nonradiative x-ray scattering spectra, is tested for fine-scale features that can be obtained with state of the art high-resolution spectroscopy. For that purpose resonant photoelectron (RPE) spectra of the first three outermost singly ionized valence states X 2Σg+, A 2Πu, and B 2Σu+, a
This memo reports on factors that drive and inhibit the digitalization of security systems. The reported factors are as follows: Technology-push factors • Need to lower costs on the end-user side, i.e. replacing labour with technology • Perceived convenience and ease-of-use of digital systems • Digital products can be connected to the current enterprise network; enabling an expanding set of secur
A mathematical framework is introduced for optimization of antenna near-field imaging problems, based on the multipole expansion of the electromagnetic field, the Fisher information to quantify the quality of data and use of modern interior point convex optimization techniques. We consider the general problem of optimizing the measurement sensor allocation for parameter estimation in distributed s
In order to prepare for the potentially negative influence of insertion devices (IDs) on beam lifetime, injection effi- ciency and beam size in the MAX IV 3 GeV storage ring, a strategy for neutralizing the foreseen effects of the IDs has been developed. The strategy involves a local correction of the betatron phase advance by adjusting the strength of the quadrupoles adjacent to the ID as well as
Industrial packaging contains the parts of final products and is used in the handling and transport of them from the component supplier to the manufacturing company. An increased interest and emphasis on industrial packaging is necessary if the associated potential benefits in terms of costs, efficiency and effectiveness of packaging related activities are to be realized (related activities are th
Universal perception and production constraints may constitute phonetic preconditions for historical sound change. It is pointed out that the traditional literature on the Swedish dialects provides a rich source of information in evaluating the diachronic role played by these constraints.
Modelling is a fairly mature technology that is already being adopted by industry. Unfortunately the tools for supporting Model-Driven Engineering are not at the same level of maturity. In particular merge tools that are an important help for collaboration lack a lot to be desired in providing the support that is needed on industrial projects. Current model merge tools and research approaches focu
The extension of businesses to incorporate the provision of function as a service in supplement to standalone products is an ongoing movement in manufacturing industry. In short, this means that the development intent should be guided by the need of ‘performance in use’ that the customer wants, e.g. thrust rather than an engine. By this, the established knowledge base challenges the development te
