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Scatter correction in SPECT is important for improving image quality, boundary detection and the quantification of activity in different regions. This paper presents a comparison of four scatter correction methods, three using more than one energy window and one convolution-subtraction correction method using spatial variant scatter line-spread functions. METHODS: The comparison is based on Monte
Popular Abstract in Swedish Hjärnan är ett komplext system, som är uppbyggd av många olika sorters celler. Alla dessa celler har sitt ursprung i en speciell typ av cell, stamcellen. Neurala stamceller är omogna celler som har förmågan att genom delning både föröka sig själva genom att bilda fler stamceller, och ge upphov till de olika mogna celltyper som finns i hjärnan. Mycket av intresset för deThe molecular specification of neural precursor cells has been suggested to be a progressive process, with a transition from an early requirement for extrinsic signals to intrinsic mechanisms. Thus, the cells in the nervous system acquire distinct fates in response to extrinsic signals, which activate repertoires of transcription factors in a region and cell type specific manner. The studies in th
Silicon microchips with immobilized antibodies were used to develop microfluidic enzyme immunoassays using chemiluminescence detection and horseradish peroxidase (HRP) as the enzyme label. Polyclonal anti-atrazine antibodies were coupled to the silicon microchip surface with an overall dimension of 13.1 x 3.2 mm, comprising 42 porous flow channels of 235-mum depth and 25-mum width. Different immob
Popular Abstract in Swedish Det är idag viktigt att ha tillgång till moderna, snabba och miljövänliga analysmetoder, som är användbara för olika typer av livsmedel. Dagens metoder är arbetskrävande och leder till hantering och konsumtion av stora mängder lösningsmedel. Metoderna är oftast mycket svåra att automatisera på grund av att de innehåller vätske/vätske-extraktionssteg. Ett alternativ tillSample preparation is the most time-consuming step in an analysis. Traditional sample preparation techniques consume large amounts of organic solvents, are time-consuming and are difficult to automate. During the last decade some new extraction techniques have been developed for sample preparation and one of them is supercritical fluid extraction (SFE). This thesis focuses on sample preparation fo
Inquiries into properties of brain structure and function have progressed due to developments in magnetic resonance imaging (MRI). To sustain progress in investigating and quantifying neuroanatomical details in vivo, the reliability and validity of brain measurements are paramount. Quality control (QC) is a set of procedures for mitigating errors and ensuring the validity and reliability of brain
The bond strength between concrete and corroded steel reinforcement bar is one of the main responsible factors that affect the ultimate load-carrying capacity of reinforced concrete (RC) structures. Therefore, the prediction of accurate bond strength has become an important parameter for the safety measurements of RC structures. However, the analytical models are not enough to estimate the bond st
As the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety
Objectives Whether the increased risk of comorbidities, such as cardiovascular disease, in rheumatoid arthritis (RA) can be reverted by particular antirheumatic therapies, or response to these, is unclear but of critical clinical importance. We wanted to investigate whether response to tumour necrosis factor inhibitors (TNFi) translates into a reduced risk for acute coronary syndrome (ACS). Method
Life Cycle Assessment (LCA) studies are valuable tools for identifying high impact processes and redesigning supply chains. However, LCAs have limits, in the sense that they offer insight into relative sustainability and don't question whether a product, or its use, is sustainable in absolute terms. In this intentionally provocative paper, you join Emma, a fictional average American 15-year-old, a
Introduction: Our objective was determining the optimal combinations of cerebrospinal fluid (CSF) biomarkers for predicting disease progression in Alzheimer's disease (AD) and other neurodegenerative diseases. Methods: We included 1,983 participants from three different cohorts with longitudinal cognitive and clinical data, and baseline CSF levels of Aβ42, Aβ40, phosphorylated tau at threonine-181
När socialtjänsten beslutar att omhänderta ett barn och placera det i ett familjehem innebär det ett allvarligt ingrepp i barnets liv. För vissa barn kan beslutet om att samhällsvården ska upphöra dock få lika ingripande konsekvenser. Syftet med uppsatsen är att undersöka hur tvångsomhändertagna barns rätt till familj tillgodoses när en familjehemsplacering ska avslutas. Arbetet utgår från frågestThe decision to take a child into public care and place it in a foster home means a serious interference in a child’s life. However, to some children, the decision to terminate the care could mean just as much an interference. The purpose of the thesis is to examine the right to family for children in compulsory care when a placement in a foster home is to be terminated. The thesis investigates ho
The development of artificial intelligence (AI) for medicine and health care is rapidly evolving. However, the automation, scale and data dependency of AI-driven decision-making and decision-support calls for a reassessment of principal ethical and legal norms of transparency, in the light of these novel methodologies. The quality of AI-driven health care, we argue, is depending on it. In this cha
Solar radiation plays a pivotal role in the energy balance at the Earth's surface, evaporation, snow melting, water requirements of plants, and hydrological control of catchments. In this work, performance of ERA-Interim (a reanalysis dataset) was examined to estimate solar radiation at Ahvaz, BandarAbbas, and Kermanshah weather stations representing the even spatial distribution over Iran using e
Accurate and timely monitoring of streamflow and its variation is crucial for water resources management in watersheds. This study aimed at evaluating the performance of two process-driven conceptual rainfall-runoff models (HBV: Hydrologiska Byråns Vattenbalansavdelning, and NRECA: Non Recorded Catchment Areas) and seven hybrid models based on three artificial intelligence (AI) methods (adaptive n
AIM: To assess the prognostic value of repetitive serum samples of neuron specific enolase (NSE) and S-100B in cardiac arrest patients treated with hypothermia. METHODS: In a three-centre study, comatose patients after cardiac arrest were treated with hypothermia at 33 degrees C for 24h, regardless of cause or the initial rhythm. Serum samples were collected at 2, 24, 48 and 72h after the arrest a
Recent statistics on language diversity among pupils in Swedish secondary school classrooms show that 24% have another L1 than Swedish. Thus, classrooms are multilingual spaces. In the English subject, an 'English Only' ideology dominates, where classrooms are exclusively English-medium, an ideology endorsed by educational policy, agencies like the Swedish Schools Inspectorate, and teacher educato
Every year, the European Respiratory Society (ERS) organises the Lung Science Conference (LSC) in Estoril, Portugal, to discuss basic and translational science. The topic of the LSC 2020 was “Metabolic alterations in lung ageing and disease”. In addition to an outstanding scientific programme, the LSC provides excellent opportunities for career development and inclusion of Early Career Members (EC
Powertrain efficiency is a critical factor in lowering fuel consumption and reducing the emission of greenhouse gases for an internal combustion engine. One method to increase the powertrain efficiency is to recover some of the wasted heat from the engine using a waste heat recovery system e.g. an organic Rankine cycle. Most waste heat recovery systems in use today for combustion engines use the w
This Consensus Opinion summarizes the main aspects of several techniques for performing ovarian antral follicle count (AFC), proposes a standardized report and provides recommendations for future research. AFC should be performed using a transvaginal ultrasound (US) probe with frequency ≥ 7 MHz. For training, we suggest a minimum of 20–40 supervised examinations. The operator should be able to adj
